Records containing: MELAS Syndrome
This is the wording recorded or indexed by the source. An agency index term is not necessarily an authorised indication. Co-listed drug names are not linked to this term as a treatment relationship.
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CLINICAL_TRIALS study record update · 2026-02-09Investigational Study of Glycerol Tributyrate in MELAS and LHON-Plus
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CLINICAL_TRIALS study record update · 2025-09-09A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral TTI-0102 for Treatment of Patients With Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)
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CLINICAL_TRIALS study record update · 2025-06-05Global Mitochondrial Registry to Define Natural History and Outcome Measures to Achieve Definite Trial Readiness for Mitochondrial Disorders
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CLINICAL_TRIALS study record update · 2024-06-26Phase-1, Dose Finding and Safety Study on L- Citrulline Treatment of Nitric Oxide Deficiency in MELAS
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CLINICAL_TRIALS study record update · 2023-09-28Clinical Long Term Evaluation of Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome in Order to Prevent Neurological Damage.
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CLINICAL_TRIALS study record update · 2023-08-28Clinical Trial of Ketogenic Diet in the Treatment of Mitochondrial Encephalomyopathy With Lactic Acidosis and Stroke-like Episodes(MELAS)
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CLINICAL_TRIALS study record update · 2022-08-31A Phase IIb Double-blind, Randomised, Placebo-controlled, Multi-centre, Confirmative Three-way Cross-over Study on Cognitive Function With Two Doses of KH176 in Subjects With a Genetically Confirmed Mitochondrial DNA tRNALeu(UUR) m.3243A>G Mutation.
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CLINICAL_TRIALS study record update · 2022-02-24Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome in Order to Prevent Neurological Damage.
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CLINICAL_TRIALS study record update · 2021-10-20A Phase Ia/Ib, Multiple-site Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of KL1333 After a Single and Multiple Ascending Oral Doses in Healthy Subjects and Patients With Primary Mitochondrial Disease
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CLINICAL_TRIALS study record update · 2018-04-27A Dose Block-randomized, Double-blind, Placebo-controlled, Single-dose, Dose-escalation, Phase I Clinical Study
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CLINICAL_TRIALS study record update · 2017-04-21Metabolic and Immune Responses to TIV in Patients With Mitochondrial Disease
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CLINICAL_TRIALS study record update · 2016-08-10A Phase IIa Double-Blind, Randomized, Placebo-Controlled, Dose-Finding Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis and Stroke-like Episodes
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CLINICAL_TRIALS study record update · 2016-04-05Arginine Flux and Nitric Oxide Production in Patients With MELAS Syndrome and the Effect of Arginine and Citrulline Supplementation
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CLINICAL_TRIALS study record update · 2014-04-15Clinical Characteristics and Prognostic Factors of Mitochondrial nt3243 A>G Mutation in Taiwan
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CLINICAL_TRIALS study record update · 2013-12-17Pilot Study to Investigate the Efficacy of L-arginine Therapy on Endothelium-dependent Vasodilation & Mitochondrial Metabolism in MELAS Syndrome.
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CLINICAL_TRIALS study record update · 2012-02-06Ketones & Mitochondrial Heteroplasmy
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CLINICAL_TRIALS study record update · 2008-07-10ClinicalTrials.gov study NCT00004353