Mantle Cell Lymphoma

CLINICAL_TRIALS trial_result · 2023-08-04

Clinical Trial Update: Bortezomib and Gemcitabine in Treating Patients With Relapsed Mantle Cell Lymphoma [Phase 2]

Phase 2 trial evaluating bortezomib plus gemcitabine in relapsed mantle cell lymphoma has completed.

CLINICAL_TRIALS trial_result · 2023-08-04

Clinical Trial Update: Bortezomib in Treating Patients With Mantle Cell Lymphoma [Phase 2]

Phase 2 trial update evaluating bortezomib in mantle cell lymphoma.

CLINICAL_TRIALS trial_result · 2023-07-25

Clinical Trial Update: Autologous Cells Derived Anti-CD19 CAR-Engineered T Cells With Concurrent BTK Inhibitor for B Cell Lymphoma [Phase 3]

Phase 3 trial investigating autologous anti-CD19 CAR-T cells given with a BTK inhibitor for B cell lymphomas, with an unspecified status.

CLINICAL_TRIALS trial_result · 2023-07-20

Clinical Trial Update: Gene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell Transplant [Phase 1, Phase 2]

This update reports results from a Phase 1/2 clinical trial of a gene therapy for HIV-related lymphomas in patients undergoing stem cell tra…

CLINICAL_TRIALS trial_result · 2023-07-13

Clinical Trial Update: Phase I/II, FIH, Dose Escalation Trial of TL-895 and Expansion of TL-895 Monotherapy and Combination Therapy With Navtemadlin in Tx-Naïve and R/R CLL/SLL Subjects [Phase 1, Phase 2]

Phase I/II trial update for TL-895 with navtemadlin in treatment-naïve and relapsed/refractory B cell malignancies, including CLL/SLL and re…

CLINICAL_TRIALS trial_result · 2023-06-09

Clinical Trial Update: High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant [Phase 2]

Phase 2 clinical trial evaluating high-dose cyclophosphamide, tacrolimus, and mycophenolate mofetil to prevent graft-versus-host disease in …

CLINICAL_TRIALS trial_result · 2023-06-05

Clinical Trial Update: A Study to Evaluate ICP-022 in Patients With R/R Mantle Cell Lymphoma (MCL) [Phase 1, Phase 2]

A clinical trial update for ICP-022 in relapsed/refractory mantle cell lymphoma across Phase 1 and Phase 2 stages.

CLINICAL_TRIALS trial_result · 2023-05-09

Clinical Trial Update: Ixazomib & Rituximab After Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma in Remission [Phase 1, Phase 2]

A clinical trial assessing ixazomib and rituximab after stem cell transplant in Mantle Cell Lymphoma in remission, spanning Phase 1 and Phas…

CLINICAL_TRIALS trial_result · 2023-03-20

Clinical Trial Update: Trial of Bortezomib, Cytarabine, and Dexamethasone in Mantle Cell Lymphoma [Phase 2]

Phase 2 trial investigating a combination of bortezomib, cytarabine, and dexamethasone in mantle cell lymphoma has completed.

CLINICAL_TRIALS trial_result · 2023-03-17

Clinical Trial Update: Study of OBINUTUZUMAB Combined to LENALIDOMIDE for the Treatment of Relapsed/Refractory Follicular and Aggressive B-cell Lymphoma [Phase 1, Phase 2]

Clinical trial updates the combination of obinutuzumab with lenalidomide for relapsed/refractory follicular and aggressive B-cell lymphomas,…

CLINICAL_TRIALS trial_result · 2023-03-16

Clinical Trial Update: TC-110 T Cells in Adults With Relapsed or Refractory Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia [Phase 1, Phase 2]

Phase 1/2 trial update for TC-110 T cells in adults with relapsed or refractory non-Hodgkin lymphoma or acute lymphoblastic leukemia (comple…

CLINICAL_TRIALS trial_result · 2023-02-16

Clinical Trial Update: Umbilical Cord Blood NK Cells, Rituximab, High-Dose Chemotherapy, and Stem Cell Transplant in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma [Phase 2]

Phase 2 trial evaluating Umbilical Cord Blood NK cells with Rituximab, high-dose chemotherapy, and stem cell transplant in recurrent or refr…

CLINICAL_TRIALS trial_result · 2023-02-09

Clinical Trial Update: Vincristine Sulfate Liposome Injection (Marqibo®), Bendamustine and Rituximab-Phase I Trial in Indolent B-cell Lymphoma [Phase 1]

Phase I trial evaluating a combination of Vincristine Sulfate Liposome Injection with Bendamustine and Rituximab in indolent B-cell lymphoma…

CLINICAL_TRIALS trial_result · 2023-01-31

Clinical Trial Update: Chemotherapy Plus Vaccination to Treat Mantle Cell Lymphoma [Phase 2]

Phase 2 trial evaluating chemotherapy plus vaccination for mantle cell lymphoma has completed; results posted in 2023.

CLINICAL_TRIALS trial_result · 2023-01-20

Clinical Trial Update: Ibrutinib in Treating Patients With Refractory or Relapsed Lymphoma After Donor Stem Cell Transplant [Phase 2]

Phase 2 trial evaluating ibrutinib in patients with refractory or relapsed lymphoma after donor stem cell transplant completed; results post…

CLINICAL_TRIALS trial_result · 2022-12-14

Clinical Trial Update: A Study of Copanlisib and Ibrutinib in Mantle Cell Lymphoma [Phase 1, Phase 2]

Phase 1/2 study evaluating copanlisib combined with ibrutinib in mantle cell lymphoma has completed with posted results.

CLINICAL_TRIALS trial_result · 2022-10-24

Clinical Trial Update: Ublituximab + Ibrutinib in Select B-cell Malignancies [Phase 1, Phase 2]

A phase 1/2 trial evaluating ublituximab in combination with ibrutinib for select B-cell malignancies has completed.

CLINICAL_TRIALS trial_result · 2022-09-15

Clinical Trial Update: Carfilzomib + Lenalidomide and Dexamethasone for BTK Inhibitors Relapsed-refractory or Intolerant MCL [Phase 2]

Phase 2 trial evaluating carfilzomib with lenalidomide and dexamethasone for mantle cell lymphoma that relapsed after or is intolerant to BT…

CLINICAL_TRIALS trial_result · 2022-09-13

Clinical Trial Update: Phase 2 Study of AT13387 (Onalespib) in ALK+ ALCL, MCL, and BCL-6+ DLBCL [Phase 2]

Phase 2 study of AT13387 (Onalespib) in ALK+ anaplastic large cell lymphoma, mantle cell lymphoma, and BCL-6+ diffuse large B-cell lymphoma …

CLINICAL_TRIALS trial_result · 2022-08-31

Clinical Trial Update: Genetically Modified T-Cell Therapy in Treating Patients With Advanced ROR1+ Malignancies [Phase 1]

Phase 1 trial update of a genetically modified T-cell therapy targeting ROR1 in advanced malignancies, with terminated status and posted res…

CLINICAL_TRIALS trial_result · 2022-08-17

Clinical Trial Update: Zanubrutinib-rituximab(ZR) in Patients With Newly Diagnosed Untreated Mantle Cell Lymphoma [Phase 2]

Phase 2 trial update for Zanubrutinib combined with rituximab in patients with newly diagnosed untreated mantle cell lymphoma.

CLINICAL_TRIALS trial_result · 2022-08-09

Clinical Trial Update: Phase II Study of Age-Adjusted Rituximab, Bendamustine, Cytarabine as Induction Therapy in Older Patients With MCL [Phase 2]

Phase II study evaluating age-adjusted rituximab, bendamustine, and cytarabine as induction therapy in older patients with mantle cell lymph…

CLINICAL_TRIALS trial_result · 2022-07-26

Clinical Trial Update: A Study of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib Given in Combination With Bendamustine and Rituximab in Patients With Newly Diagnosed Mantle Cell Lymphoma [Phase 3]

A Phase 3 trial evaluating the combination of ibrutinib with bendamustine and rituximab in newly diagnosed mantle cell lymphoma has complete…

CLINICAL_TRIALS trial_result · 2022-07-21

Clinical Trial Update: Study to Assess the Efficacy and Safety of Ublituximab + Umbralisib With or Without Bendamustine and Umbralisib Alone in Patients With Previously Treated Non-Hodgkins Lymphoma [Phase 2, Phase 3]

Phase 2/3 trial assessing ublituximab + umbralisib with or without bendamustine, and umbralisib alone, in previously treated non-Hodgkin lym…

CLINICAL_TRIALS trial_result · 2022-05-25

Clinical Trial Update: Laboratory Treated T Cells in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma, or Acute Lymphoblastic Leukemia [Phase 1, Phase 2]

Phase 1/2 trial evaluating laboratory-treated T cells in relapsed or refractory B-cell malignancies and acute lymphoblastic leukemia.

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