Mesothelioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-13Clinical Trial Results: A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer [Phase 1, Phase 2]
Phase 1/2 trial results for TC-510 in advanced mesothelin-expressing cancers were terminated with posted results.
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors [Phase 1]
This clinical trial update describes a Phase 1 study of PF-08046049/SGN-BB228 in advanced melanoma and other solid tumors, with the conditio…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma [Phase 2]
A Phase 2 trial of INQOVI (decitabine/cedazuridine) in patients with BAP1 tumor predisposition syndrome and subclinical, early-stage mesothe…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: 177Lu-DOTA-TATE and Olaparib in Somatostatin Receptor Positive Tumours [Phase 1]
Phase 1 trial update evaluating the combination of 177Lu-DOTA-TATE with Olaparib in somatostatin receptor-positive tumors has completed. The…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A phase 1/2 study of TAK-500 with or without pembrolizumab in adults with select locally advanced or metastatic solid tumors; the trial was …
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion [Phase 1]
Bristol-Myers Squibb is conducting a Phase 1 trial of MRTX1719 in MTAP-deleted solid tumors, including mesothelioma, non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: A Study to Assess Long-term Safety of Tazemetostat in Adult Participants of All Ages With Any Disease Treated With Tazemetostat in a Previous Clinical Study [Phase 1, Phase 2]
This document reports the completion of a long-term safety study of tazemetostat in adults who previously received the drug in earlier trial…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) [Phase 2]
Pembrolizumab is being studied in a Phase 2 trial (MK-3475-158/KEYNOTE-158) for advanced solid tumors; the study is currently active but not…
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer [Phase 1, Phase 2]
A Phase 1/2 study of TC-510 from TCR2 Therapeutics in mesothelin-expressing cancers is active but not recruiting, spanning multiple indicati…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers [Phase 2]
Phase 2 study evaluating adoptive transfer of tumor-infiltrating lymphocytes (TIL) for advanced solid cancers, with multiple site-specific i…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors [Phase 1, Phase 2]
A pharmacokinetic study evaluating the combination of lurbinectedin and irinotecan in selected solid tumors has completed (Phase 1/Phase 2).
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CLINICAL_TRIALS trial_result · 2025-04-23Clinical Trial Update: Study of TBio-6517 Given Alone or in Combination With Pembrolizumab in Solid Tumors [Phase 1]
Phase 1 study of TBio-6517 alone or in combination with pembrolizumab in solid tumors was terminated.
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: CheckpOiNt Blockade For Inhibition of Relapsed Mesothelioma [Phase 3]
A Phase 3 trial evaluating checkpoint blockade therapy for relapsed mesothelioma has completed.
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: A Double Blind, Placebo Controlled, Randomized Phase II Study Evaluating Gemcitabine With or Without Ramucirumab , for II Line Treatment MPM [Phase 2]
A Phase II randomized trial evaluating gemcitabine with or without ramucirumab for second-line mesothelioma has completed.
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Dose Individualization of Pemetrexed - IMPROVE-I [Phase 4]
This report provides an update on the Phase 4 IMPROVE-I trial evaluating dose individualization of pemetrexed in non-small cell lung cancer …
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: Phase 1 Dose Escalation and Expansion to Evaluate AROG4-01 in Patients With Advanced Solid Tumors [Phase 1]
This Phase 1 update describes the dose-escalation and expansion study of AROG4-01 in patients with advanced solid tumors, including mesothel…
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: Study of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Types [Phase 1]
A Phase 1 study evaluating MT-8421 as monotherapy and in combination with nivolumab in selected advanced solid tumors has been terminated. T…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels [Phase 1]
Phase 1 trial assessing the pharmacokinetic interactions of itraconazole and rifampin with tazemetostat; results published for patients with…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: PF-06952229 Treatment in Adult Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study of PF-06952229 in adults with advanced solid tumors was terminated. Results were posted on 2024-06-26.
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CLINICAL_TRIALS trial_result · 2024-05-23Clinical Trial Update: Pevonedistat Alone and in Combination With Chemotherapy in Patients With Mesothelioma [Phase 1, Phase 2]
Phase 1/2 trial evaluating pevonedistat alone and with chemotherapy in mesothelioma has been terminated, with results posted in May 2024.
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Two-Part, Open-Label, Multi-Center, Phase 1/2 Study of BIW-8962 as Monotherapy in Subjects With Lung Cancer [Phase 1, Phase 2]
A two-part Phase 1/2 trial of BIW-8962 as monotherapy in lung cancer has been terminated; the study evaluated Non-Small Cell Lung Cancer, Sm…
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CLINICAL_TRIALS trial_result · 2024-02-29Clinical Trial Update: Nivolumab and Ipilimumab +/- UV1 Vaccination as Second Line Treatment in Patients With Malignant Mesothelioma [Phase 2]
Phase 2 trial update evaluating nivolumab and ipilimumab with or without UV1 vaccination as second-line therapy for malignant mesothelioma.
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: DENdritic Cell Immunotherapy for Mesothelioma [Phase 2, Phase 3]
A Phase 2/3 clinical trial update for DENdritic Cell immunotherapy in mesothelioma has completed.
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CLINICAL_TRIALS trial_result · 2024-01-26Clinical Trial Update: Study of RSO-021 in Patients With Malignant Pleural Effusion Due to Advanced/Metastatic Solid Tumors Including Mesothelioma [Phase 1, Phase 2]
A clinical trial update for RSO-021 in malignant pleural effusion due to advanced/metastatic solid tumors including mesothelioma across Phas…
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001) [Phase 2]
Phase 2 trial evaluating niraparib in BAP1- and DDR-deficient neoplasms including mesothelioma and uveal melanoma has completed with results…