Mast Cell Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: (PATHFINDER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, in Patients With Advanced Systemic Mastocytosis [Phase 2]
Phase 2 PATHFINDER study evaluating avapritinib in advanced systemic mastocytosis and related subtypes has completed with results posted, as…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: (Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis [Phase 2]
Bezuclastinib is being studied in a Phase 2 trial for advanced systemic mastocytosis and related subtypes; recruitment is ongoing.
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CLINICAL_TRIALS withdrawal · 2024-06-28Clinical Trial Update: Managed Access Programs for PKC412, Midostaurin
This update indicates that Novartis' managed access programs for midostaurin (PKC412) are no longer available, impacting access for patients…
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CLINICAL_TRIALS trial_result · 2022-11-10Clinical Trial Update: GTB-3550 Tri-Specific Killer Engager (TriKE®) for High Risk Hematological Malignancies [Phase 1, Phase 2]
Phase 1/2 trial of GTB-3550 Tri-Specific Killer Engager (TriKE) for high-risk hematologic malignancies has been terminated; results posted i…
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CLINICAL_TRIALS trial_result · 2020-04-27Clinical Trial Update: Bioelectrical Impedance Measurement for Predicting Treatment Outcome in Patients With Newly Diagnosed Acute Leukemia [NA]
A completed clinical trial evaluating bioelectrical impedance measurements to predict treatment outcomes in newly diagnosed acute leukemia p…
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CLINICAL_TRIALS trial_result · 2019-01-29Clinical Trial Update: Brentuximab Vedotin in Treating Patients With Advanced Systemic Mastocytosis or Mast Cell Leukemia [Phase 2]
Phase 2 trial evaluating Brentuximab vedotin in advanced systemic mastocytosis or mast cell leukemia has completed and results have been pos…
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CLINICAL_TRIALS trial_result · 2018-09-20Clinical Trial Update: Ibrutinib in Treating Patients With Advanced Systemic Mastocytosis [Phase 2]
Phase 2 trial of ibrutinib in advanced systemic mastocytosis was terminated with posted results in 2018.
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FDA approval · 2018-06-21FDA Approved: RYDAPT — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approves a supplemental application for RYDAPT (midostaurin) from Novartis Pharmaceuticals; the update expands or modifies the drug’s la…
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CLINICAL_TRIALS trial_result · 2017-11-28Clinical Trial Update: Phase 2 Trial of Prophylactic Rituximab Therapy for Prevention of CGVHD [Phase 2]
Phase 2 trial evaluating rituximab as prophylaxis to prevent chronic graft-versus-host disease after allogeneic stem cell transplantation; t…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell Leukemia [Phase 2]
Phase 2 trial update evaluating the efficacy and safety of midostaurin in patients with aggressive systemic mastocytosis or mast cell leukem…
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CLINICAL_TRIALS trial_result · 2017-01-10Clinical Trial Update: Patient-Reported Outcome Questionnaire for Systemic Mastocytosis
A clinical trial update on a patient-reported outcome questionnaire for systemic mastocytosis, with the study status marked as completed.
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CLINICAL_TRIALS trial_result · 2015-07-09Clinical Trial Update: Phase 2 Midostaurin in Aggressive Systemic Mastocytosis and Mast Cell Leukemia [Phase 2]
Phase 2 trial update for midostaurin in aggressive systemic mastocytosis and mast cell leukemia has completed with results posted in 2015.