Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: WoW - Single- vs Two-staged Excisions of Thin Melanoma [NA]
Clinical trial investigating single- versus two-staged excisions for thin melanoma; the study is currently recruiting in the Vastra Gotaland…
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CLINICAL_TRIALS research · 2025-03-03Clinical Trial Update: Camrelizumab Plus Apatinib and Temozolomide as Neoadjuvant in High Risk Acral Melanoma [Phase 2]
This clinical trial update describes a Phase 2 neoadjuvant study of camrelizumab plus apatinib and temozolomide in high-risk acral melanoma …
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Observational Study of Patients With Advanced Melanoma (Skin Cancer) to Assess if IOpener®-Melanoma Test Can Predict Response to Immunotherapy.
An observational clinical trial update evaluating whether the IOpener-Melanoma Test can predict response to immunotherapy in patients with a…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Precision Medicine for L/GCMN and Melanoma 1
This clinical trial update describes a precision medicine study for large/giant congenital melanocytic nevus (L/GCMN) and melanoma, and the …
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Safe Stop Ipilimumab-nivolumab (IPI-NIVO) Trial [NA]
Clinical trial update indicates the Ipilimumab-nivolumab (IPI-NIVO) combination trial for melanoma (stage III/IV) is currently recruiting at…
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CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: A Study to Compare Nivolumab Administered Subcutaneously vs Intravenous in Melanoma Participants Following Complete Resection [Phase 3]
Phase 3 trial comparing subcutaneous versus intravenous nivolumab in melanoma after complete resection has completed and posted results.
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Precision Medicine for L/GCMN and Melanoma 2
A clinical trial update indicates a precision medicine study for large/giant congenital melanocytic nevus and melanoma is currently recruiti…
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CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: Circulating Tumour DNA guidEd Therapy for Stage IIB/C mElanoma After surgiCal resecTION [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating circulating tumor DNA-guided therapy for stage IIB/C melanoma after surgical resection has been termin…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-PD-1 Compared to Anti-PD-1 Monotherapy as First-Line Treatment in Subjects With Unresectable/Metastatic Melanoma [Phase 3]
This update describes a Phase 3 trial evaluating BCD-217 (Nurulimab + Proglolimab) followed by anti-PD-1 therapy versus anti-PD-1 monotherap…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Understanding the Transition from Normal Melanocytes to Nevus to Melanoma
This clinical trial update describes a study on the transition from normal melanocytes to nevi to melanoma, sponsored by Fundacion Clinic pe…
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CLINICAL_TRIALS withdrawal · 2025-02-25Clinical Trial Update: Study of rSIFN-co for Patients With Advanced Solid Tumors [Phase 1]
A Phase 1 clinical trial of rSIFN-co for advanced solid tumors has been terminated, involving malignancies including melanoma, kidney cancer…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Ex VIvo DEtermiNed Cancer Therapy
An ongoing clinical trial for an Ex Vivo Determined Cancer Therapy is currently recruiting and spans multiple cancers, including bladder and…
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CLINICAL_TRIALS withdrawal · 2025-02-21Clinical Trial Update: QUILT-3.046: NANT Melanoma Vaccine: Combination Immunotherapy in Subjects With Melanoma Who Have Progressed On or After Chemotherapy and PD-1/PD-L1 Therapy [Phase 1, Phase 2]
The QUILT-3.046 trial evaluating the NANT Melanoma Vaccine in combination immunotherapy for melanoma patients who progressed after chemother…
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: Combination Therapy With Nivolumab and PD-L1/IDO Peptide Vaccine to Patients With Metastatic Melanoma [Phase 1, Phase 2]
A Phase 1/2 study evaluated the combination of nivolumab with a PD-L1/IDO peptide vaccine in patients with metastatic melanoma. The trial ha…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Identifying the Predictive Factors of Response to PD-1 or PD-L1 Antagonists [NA]
A clinical trial update aimed at identifying predictive factors of response to PD-1/PD-L1 inhibitors across multiple cancers, including mela…
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CLINICAL_TRIALS trial_result · 2025-02-18Clinical Trial Update: Interventional Study of INCB 99280 With Ipilimumab in Participants With Select Solid Tumors [Phase 1]
Phase 1 interventional trial evaluating INCB 99280 in combination with ipilimumab in select solid tumors has been terminated. The study, spo…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers [Phase 1, Phase 2]
Phase 1/2 trial update evaluating nivolumab plus ABI-009 (nab-rapamycin) in patients with advanced sarcoma and selected cancers, with result…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: BostonGene and Exigent Genomic INsight Study
Clinical trial update indicates that the BostonGene-Exigent Genomic INsight study is currently recruiting participants across indications in…
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CLINICAL_TRIALS other · 2025-02-14Clinical Trial Update: Fotemustine in Treating Patients With Metastatic Melanoma [Phase 2]
Phase 2 trial evaluating fotemustine for metastatic melanoma has been terminated.
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Targeted Radionuclide Therapy for Metastatic Melanoma [131I] ICF01012 [EARLY_Phase 1]
A Phase 1 early trial of the targeted radiopharmaceutical therapy [131I] ICF01012 for metastatic melanoma has completed.
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: A Study to Compare Quality of Life and Compliance in Patients Receiving High-dose Interferon Versus Pegylated Interferon in Patients With Surgically Resected Melanoma
A completed clinical trial comparing high-dose interferon with pegylated interferon in patients with surgically resected melanoma. The study…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: TIL-ACT After NMA Chemo with IL-2 and Nivo Rescue in Metastatic Melanoma (mMEL) [Phase 1]
Phase 1 clinical trial evaluating tumor-infiltrating lymphocyte adoptive cell therapy after non-myeloablative chemotherapy with IL-2 and niv…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Neoadjuvant PD-1 Blockade in Patients with Stage IIB/C Melanoma [Phase 2]
Phase 2 neoadjuvant trial evaluating PD-1 blockade in patients with stage IIB/C melanoma is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Relative Bioavailability Study of Subcutaneous Injection Versus Intravenous Infusion of Pembrolizumab (MK-3475) in Participants With Advanced Melanoma (MK-3475-555/KEYNOTE-555) [Phase 1]
Phase 1 study comparing subcutaneous vs intravenous pembrolizumab in adults with advanced melanoma evaluated relative bioavailability; resul…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: High Dose IL-2 in Combination With Anti-PD-1 to Overcome Anti-PD-1 Resistance in Metastatic Melanoma and Renal Cell Carcinoma [Phase 2]
Phase 2 trial evaluating high-dose interleukin-2 in combination with an anti-PD-1 therapy to overcome resistance in metastatic melanoma and …