Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: HS-IT101 Injection in the Treatment of Advanced Melanoma [Phase 1]
This clinical trial update reports Phase 1 testing of HS-IT101 injection for advanced melanoma, with enrollment ongoing by invitation.
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Pan-tumor MRD Study
Paradigm Health's Pan-tumor MRD study (NCT06605404) is currently recruiting across several solid tumor indications including bladder, esopha…
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: Tovorafenib (DAY101) or in Combination With Pimasertib for Participants With Melanoma and Other Solid Tumors [Phase 1]
A Phase 1 trial evaluating tovorafenib (DAY101) alone or with pimasertib for melanoma and other solid tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: Safety Study of a Dendritic Cell-based Cancer Vaccine in Melanoma [Phase 1]
A Phase 1 safety study evaluating a dendritic cell–based cancer vaccine in melanoma has been completed.
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma [Phase 2]
A Phase 2 clinical trial at Penn Medicine evaluating ipilimumab and nivolumab with or without hypofractionated radiotherapy in patients with…
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Safety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory Cancer [Phase 1]
Phase 1 safety study evaluating enoblituzumab (MGA271) in combination with pembrolizumab or MGA012 in patients with refractory cancers. Resu…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Study of Melanoma-Resistant PET Monitoring Based on Key Rate-limiting Enzymes for Fatty Acid Metabolism in Healthy Volunteers [NA]
A clinical trial from Xijing Hospital is evaluating a PET monitoring approach for melanoma based on key rate-limiting enzymes in fatty acid …
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Using an End-of-life Conversation Game to Engage Patients With Cancer in Advance Care Planning: Phase 2 [NA]
Phase 2 trial investigating an end-of-life conversation game to engage cancer patients in advance care planning; the study is currently acti…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Pembrolizumab Plus Bevacizumab for Treatment of Brain Metastases in Metastatic Melanoma or Non-small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial evaluating pembrolizumab in combination with bevacizumab for treatment of brain metastases in metastatic melanoma or non-small…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: TNFalpha and Interleukin 2 Coding Oncolytic Adenovirus TILT-123 During TIL Treatment of Advanced Melanoma [Phase 1]
Phase 1 trial evaluating TILT-123, an oncolytic adenovirus encoding TNF-α and interleukin-2, used with tumor-infiltrating lymphocyte therapy…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Omitting Therapeutic Lymph Node Dissection in Patients With Melanoma (Stage 3) and Major Pathological Response in the Index Lymph Node [NA]
A clinical trial update about omitting therapeutic lymph node dissection in stage 3 melanoma and observing major pathological response in th…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Oncolytic Adenovirus TILT-123 and Avelumab for Treatment of Solid Tumors Refractory to or Progressing After Anti-PD(L)1 [Phase 1]
Phase 1 trial evaluating the combination of oncolytic adenovirus TILT-123 with Avelumab in solid tumors that progressed after anti-PD-(L)1 t…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of APG-115 alone or with pembrolizumab in metastatic melanoma and other advanced solid tumors; the trial is currently active…
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CLINICAL_TRIALS withdrawal · 2025-08-07Clinical Trial Update: Aerosolized Sargramostim Added to Immunotherapy for the Treatment of Patients With Metastatic Melanoma to the Lung [Phase 1]
A Phase 1 trial evaluating aerosolized sargramostim in combination with immunotherapy for metastatic cutaneous melanoma with lung involvemen…
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases [NA]
This update notes a terminated clinical trial at the University of Southern California evaluating precise dynamic contrast-enhanced MRI (DCE…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 trial update for TRK-950 in combination with anti-cancer regimens in patients with advanced solid tumors; the study is active but no…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: A Model for Genetic Susceptibility: Melanoma
A clinical trial update from Memorial Sloan Kettering Cancer Center describes a model for genetic susceptibility in melanoma; the study is c…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanoma [Phase 1]
This Phase 1 clinical trial update assesses the safety of combining SBRT with an anti-PD-1 therapy (nivolumab) and an anti-IL-8 agent. The s…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Immunotherapy With Ipilimumab and Nivolumab Preceded or Not by a Targeted Therapy With Encorafenib and Binimetinib [Phase 2]
Phase 2 trial evaluating ipilimumab and nivolumab with or without encorafenib and binimetinib in unresectable stage III or stage IV melanoma…
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: MGC018 With or Without MGA012 in Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update reports results from the combination of MGC018 with or without MGA012 (pembrolizumab) in advanced solid tumors. T…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: MoleGazer Development Feasibility Study [NA]
A feasibility study named MoleGazer led by Oxford University Hospitals NHS Trust is in development for melanoma and benign moles, with statu…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Camu-Camu Prebiotic and Immune Checkpoint Inhibition in Patients With Non-small Cell Lung Cancer and Melanoma [Phase 1]
Phase 1 trial evaluating Camu-Camu prebiotic with immune checkpoint inhibition in patients with advanced non-small cell lung cancer and mela…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: eFLASH for Skin Lesions of Malignant Melanomas [NA]
This clinical trial update describes NCT06549439, evaluating eFLASH for skin lesions of metastatic melanoma, sponsored by the University of …
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: OH2 Injection in Solid Tumors [Phase 1, Phase 2]
This update notes a Phase 1/Phase 2 trial of OH2 Injection for solid tumors and melanoma, currently recruiting.
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: OH2 Injection in Melanoma [Phase 3]
OH2 Injection is in Phase 3 clinical trials for melanoma. The study is currently recruiting.