Mantle Cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-07-22Clinical Trial Update: Long-term Follow-up Study in Patients Previously Treated With a Mustang Bio CAR-T Cell Investigational Product.
A long-term follow-up update on patients previously treated with Mustang Bio's CAR-T cell investigational product; the trial has been termin…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: A Study of MS-553 in Patients With Relapsed or Refractory B-cell Lymphoma [Phase 1, Phase 2]
MS-553 trial in relapsed/refractory B-cell lymphomas was terminated after Phase 1/2 studies.
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: A Study of LOXO-305 in Chinese Participants With Blood Cancer (Including Lymphoma and Chronic Leukemia) [Phase 2]
Phase 2 clinical trial update on LOXO-305 (pirtobrutinib) in Chinese participants with B-cell malignancies, with results posted on July 16, …
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: Study Evaluating the Safety and Pharmacokinetics of JCAR017 in B-cell Non-Hodgkin Lymphoma (TRANSCEND-NHL-001) [Phase 1]
Phase 1 study evaluating safety and pharmacokinetics of JCAR017 in B-cell non-Hodgkin lymphomas has completed.
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: A Phase Ib Study of YY-20394 in Participants With B-cell Hematologic Malignancies [Phase 1]
Phase Ib study of YY-20394 in participants with B-cell hematologic malignancies has completed, evaluating safety and preliminary activity ac…
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Study of STRO-001, an Anti-CD74 Antibody Drug Conjugate, in Patients With Advanced B-Cell Malignancies [Phase 1]
Phase 1 study of STRO-001, an anti-CD74 antibody-drug conjugate, in advanced B-cell malignancies has been completed.
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: Evaluating the Feasibility of a Digital Health Coaching Program for Individuals Following CAR T Therapy [NA]
A completed clinical trial evaluating the feasibility of a digital health coaching program for individuals after CAR T-cell therapy.
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: A Study to Assess Safety of ImbruvicaTM in Indian Participants With Chronic Lymphocytic Leukemia or Mantle Cell Lymphoma Who Have Received at Least One Prior Therapy or Chronic Lymphocytic Leukemia With 17p Deletion [Phase 4]
Phase 4 safety study of ibrutinib (Imbruvica) in Indian participants with chronic lymphocytic leukemia or mantle cell lymphoma who have rece…
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CLINICAL_TRIALS trial_result · 2024-03-22Clinical Trial Update: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 562 in Subjects With r/r Diffuse Large B-cell Lymphoma, Mantle Cell Lymphoma, or Follicular Lymphoma [Phase 1]
Phase 1 trial evaluating AMG 562 in relapsed/refractory DLBCL, MCL, or follicular lymphoma was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Ibrutinib After Intensive Induction in Treating Patients With Previously Untreated Mantle Cell Lymphoma [Phase 2]
Phase 2 trial evaluating ibrutinib after intensive induction in previously untreated mantle cell lymphoma patients; status unavailable with …
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Idelalisib Post Allogeneic Hematopoietic Stem Cell Transplant (HSCT) in B Cell Derived Malignancies [Phase 1]
Phase 1 clinical trial update examining idelalisib after allogeneic HSCT in B-cell malignancies; the study is terminated with results posted…
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CLINICAL_TRIALS trial_result · 2024-02-12Clinical Trial Update: Acalabrutinib and Rituximab in Elderly Patients With Untreated Mantle Cell Lymphoma [Phase 2]
A Phase 2 trial evaluating acalabrutinib in combination with rituximab for elderly patients with untreated mantle cell lymphoma is ongoing (…
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CLINICAL_TRIALS trial_result · 2024-02-06Clinical Trial Update: Safety and Efficacy Study of Loncastuximab Tesirine + Ibrutinib in Diffuse Large B-Cell or Mantle Cell Lymphoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating loncastuximab tesirine in combination with ibrutinib for diffuse large B-cell lymphoma and mantle cell lymphoma w…
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy [Phase 2]
Phase 2 clinical trial update for MGTA-456 in high-risk hematologic malignancies; results were posted in 2024 and the study is currently act…
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CLINICAL_TRIALS trial_result · 2024-01-26Clinical Trial Update: Dose Finding Study of Ibrutinib Plus Lenalidomide / Rituximab in Relapsed or Refractory Mantle Cell Lymphoma [Phase 1]
Phase 1 dose-finding study evaluating the combination of ibrutinib, lenalidomide, and rituximab in relapsed or refractory mantle cell lympho…
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CLINICAL_TRIALS trial_result · 2024-01-23Clinical Trial Update: Phase II Study of Bendamustine and Rituximab Plus Venetoclax in Untreated Mantle Cell Lymphoma Over 60 Years of Age [Phase 2]
This clinical trial update presents results from a Phase II study evaluating a triplet regimen of bendamustine, rituximab, and venetoclax in…
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CLINICAL_TRIALS trial_result · 2024-01-08Clinical Trial Update: A Study of Ixazomib and Ibrutinib in Relapsed/Refractory Mantle Cell Lymphoma [Phase 1, Phase 2]
A clinical trial evaluating ixazomib in combination with ibrutinib in relapsed/refractory mantle cell lymphoma has completed (Phase 1/Phase …
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CLINICAL_TRIALS trial_result · 2023-11-24Clinical Trial Update: CD19-targeted CAR T Cells for Relapsed and Refractory (R/R) Mantle Cell Lymphoma [Phase 2]
A Phase 2 clinical trial investigating CD19-targeted CAR T cells for relapsed/refractory mantle cell lymphoma is active not recruiting.
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: Acalabrutinib, Umbralisib, and Ublituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma [Phase 2]
Phase 2 trial update of a three-drug combination (acalabrutinib, umbralisib, and ublituximab) for previously untreated mantle cell lymphoma;…
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CLINICAL_TRIALS trial_result · 2023-10-25Clinical Trial Update: Evaluating Different Doses of Orelabrutinib in MCL [Phase 2]
A Phase 2 trial update evaluating different doses of orelabrutinib in Mantle Cell Lymphoma.
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Clinical Trial of Ublituximab and Umbralisib With CHOP (U2-CHOP) Followed by U2 Maintenance (U2-CHOP-U2) in Previously Untreated Mantle Cell Lymphoma (MCL) [Phase 1, Phase 2]
A clinical trial evaluating Ublituximab and Umbralisib with CHOP followed by U2 maintenance in newly diagnosed mantle cell lymphoma was term…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Allo HSCT Using RIC for Hematological Diseases [Phase 2]
Phase 2 trial evaluating allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning for various hematologic dise…
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CLINICAL_TRIALS trial_result · 2023-08-21Clinical Trial Update: ABT-199 & Ibrutinib in Mantle Cell Lymphoma (AIM) [Phase 2]
A Phase 2 clinical trial update evaluating ABT-199 and Ibrutinib for Mantle Cell Lymphoma.
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CLINICAL_TRIALS trial_result · 2023-08-16Clinical Trial Update: Sequential Chemo-Radioimmunotherapy Followed by Autologous Transplantation for Patients With Untreated Advanced Stage Mantle Cell Lymphoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating sequential chemo-radiotherapy followed by autologous transplantation in untreated advanced mantle cell l…
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CLINICAL_TRIALS trial_result · 2023-08-04Clinical Trial Update: A Phase II Study of AT7519M, a CDK Inhibitor, in Patients With Relapsed Mantle Cell Lymphoma [Phase 2]
Phase II study of AT7519M, a CDK inhibitor, in patients with relapsed mantle cell lymphoma has completed.