Mantle Cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-18Clinical Trial Results: Study of Brexucabtagene Autoleucel (KTE-X19) in Participants With Relapsed/Refractory Mantle Cell Lymphoma (Cohort 3) [Phase 2]
Phase 2 trial results of Brexucabtagene Autoleucel (KTE-X19) show outcomes in relapsed/refractory mantle cell lymphoma.
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CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Results: Phase II Trial of Venetoclax and Rituximab as Initial Therapy in Older Patients With Mantle Cell Lymphoma [Phase 2]
Phase II trial results of venetoclax plus rituximab as initial therapy in older patients with mantle cell lymphoma were reported.
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: The Efficacy and Safety of Sonrotoclax, Zanubrutinib Combined With Obinutuzumab in MCL [Phase 1]
A Phase 1 trial evaluating the combination of Sonrotoclax, Zanubrutinib, and Obinutuzumab in intermediate-to-high-risk Mantle Cell Lymphoma,…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL) [Phase 3]
Phase 3 clinical trial evaluating Sonrotoclax plus Zanubrutinib versus placebo plus Zanubrutinib in adults with relapsed/refractory mantle c…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Copanlisib and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of Copanlisib and Venetoclax for relapsed or refractory mantle cell lymphoma, currentl…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma [Phase 2]
A Phase 2 study evaluating glofitamab with pirtobrutinib for relapsed or refractory mantle cell lymphoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies [Phase 1]
NX-5948 is being studied in a Phase 1 trial for adults with relapsed/refractory B-cell malignancies; the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: SynKIR-310 for Relapsed/Refractory B-NHL [Phase 1]
Phase 1 trial update for SynKIR-310 in relapsed/refractory B-cell non-Hodgkin lymphoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Long-term Follow-up Study of Allogeneic Gamma Delta (γδ) CAR T Cells
This document provides a long-term follow-up update on allogeneic gamma delta CAR T cell therapy. The trial covers several B-cell lymphoma i…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma [Phase 2]
This document reports an ongoing Phase II trial assessing the combination of palbociclib and ibrutinib in mantle cell lymphoma, with the stu…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Long-term Follow-up Study for Patients Treated With CLBR001 CAR-T [Phase 1]
This clinical trial update reports long-term follow-up results from a Phase 1 study of CLBR001 CAR-T cells in relapsed/refractory B-cell lym…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Expanded Access Study for the Treatment of Patients With Commercially Out-of-Specification Brexucabtagene Autoleucel
Expanded access study for brexucabtagene autoleucel (Tecartus) for mantle cell lymphoma and acute lymphoblastic leukemia is currently availa…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Study of VAY736 as Single Agent and in Combination With Select Antineoplastic Agents in Patients With Non-Hodgkin Lymphoma [Phase 1]
Phase 1 study update for VAY736 in non-Hodgkin lymphoma shows the trial status as terminated, evaluating VAY736 alone and in combination wit…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Ibrutinib in Combination With Rituximab in Patients With Indolent Clinical Forms of MCL [Phase 2]
Phase 2 trial evaluating ibrutinib in combination with rituximab for indolent mantle cell lymphoma is currently active and not recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission [Phase 3]
Phase 3 trial evaluating whether adding autologous stem cell transplant to rituximab improves outcomes in patients with minimal residual dis…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: ALX148, Rituximab and Lenalidomide for the Treatment of Indolent and Aggressive B-cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
A Phase 1/2 study evaluating ALX148 in combination with Rituximab and Lenalidomide for various B-cell non-Hodgkin lymphomas, with the trial …
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: A Study of Voruciclib Alone or in Combination With Venetoclax in Subjects With B-Cell Malignancies or AML [Phase 1]
Phase 1 trial update for voruciclib alone or with venetoclax in various B-cell malignancies and acute myeloid leukemia; the study has been t…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Treatment by a Bispecific CD3xCD20 Antibody for Relapse/Refractory Lymphomas After CAR T-cells Therapy [Phase 2]
Phase 2 clinical trial evaluating a CD3xCD20 bispecific antibody for relapse/refractory B-cell non-Hodgkin lymphomas after CAR-T therapy has…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: Lenalidomide and Combination Chemotherapy (DA-EPOCH-R) in Treating Patients With MYC-Associated B-Cell Lymphomas [Phase 1, Phase 2]
Phase 1/2 study evaluating the combination of lenalidomide with DA-EPOCH-R in MYC-associated B-cell lymphomas has completed, and results hav…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Ixazomib Citrate and Rituximab in Treating Patients With Indolent B-cell Non-Hodgkin Lymphoma [Phase 2]
Phase 2 trial evaluating ixazomib citrate with rituximab in indolent B-cell non-Hodgkin lymphoma has posted results.
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Study of BGB-10188 as Monotherapy, and in Combination With Zanubrutinib, and Tislelizumab [Phase 1, Phase 2]
BeiGene announced completion and posted results for a Phase 1/2 study of BGB-10188 as monotherapy and in combination with zanubrutinib and t…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: EDOCH Alternating With DHAP for New Diagnosed Younger MCL [Phase 4]
Phase 4 clinical trial evaluating EDOCH alternating with DHAP for newly diagnosed younger patients with Mantle Cell Lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Dose Escalation/Dose Expansion Study of PRGN-3007 UltraCAR-T Cells in Patients With Advanced Hematologic and Solid Tumor Malignancies [Phase 1]
Phase 1 dose-escalation and expansion study of PRGN-3007 UltraCAR-T cells in patients with advanced hematologic and solid tumors has complet…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Zanubrutinib (BGB-3111) in Participants With Previously Treated B-Cell Lymphoma Intolerant of Prior Bruton Tyrosine Kinase Inhibitor (BTKi) Treatment [Phase 2]
This update summarizes a Phase 2 trial of zanubrutinib (BGB-3111) in participants with previously treated B-cell lymphomas intolerant to pri…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: A Study of Oral LOXO-305 in Patients With Previously Treated CLL/SLL or NHL [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial of the oral BTK inhibitor LOXO-305 (pirtobrutinib) in patients with previously treated chronic lymphocy…