Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: Ensuring Communication in Hospice by Oncology Study (ECHO) [NA]
The ECHO hospice communication trial, sponsored by Massachusetts General Hospital, has completed and involved patients with ovarian, cervica…
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FDA approval · 2017-04-17FDA Approved: ZELBORAF — Supplemental Application (Genentech, Inc.)
FDA approved a supplemental application for Zelboraf (vemurafenib) submitted by Genentech, Inc. The action updates the drug’s labeling based…
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: Toll-like Receptor (TLR) Ligand Matured Dendritic Cell Vaccination in Melanoma Patients [Phase 1, Phase 2]
This document reports a completed Phase 1/2 clinical trial evaluating a Toll-like receptor ligand–matured dendritic cell vaccine in patients…
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: Single-step Antigen Loading and TLR Activation of Dendritic Cells in Melanoma Patients [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating single-step antigen loading and Toll-like receptor activation of dendritic cells in melanoma patients …
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: The Oncopanel Pilot (TOP) Study
The Oncopanel Pilot (TOP) Study status is listed as completed in this ClinicalTrials.gov update. The update enumerates several cancer indica…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: FDG-PET in Advanced Melanoma [NA]
The trial evaluating FDG-PET imaging in advanced melanoma (NCT02236546) was terminated, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: STA-9090(Ganetespib) in Patients With Unresectable Stage III or Stage IV Melanoma [Phase 2]
This clinical trial update reports a Phase 2 study of ganetespib (STA-9090) in unresectable Stage III or Stage IV melanoma. The study was te…
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: A Phase II Study of Pegylated Interferon Alfa-2b for the Adjuvant Treatment of Melanoma Subjects in Russia (MK-4031-400) [Phase 2]
A Phase II study evaluating pegylated interferon alfa-2b as adjuvant treatment for melanoma in Russia has completed and posted results.
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: A Study of Varlilumab (Anti-CD27) and Ipilimumab and CDX-1401 in Patients With Unresectable Stage III or IV Melanoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating the combination of varlilumab (anti-CD27), ipilimumab, and CDX-1401 in patients with unresectable stage III or …
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CLINICAL_TRIALS trial_result · 2017-04-06Clinical Trial Update: Leflunomide+Vemurafenib in V600 Mutant Met. Melanoma [Phase 1]
A Phase 1 trial evaluating the combination of leflunomide and vemurafenib in patients with V600-mutant metastatic melanoma has been terminat…
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CLINICAL_TRIALS trial_result · 2017-04-05Clinical Trial Update: Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors [NA]
The clinical trial update notes completion of a cognitive-behavioral intervention designed to help cancer survivors manage worry, uncertaint…
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CLINICAL_TRIALS trial_result · 2017-04-05Clinical Trial Update: Evaluation of Intraoperative Usage of Sentinella in Detecting Sentinel Lymph Nodes [NA]
This document reports completed clinical trial evaluating the intraoperative use of Sentinella to detect sentinel lymph nodes.
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Set-back Suture Versus Traditional Vertical Mattress Suture [NA]
A completed clinical trial comparing set-back suture to traditional vertical mattress suture for surgical closure in skin cancer patients. T…
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: A Study of Safety and Clinical Activity of Immunotherapy Plus Chemotherapy in Metastatic Melanoma Patients [Phase 2]
Phase 2 study evaluating safety and clinical activity of an immunotherapy plus chemotherapy combination in metastatic melanoma; the trial wa…
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Rh-endostatin in Combination With Dacarbazine and Cisplatin as the First Line Therapy for Metastatic Melanoma [Phase 2]
A Phase 2 trial investigates rh-endostatin in combination with dacarbazine and cisplatin as first-line therapy for metastatic melanoma. The …
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CLINICAL_TRIALS trial_result · 2017-03-28Clinical Trial Update: Panobinostat (LBH589) in Patients With Metastatic Melanoma [Phase 1]
Phase 1 study of panobinostat (LBH589) in patients with metastatic melanoma has been completed.
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CLINICAL_TRIALS trial_result · 2017-03-24Clinical Trial Update: Phase 3 Trial in Subjects With Metastatic Melanoma Comparing 3 mg/kg Ipilimumab Versus 10 mg/kg Ipilimumab [Phase 3]
Phase 3 trial comparing 3 mg/kg versus 10 mg/kg ipilimumab in metastatic melanoma has been completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-03-22Clinical Trial Update: A Study to Compare BMS-936558 to the Physician's Choice of Either Dacarbazine or Carboplatin and Paclitaxel in Advanced Melanoma Patients That Have Progressed Following Anti-CTLA-4 Therapy (CheckMate 037) [Phase 3]
Phase 3 trial comparing BMS-936558 (nivolumab) to physician's choice chemotherapy in advanced melanoma after anti-CTLA-4 therapy; trial comp…
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CLINICAL_TRIALS trial_result · 2017-03-16Clinical Trial Update: Vaccine Therapy in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Melanoma [Phase 1]
Phase 1 trial evaluating a vaccine therapy for advanced melanoma (stages IIB/IIC/III/IV) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Pilot Ipilimumab in Stage IV Melanoma Receiving Palliative Radiation Therapy [Phase 2]
A Phase 2 pilot trial evaluating ipilimumab in stage IV melanoma patients receiving palliative radiation therapy has completed with results …
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CLINICAL_TRIALS trial_result · 2017-03-09Clinical Trial Update: Combined BRAF-Targeted Therapy & Immunotherapy for Melanoma [Phase 2]
A Phase 2 trial evaluating a combination of BRAF-targeted therapy and immunotherapy for melanoma was terminated, with results posted in 2017…
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CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: Temozolomide and Everolimus in Treating Patients With Stage IV Melanoma That Cannot be Removed by Surgery [Phase 2]
Phase 2 trial evaluating the combination of temozolomide and everolimus in patients with stage IV melanoma that cannot be surgically removed…
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CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating a MEK inhibitor combined with a PI3K/mTOR inhibitor in subjects with locally advanced or metastatic solid tumors; r…
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CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: Carboplatin, Paclitaxel, and Bevacizumab With or Without Everolimus in Treating Patients With Metastatic Malignant Melanoma [Phase 2]
A Phase 2 trial evaluating carboplatin, paclitaxel, and bevacizumab with or without everolimus in metastatic malignant melanoma has complete…
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CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: Immuno-monitoring of Patients With Metastatic Melanoma (AJCC Stadium IV) Under Chemotherapy
This document notes the completion of a clinical trial evaluating immuno-monitoring in patients with metastatic melanoma (AJCC Stage IV) und…