Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: An Open-label, Phase I Clinical Trial of Super1 TCR-T in NY-ESO-1-positive Patients With Advanced Solid Tumors [Phase 1]
Open-label Phase I trial of Super1 TCR-T therapy targeting NY-ESO-1 in patients with advanced solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma [Phase 2]
Phase 2 clinical trial evaluating binimetinib in combination with imatinib for unresectable KIT-mutant melanoma (Stage III-IV) is currently …
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Substudy 02A: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents in Participants With Programmed Cell-death 1 (PD-1) Refractory Melanoma (MK-3475-02A/KEYMAKER-U02) [Phase 1, Phase 2]
This clinical trial update reports the safety and efficacy of pembrolizumab in combination with investigational agents for PD-1 refractory m…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Study to Evaluate the Safety of Pembrolizumab in Participants With Unresectable or Metastatic Melanoma or Non-small Cell Lung Cancer in India (MK-3475-593/KEYNOTE-593) [Phase 4]
This Phase 4 trial evaluated the safety of pembrolizumab in patients with unresectable or metastatic melanoma or non-small cell lung cancer …
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors [Phase 1]
Phase 1 study of MEM-288 oncolytic virus in advanced solid tumors, evaluating MEM-288 alone and in combination with standard-of-care therapy…
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CLINICAL_TRIALS trial_result · 2025-08-28Clinical Trial Update: A Study to Evaluate AB308 in Combination With AB122 in Participants With Advanced Malignancies [Phase 1]
The Phase 1 study evaluating AB308 in combination with AB122 in participants with advanced malignancies has been completed.
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: IO102-IO103 in Combination With Pembrolizumab Versus Pembrolizumab Alone in Advanced Melanoma (IOB-013 / KN-D18) [Phase 3]
Phase 3 trial evaluating IO102-IO103 in combination with pembrolizumab versus pembrolizumab alone in advanced/metastatic/unresectable melano…
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CLINICAL_TRIALS trial_result · 2025-08-28Clinical Trial Update: TRAQinform Assessment of Immunotherapy Response
A completed clinical trial evaluating TRAQinform, an assessment tool for immunotherapy response in melanoma. The study is sponsored by AIQ S…
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CLINICAL_TRIALS trial_result · 2025-08-28Clinical Trial Update: Assessing the Tolerance and Clinical Benefit of feCAl tranSplantation in patientS With melanOma [Phase 2]
Phase 2 clinical trial update assessing tolerability and potential clinical benefit of fecal microbiota transplantation in patients with mel…
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: Immune Responses in Prostate, Lung, Melanoma and Breast Cancer Patients Following Stereotactic Body Radiotherapy (SBRT), Intensity Modulated Radiotherapy (IMRT) or Brachytherapy
Clinical trial update reporting immune responses in prostate, lung, melanoma, and breast cancer patients after SBRT, IMRT, or brachytherapy.
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: A Feasibility Study Utilizing Immune Recall to Increase Response to Checkpoint Therapy [Phase 1]
A Phase 1 trial update describes a feasibility study using immune recall to boost responses to checkpoint inhibitors in melanoma, currently …
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Statins and prOgression of Coronary atheRosclerosis in melanomA Patients Treated With chEckpoint inhibitorS
A clinical trial update shows that recruitment is ongoing to study whether statins affect progression of coronary atherosclerosis in melanom…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: A Study of ANV419 Alone or in Combination With Approved Treatment in Patients With Cutaneous Melanoma (OMNIA-1). [Phase 1, Phase 2]
The OMNIA-1 study evaluated ANV419 alone or with approved treatment in melanoma (including cutaneous/metastatic disease) in Phase 1/2; the t…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Cabozantinib and Pembrolizumab for Advanced Metastatic Melanoma [Phase 1, Phase 2]
This update reports the termination of a phase 1/2 trial evaluating cabozantinib in combination with pembrolizumab for advanced metastatic m…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: To Evaluate the Safety and Efficacy of ADP-TILIL7 in Patients With Locally Advanced or Metastatic Melanoma [Phase 1]
A Phase 1 clinical trial evaluating the safety and potential efficacy of ADP-TILIL7 in patients with locally advanced or metastatic melanoma…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: A Study of ST-1898 for Unresectable or Metastatic Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating ST-1898 for unresectable or metastatic melanoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: A Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination (FDC) in Previously Untreated Metastatic or Unresectable Melanoma [Phase 3]
Phase 3 clinical trial update evaluating a subcutaneous fixed-dose combination of nivolumab and relatlimab in previously untreated metastati…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Glycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01) [Phase 1, Phase 2]
Phase 1/2 trial results for GLIMMER-01, a bi-sialidase fusion protein from Palleon, tested across multiple solid tumors with results posted …
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid Tumors [Phase 1]
This Phase 1 trial assesses safety, tolerability, and preliminary efficacy of lomvastomig, a PD-1/TIM-3 bispecific antibody, in adults with …
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: E6201 and Dabrafenib for the Treatment of Central Nervous System Metastases From BRAF V600 Mutated Metastatic Melanoma [Phase 1]
Phase 1 study evaluating E6201 in combination with dabrafenib for central nervous system metastases from BRAF V600-mutated metastatic melano…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Flu Vaccine Responses in the Setting of Melanoma Treatment [Phase 4]
Phase 4 clinical trial update examining flu vaccine responses in patients undergoing melanoma treatment to understand vaccine effectiveness …
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: Combining PD-1 Blockade, CD137 Agonism and Adoptive Cell Therapy for Metastatic Melanoma [EARLY_Phase 1]
Early-phase trial evaluating a combination of PD-1 blockade, CD137 agonism, and adoptive cell therapy for metastatic melanoma has completed.
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Impact of Therapeutic Patient Education on the Toxicity of Immune Checkpoint Inhibitors in Oncology [NA]
A completed clinical trial evaluating whether therapeutic patient education can reduce the toxicity associated with immune checkpoint inhibi…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies [Phase 1]
Phase 1 dose-escalation and expansion study of intratumoral mRNA-2752 in advanced malignancies has completed, with expansion cohorts in seve…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A clinical trial update for SNS-101 (anti-VISTA) as monotherapy and in combination with cemiplimab in adults with advanced solid tumors, cur…