Marfan Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-12-22Clinical Trial Update: Randomized, Double-blind Study for the Evaluation of the Effect of Losartan Versus Placebo on Aortic Root Dilatation in Patients With Marfan Syndrome Under Treatment With Beta-blockers [Phase 3]
A Phase 3 randomized, double-blind study assessing losartan versus placebo on aortic root dilatation in Marfan syndrome patients already on …
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CLINICAL_TRIALS trial_result · 2020-12-28Clinical Trial Update: Hemodynamics Response to Upper Airway Obstruction in Marfan Syndrome [NA]
Clinical trial update on hemodynamic response to upper airway obstruction in Marfan syndrome; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-05-02Clinical Trial Update: Thoracic Aortic Dilatation Syndromes
This document reports that a clinical trial investigating thoracic aortic dilatation syndromes, including Marfan syndrome, has completed.
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CLINICAL_TRIALS research · 2018-04-05Clinical Trial Update: Studies of Heritable Disorders of Connective Tissue
A Clinical Trial Update from the National Institute on Aging reports completed studies on heritable connective tissue disorders, including E…
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Patients With MFS [Phase 3]
Phase 3 clinical trial comparing aliskiren to negative controls to assess its effect on aortic stiffness in patients with Marfan syndrome; t…
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CLINICAL_TRIALS research · 2017-03-15Clinical Trial Update: Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes
A completed clinical trial evaluated microRNAs as biomarkers for aortic aneurysm in hereditary aortopathy syndromes such as Marfan syndrome …
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CLINICAL_TRIALS research · 2017-01-05Clinical Trial Update: Development of a Blood Test for Marfan Syndrome
A clinical trial update describes the development of a blood test for Marfan syndrome. The update mentions Marfan syndrome and related disor…
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CLINICAL_TRIALS trial_result · 2016-12-20Clinical Trial Update: National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions
This clinical trial registry update notes the completion of an NHLBI-sponsored study on genetically triggered thoracic aortic aneurysms and …
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CLINICAL_TRIALS research · 2016-06-28Clinical Trial Update: Generation of Marfan Syndrome and Fontan Cardiovascular Models Using Patient-specific Induced Pluripotent Stem Cells
This clinical trial update describes efforts to generate patient-specific induced pluripotent stem cell–based cardiovascular models for Marf…
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CLINICAL_TRIALS trial_result · 2016-05-24Clinical Trial Update: Aortopathy in Persons With Bicuspid Aortic Valve, Turner and Marfan Syndrome
Clinical trial update on aortopathy in individuals with Turner syndrome, bicuspid aortic valve, and Marfan syndrome; the study has completed…
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CLINICAL_TRIALS withdrawal · 2016-02-05Clinical Trial Update: Circulating Transforming Growth Factor Beta (TGF-β) in Individuals With Marfan Syndrome [Phase 3]
Phase 3 trial investigating circulating transforming growth factor beta (TGF-β) in individuals with Marfan syndrome was withdrawn.
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CLINICAL_TRIALS trial_result · 2015-11-04Clinical Trial Update: Study of the Efficacy of Losartan on Aortic Dilatation in Patients With Marfan Syndrome [Phase 3]
Phase 3 study evaluating losartan for reducing aortic dilatation in Marfan syndrome has been terminated.
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CLINICAL_TRIALS research · 2015-06-09Clinical Trial Update: The Oxford Marfan Trial [Phase 2]
Update on a Phase 2 clinical trial for Marfan syndrome conducted by the University of Oxford. The current status of the trial is unknown.
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CLINICAL_TRIALS trial_result · 2015-04-01Clinical Trial Update: Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome [Phase 3]
Phase 3 trial comparing two medications aimed at slowing aortic root enlargement in Marfan syndrome has completed. Results have been posted.
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CLINICAL_TRIALS research · 2014-11-06Clinical Trial Update: Clinical Variability in Marfan Syndrome [NA]
This update notes the completion of a clinical trial studying clinical variability in Marfan syndrome.
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CLINICAL_TRIALS trial_result · 2014-09-01Clinical Trial Update: Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan Syndrome [Phase 3]
Phase 3 trial comparing losartan to atenolol in adults with Marfan syndrome, evaluating effects on aortic and cardiac muscle stiffness; resu…
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CLINICAL_TRIALS trial_result · 2012-07-12Clinical Trial Update: Losartan Versus Atenolol for the Treatment of Marfan Syndrome [Phase 2]
Phase 2 trial comparing losartan to atenolol for Marfan syndrome has completed.
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CLINICAL_TRIALS research · 2011-07-22Clinical Trial Update: Nebivolol Versus Losartan Versus Nebivolol+Losartan Against Aortic Root Dilation in Genotyped Marfan Patients [Phase 3]
Phase 3 clinical trial comparing nebivolol, losartan, and nebivolol plus losartan for preventing aortic root dilation in genotyped Marfan sy…
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CLINICAL_TRIALS trial_result · 2011-02-14Clinical Trial Update: Comparison of Medical Therapies in Marfan Syndrome. [Phase 4]
A Phase 4 clinical trial comparing medical therapies for Marfan syndrome has completed. The snippet does not provide outcome data.
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CLINICAL_TRIALS research · 2010-08-12Clinical Trial Update: Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan Syndrome [Phase 3]
Phase 3 clinical trial comparing atenolol and losartan to prevent progressive dilation of the aorta in Marfan syndrome.
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CLINICAL_TRIALS research · 2010-06-09Clinical Trial Update: A Randomized, Open-label, LOSARTAN Therapy on the Progression of Aortic Root Dilation in Patients With Marfan Syndrome [Phase 2]
A Phase 2 randomized, open-label study is evaluating losartan therapy to slow progression of aortic root dilation in patients with Marfan sy…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Study of Heritable Connective Tissue Disorders
The National Human Genome Research Institute completed a clinical trial studying heritable connective tissue disorders associated with aorti…
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CLINICAL_TRIALS trial_result · 2007-06-13Clinical Trial Update: Angiotensin Converting Enzyme Inhibitors in Marfan Syndrome [Phase 3]
A phase 3 clinical trial evaluating the use of angiotensin converting enzyme inhibitors in Marfan syndrome has completed.