Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: A Study Evaluating Efficacy of ABT-888 in Combination With Temozolomide in Metastatic Melanoma [Phase 2]
Phase 2 clinical trial evaluating veliparib in combination with temozolomide in metastatic melanoma has completed, with results posted in 20…
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Adjuvant Therapy of Pegylated Interferon- 2b Plus Melanoma Peptide Vaccine [Phase 1]
A Phase 1 trial evaluated adjuvant therapy with pegylated interferon-2b in combination with a melanoma peptide vaccine for melanoma; the stu…
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CLINICAL_TRIALS trial_result · 2017-03-01Clinical Trial Update: Ipilimumab and Dabrafenib in the 1st Line Tx of Unresectable Stage III/IV Melanoma [Phase 1]
This document reports on a Phase 1 trial evaluating the combination of ipilimumab and dabrafenib as first-line therapy for unresectable stag…
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FDA approval · 2017-02-27FDA Approved: TEMOZOLOMIDE — Original Application (Accord Healthcare Inc.)
FDA approved an original application for temozolomide by Accord Healthcare Inc., authorizing a generic version of the cancer drug temozolomi…
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: Vaccine Therapy in Treating HLA-A2 Positive Patients With Melanoma [Phase 2]
A Phase 2 trial evaluating a vaccine therapy for HLA-A2 positive melanoma patients has completed enrollment and posted results.
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: Interleukin-2 With Sorafenib (BAY 43-9006) for Unresectable or Metastatic Clear Cell Renal Carcinoma (RCC) and Metastatic Melanoma [Phase 1]
Phase 1 trial evaluating the combination of Interleukin-2 with sorafenib for unresectable or metastatic clear cell renal cell carcinoma and …
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CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: Laboratory-Treated T Cells and Aldesleukin After Cyclophosphamide in Treating Patients With Stage IV Melanoma [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluated autologous laboratory-treated T cells and Aldesleukin after Cyclophosphamide in patients with Stage IV…
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CLINICAL_TRIALS trial_result · 2017-02-14Clinical Trial Update: Single-arm Trial to Evaluate the Biodistribution and Shedding of Talimogene Laherparepvec [Phase 2]
Phase 2 single-arm trial assessing biodistribution and shedding of talimogene laherparepvec in melanoma patients; study completed with resul…
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CLINICAL_TRIALS trial_result · 2017-02-03Clinical Trial Update: NIR-Guided Sentinel Lymph Node Mapping in Melanoma [Phase 1]
This update reports completion of a Phase 1 trial evaluating near-infrared guided sentinel lymph node mapping in patients with melanoma.
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CLINICAL_TRIALS research · 2017-02-02Clinical Trial Update: Fluorescence Surgery for Sentinel Node Identification in Melanoma [NA]
An update on a clinical trial evaluating fluorescence-guided sentinel lymph node identification in melanoma. The sponsor is Barretos Cancer …
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Cryoablation or External-Beam Radiation Therapy in Treating Patients With Painful Bone Metastases [Phase 3]
A Phase 3 trial comparing cryoablation versus external-beam radiation therapy for painful bone metastases was terminated; results posted in …
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CLINICAL_TRIALS withdrawal · 2017-02-01Clinical Trial Update: Impact of Obstructive SAS on Metastatic Potential of Cutaneous Melanoma [EARLY_Phase 1]
A phase 1 trial evaluating the impact of obstructive sleep apnea on metastatic potential in cutaneous melanoma has been withdrawn. The study…
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CLINICAL_TRIALS withdrawal · 2017-02-01Clinical Trial Update: A Phase II Trial of Sunitinib and Nivolumab for KIT-mutated Advanced Melanoma [Phase 2]
This document reports the withdrawal of a Phase II trial evaluating the combination of sunitinib and nivolumab for KIT-mutated advanced mela…
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CLINICAL_TRIALS research · 2017-01-26Clinical Trial Update: 18F-Labeled Picolinamide PET Imaging of Melanoma Diagnosis [NA]
This document provides an update on a clinical trial evaluating an 18F-labeled picolinamide PET imaging agent for diagnosing melanoma.
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CLINICAL_TRIALS trial_result · 2017-01-10Clinical Trial Update: Trial of SBRT With Concurrent Ipilimumab in Metastatic Melanoma [Phase 1]
A Phase 1 trial evaluated stereotactic body radiotherapy (SBRT) given with ipilimumab in patients with metastatic melanoma and has completed…
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CLINICAL_TRIALS trial_result · 2017-01-09Clinical Trial Update: A Phase 1 Study of Mixed Bacteria Vaccine (MBV) in Patients With Tumors Expressing NY-ESO-1 Antigen [Phase 1]
Phase 1 study of a mixed bacteria vaccine (MBV) targeting NY-ESO-1 tissue expression in various tumors; completed with posted results.
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CLINICAL_TRIALS trial_result · 2017-01-09Clinical Trial Update: LGX818 in Combination With Agents (MEK162; BKM120; LEE011; BGJ398; INC280) in Advanced BRAF Melanoma [Phase 2]
This Phase 2 trial of LGX818 in combination with multiple targeted agents in advanced BRAF-mutant melanoma was terminated, and results were …
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CLINICAL_TRIALS trial_result · 2016-12-29Clinical Trial Update: A Two-arm, Single Center Phase 1b Trial of Bavituximab Plus Ipilimumab in Advanced Melanoma Patients [Phase 1]
Update on a two-arm, single-center Phase 1b trial evaluating Bavituximab plus Ipilimumab in advanced melanoma, which has been terminated.
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CLINICAL_TRIALS trial_result · 2016-12-23Clinical Trial Update: Pilot Trial to Evaluate the Effect of Vitamin D on Melanocyte Biomarkers [NA]
A completed pilot clinical trial sponsored by Stanford evaluated the effect of vitamin D on melanocyte biomarkers in melanoma/skin condition…
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CLINICAL_TRIALS trial_result · 2016-12-22Clinical Trial Update: IL15 Dendritic Cell Vaccine for Patients With Resected Stage III (A, B or C) or Stage IV Melanoma [Phase 1, Phase 2]
Clinical trial update noting completion of Phase 1 and Phase 2 studies of an IL-15 dendritic cell vaccine in patients with resected stage II…
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: Evaluating the Safety and the Biological Effects of Intratumoral Interferon Gamma and a Peptide-Based Vaccine in Patients With Melanoma [Phase 1]
Phase 1 clinical trial evaluating the safety and biological effects of intratumoral interferon gamma and a peptide-based vaccine in patients…
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: Combination Therapy of Topical Imiquimod Plus Multipeptide Vaccination for Cutaneous Metastases of Melanoma [Phase 1]
Phase 1 trial evaluating the combination of topical imiquimod and a multipeptide vaccine for cutaneous metastases of melanoma has completed.
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CLINICAL_TRIALS research · 2016-12-13Clinical Trial Update: A-dmDT390-bisFv(UCHT1) Fusion Protein With Ionizing Radiation and Pembrolizumab for the Treatment of Stage IV Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial update investigating A-dmDT390-bisFv(UCHT1) fusion protein with ionizing radiation and pembrolizumab for stage IV…
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CLINICAL_TRIALS trial_result · 2016-12-12Clinical Trial Update: An Open-Label Phase II Study of the Combination of GSK2118436 and GSK1120212 in Patients With Metastatic Melanoma Which is Refractory or Resistant to BRAF Inhibitor [Phase 2]
Open-label Phase II trial evaluating the combination of dabrafenib (GSK2118436) and trametinib (GSK1120212) in metastatic melanoma refractor…
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: Nilotinib in TKI Resistant or Intolerant Patients With Metastatic Mucosal, Acral, or Chronically Sun Damaged Melanoma [Phase 2]
Phase 2 trial evaluating nilotinib in patients with metastatic mucosal, acral, or chronically sun-damaged melanoma who are resistant or into…