Melasma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Clinical Efficacy and Mechanisms of a Topical Azone-Tranexamic Acid-Aloe Polysaccharide Gel in the Treatment of Melasma [NA]
A clinical trial update describes a topical gel combining tranexamic acid, Azone (laurocapram), and aloe polysaccharide for treating melasma…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Comparison Between Efficacy of Topical Tranexamic Acid Vs Topical Ethyl Ascorbic Acid In Treatment Of Melasma [Phase 4]
A Phase 4 trial comparing topical tranexamic acid to topical ethyl ascorbic acid for melasma is not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Comparative Evaluation of Topical Metformin and Topical Tranexamic Acid in Melasma [NA]
A planned comparative clinical trial evaluating topical metformin versus topical tranexamic acid for melasma. The study is not yet recruitin…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Evaluation of the Efficacy of Oral Tranexamic Acid and Glutathione-assisted Microneedling in Treatment of Melasma [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating the efficacy of oral tranexamic acid and glutathione-assisted microneedling for melasma; the study is no…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Evaluation of Efficacy and Tolerabilty of MelaB3 Serum in Combination of 35% Glycolic Acid Peeling Compared to 35% Glycolic Acid Peeling Alone in Various Hyperpigmentation Conditions [NA]
The trial evaluates the efficacy and tolerability of MelaB3 Serum when combined with 35% glycolic acid peeling versus glycolic acid peeling …
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Expert Consensus on the Clinical Management of Melasma: A Delphi Method Study
Delphi-method study to establish expert consensus on the clinical management of melasma (facial melasma). The study aims to inform clinical …
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Treatment and Prevention of Melasma Relapses by Using 1064nm 650 Microsecond Laser [NA]
Clinical trial update on using a 1064 nm 650 microsecond laser to treat and prevent relapses of melasma; the study is sponsored by Centre Ho…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Ultrasound-Enhanced Delivery of Compound TXA Solution in Melasma [NA]
A clinical trial update notes that ultrasound-enhanced delivery of a tranexamic acid solution (Compound TXA) is being studied for facial mel…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Oral Melatonin Versus Oral Tranexamic Acid in the Management of Melasma [Phase 2]
The document describes a Phase 2 clinical trial comparing oral melatonin with oral tranexamic acid for the management of facial melasma, cur…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Secretome TGF Beta 3 [NA]
A clinical trial is planned to evaluate Secretome TGF Beta 3 for melasma, with status NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: COMPARISON OF A COSMETIC SERUM AND 4% HYDROQUINONE FOR TREATING MELASMA OVER 84 DAYS [NA]
This clinical trial compares a cosmetic serum to 4% hydroquinone for treating facial melasma over 84 days and is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Efficacy and Safety of a Combined Serum Containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES [NA]
Clinical trial update for a topical serum containing Melasyl, 10% Niacinamide, Hyaluronic Acid, and HEPES for melasma and post-inflammatory …
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Comparative Efficacy of Resveratrol 1 % Gel and Trichloroacetic Acid 20% in Treatment of Melasma: A Split-face Study [NA]
This entry describes a split-face clinical trial comparing Resveratrol 1% Gel with Trichloroacetic Acid 20% for treating Melasma, sponsored …
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Stem Cell Derived Exosomes in the Treatment of Melasma and Its Percutaneous Penetration [NA]
This clinical trial is recruiting to evaluate the use of stem cell-derived exosomes for treating melasma and to study their percutaneous ski…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Comparative Effects Of Trichloroacetic Chemical Peel And Fractional Laser [NA]
Clinical trial comparing trichloroacetic chemical peel with fractional laser for treating melasma and acne scars; enrollment by invitation.
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Topical Metformin Versus Topical Ketotifen in Melasma Treatment [Phase 2]
A Phase 2 clinical trial comparing topical metformin versus topical ketotifen for Melasma with recruitment not yet started.
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Oral Metformin for Treating Melasma in Latin American Women [Phase 1, Phase 2]
A clinical trial update describes a Phase 1/2 study evaluating oral metformin for treating melasma in Latin American women, currently recrui…
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CLINICAL_TRIALS research · 2025-01-31Clinical Trial Update: A Pilot Study Testing Salicylic Acid Peels Versus Glycolic Acid Peels for the Treatment of Melasma [NA]
A pilot study comparing salicylic acid peels versus glycolic acid peels for the treatment of melasma; the trial is active but not recruiting…
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CLINICAL_TRIALS research · 2025-01-17Clinical Trial Update: Comparison of Effectiveness and Safety of Triple Combination Cream of Fucinolone Acetonide 0.01%, Hydroquinone 4%, Tretinoin 0.05% with Mometasone Furoate 0.1%, Hydroquinone 4%, Tretinoin 0.05% in the Treatment of Melasma [NA]
This trial compares the effectiveness and safety of two triple-combination topical regimens for melasma: fluocinolone acetonide 0.01%/hydroq…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Clinical Evaluation and Study of the Efficacy of a Centella Asiatica-Infused Facial Mask on Discosmetic Dermatosis [NA]
The trial evaluates a Centella asiatica-infused facial mask for rosacea, acne, and melasma, with status not yet recruiting.
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: Randomized Study Using SM-030 Gel for Adults With Melasma [Phase 2]
A Phase 2 randomized trial evaluating SM-030 Gel for adults with melasma is currently recruiting, sponsored by DermBiont, Inc.
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis [NA]
A clinical trial is recruiting to assess image-based computer gradings for analyzing acne, rosacea, melasma, and seborrheic dermatitis, spon…
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: Development of Products Based on Secretom From Stem Cell Conditioned Medium for Melasma Therapy [NA]
Clinical trial evaluating products based on secretome from stem cell conditioned medium for melasma is currently recruiting.
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CLINICAL_TRIALS research · 2024-07-23Clinical Trial Update: Anti-pigmenting Effect of a Routine of Facial Products in Subjects With Melasma [NA]
This clinical trial update describes a study evaluating the anti-pigmenting effect of a facial product regimen in people with melasma. The t…
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CLINICAL_TRIALS research · 2024-07-09Clinical Trial Update: A Cryotherapy With Tranexamic Acid Versus Normal Saline in the Treatment of Melasma [NA]
A clinical trial comparing cryotherapy with tranexamic acid to normal saline for the treatment of melasma, currently not yet recruiting.