Melasma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Comparison of Efficacy of Topical Westerhoff Formula Cream Vs Topical 4% Hydroquinone for the Treatment of Melasma [Phase 4]
Phase 4 clinical trial comparing the efficacy of Westerhoff Formula Cream versus 4% hydroquinone topical for facial melasma has completed.
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Comparison of a New Masterful Preparation to Kligman's Trio in the Treatment of Melasma [Phase 2]
Phase 2 study comparing a new Masterful Preparation to Kligman's Trio for treating melasma has completed.
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Study of the Influence of Blue Light Emitted by Computer / Television Screens on Melasma MELABLUE Study [NA]
This document provides an update on a completed clinical trial investigating whether blue light from computer and television screens influen…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Comparative Evaluation of Topical 30% Metformin and Kligman's Regimen in Women With Melasma [NA]
Clinical trial evaluating topical 30% metformin versus Kligman's regimen for facial melasma in women; recruitment status is not yet recruiti…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Efficacy of Radiofrequency Micro Needling for the Treatment of Melasma in Skin of Color. [NA]
A completed clinical trial evaluating the efficacy of radiofrequency microneedling for treating melasma in people with skin of color.
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Melasma [NA]
A completed clinical trial evaluating umbilical cord mesenchymal stem cell-derived exosomes as a treatment for melasma, sponsored by Fujian …
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Comparison of Efficacy of Metformin Gel 30% vs Triple Combination Cream (Hydroquinone 4%, Flucinolone Acetonide 0.01%, Tretinoin 0.025%) in Treatment of Melasma in Tertiary Care Hospital Karachi [NA]
A completed clinical trial comparing metformin gel 30% to a triple-combination cream for the treatment of melasma at a tertiary care center …
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Azelaic Acid 20% vs Hydroquinone 4% in Epidermal Melasma [NA]
A completed clinical trial comparing azelaic acid 20% with hydroquinone 4% for epidermal melasma (facial melasma). The update notes completi…
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: Comparison of Intradermal Microinjections of Tanexamic Acid and Oral Tranexamic Acid in the Management of Melasma. [EARLY_Phase 1]
A Phase 1 clinical trial comparing intradermal microinjections of tranexamic acid versus oral tranexamic acid for melasma has been completed…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Efficacy and Safety of 30% Salicylic Acid and 10% Nicotinamide Combined Therapy in Melasma [NA]
A completed clinical trial assessed the efficacy and safety of a combined topical therapy consisting of 30% salicylic acid and 10% nicotinam…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Annurca Apple Peel Oleolite for the Treatment of Skin Hyperpigmentation [NA]
A completed clinical trial evaluated Annurca Apple Peel Oleolite for treating skin hyperpigmentation, including melasma and related photodam…
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: Effectiveness of Oral Melatonin vs Oral Tranexamic Acid in the Treatment and Recurrence of Melasma [Phase 4]
Phase 4 clinical trial comparing oral melatonin with oral tranexamic acid for melasma treatment and recurrence. The study is currently activ…
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CLINICAL_TRIALS trial_result · 2025-05-05Clinical Trial Update: Efficacy of Eflornithine Hydrochloride Cream in the Treatment of Melasma: A Randomized, Double-blinded, Split-face Controlled Study [Phase 2]
A Phase 2 randomized, double-blind, split-face trial evaluated the efficacy of eflornithine hydrochloride cream for treating melasma; the st…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: EFFICACY and TOLERABILITY of TESTED FORMULA VS. HYDROQUINONE 4% in the TREATMENT of FACIAL MELASMA [NA]
A completed clinical trial comparing a tested topical formula with hydroquinone 4% for facial melasma evaluated for efficacy and tolerabilit…
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Treatment of Melasma With Yellow Light Compared to Tranexamic Acid [NA]
A clinical trial comparing yellow light therapy to tranexamic acid for melasma was terminated.
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CLINICAL_TRIALS trial_result · 2024-07-26Clinical Trial Update: Fractional Erbium YAG Laser vs Intradermal and Systemic Tranexamic Acid [NA]
This entry notes an ongoing clinical trial comparing fractional Erbium YAG laser treatment with intradermal and systemic tranexamic acid for…
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CLINICAL_TRIALS trial_result · 2023-12-20Clinical Trial Update: Lutronic PicoPlus Exploratory Clinical Trial [NA]
Exploratory clinical trial update for Lutronic PicoPlus (tattoo, pigmentation, melasma) has terminated with results posted.
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: The Effectiveness of 3% Topical Tranexamic Acid Compared to 4% Topical Hydroquinone as Therapy of Melasma [Phase 3]
Phase 3 trial comparing 3% topical tranexamic acid to 4% topical hydroquinone for the treatment of melasma; current status unknown.
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CLINICAL_TRIALS trial_result · 2023-08-28Clinical Trial Update: Comparison Of Efficacy Of Combination Of TAM Formula Vs Kligman Formula For Melasma. [Phase 2]
Phase 2 trial comparing TAM Formula versus Kligman Formula for melasma is in an unknown status.
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CLINICAL_TRIALS trial_result · 2023-08-07Clinical Trial Update: Cysteamine Compared to Hydroquinone in Melasma [Phase 3]
A Phase 3 trial comparing cysteamine to hydroquinone in the treatment of melasma has completed.
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: Tranexamic Acid With Microneedling in Melasma [Phase 2]
Phase 2 clinical trial investigating tranexamic acid with microneedling for melasma.
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CLINICAL_TRIALS trial_result · 2023-05-23Clinical Trial Update: Comparison of 30% Metformin and 2% Nicotinamide Lotion With Kligman Formula in the Treatment of Melasma [Phase 2]
Phase 2 clinical trial comparing a 30% metformin and 2% nicotinamide lotion with Kligman formula for melasma has completed.
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CLINICAL_TRIALS trial_result · 2022-11-03Clinical Trial Update: Efficiency And Safety Of Association Arbutin, Triamcinolone And Tretinoin In Treatment Of Melasma [Phase 2, Phase 3]
Clinical trial update on the combination of arbutin, triamcinolone, and tretinoin for melasma shows Phase 2/3 status with suspension.
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CLINICAL_TRIALS trial_result · 2022-07-29Clinical Trial Update: Assessment of Atrophogenic Potential of Triple Combination Cream for Treatment of Melasma [Phase 4]
Phase 4 trial assessing the atrophogenic potential of a triple combination cream for melasma has been completed.
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CLINICAL_TRIALS trial_result · 2022-07-29Clinical Trial Update: Efficacy and Safety of Therapy With Tri-Luma® Cream in Sequence With Glycolic Acid Peels for Melasma [Phase 4]
Phase 4 trial assessing efficacy and safety of Tri-Luma Cream used in sequence with glycolic acid peels for melasma.