Mantle Cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Acalabrutinib and Rituximab in Previously Untreated Mantle Cell Lymphoma [Phase 2]
A Phase 2 clinical trial evaluating acalabrutinib plus rituximab as first-line treatment for mantle cell lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Autologous CD19 CAR-T Cell Therapy (SYNCAR-001) + Orthogonal IL-2 (STK-009) in Subjects With CD19+ Hematologic Malignancies [Phase 1]
Phase 1 study evaluating autologous CD19 CAR-T cell therapy SYNCAR-001 with orthogonal IL-2 STK-009 in CD19-positive hematologic malignancie…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: CD70-targeted immunoPET Imaging of Malignant Cancers [NA]
A clinical trial evaluating CD70-targeted immunoPET imaging in multiple cancers is currently recruiting, including renal cell carcinoma, dif…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: A Study of Patients With Relapsed/Refractory Mantle Cell Lymphoma Treated With Lisocabtagene Maraleucel in the Post-Marketing Setting
A post-marketing study evaluating lisocabtagene maraleucel for relapsed/refractory mantle cell lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: A Clinical Trial of BP1002 in Patients With Advanced Lymphoid Malignancies [Phase 1]
Phase 1 clinical trial update for BP1002 in advanced lymphoid malignancies across several B-cell and T-cell lymphomas; trial status is activ…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Acalabrutinib With R-CHOP in Previously Untreated Mantle Cell Lymphoma [Phase 2]
This clinical trial update reports Phase 2 evaluation of acalabrutinib in combination with R-CHOP as first-line treatment for mantle cell ly…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Sequential Treatment of CD19 CARNK and 7x19 CAR-T in R/R B Cell Lymphoma [Phase 1]
A Phase 1 trial assessing sequential administration of CD19 CAR-NK cells followed by 7x19 CAR-T cells in relapsed/refractory B-cell lymphoma…
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CLINICAL_TRIALS research · 2025-02-03Clinical Trial Update: Clinical Outcomes of Chronic Lymphocytic Leukemia (CCL) and Mantle Cell Lymphoma (MCL) Participants Treated With Ibrutinib: A Medical Chart Review From India
A retrospective medical chart review from India evaluating outcomes of chronic lymphocytic leukemia and mantle cell lymphoma patients treate…
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial update on locally manufactured CAR T-cell products for multiple B-cell malignancies, including B-cell lymphoma and B-…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: Real-world Study of Acalabrutinib
A real-world study of acalabrutinib sponsored by Ruijin Hospital is enrolling by invitation, investigating its use in mantle cell lymphoma a…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: A Prospective, Single-Center Study Evaluating the Efficacy and Safety of Glofitamab Combined With Orelabrutinib and Bortezomib in Patients With High-Risk Mantle Cell Lymphoma [Phase 2]
A prospective, single-center Phase 2 study assessing the efficacy and safety of combining Glofitamab with Orelabrutinib and Bortezomib in hi…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: Study to Evaluate the Safety and Preliminary Efficacy of Ibrutinib and Pembrolizumab in Patients With Chronic Lymphocytic Leukemia (CLL) or Mantle Cell Lymphoma (MCL) [Phase 1, Phase 2]
Early-phase study evaluating the safety and preliminary efficacy of combining ibrutinib with pembrolizumab in chronic lymphocytic leukemia o…
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: Clinical Trial to Assess The Efficacy and Safety of the Combination of Tisagenlecleucel And Ibrutinib in Mantle Cell Lymphoma [Phase 2]
A Phase 2 clinical trial update describing the investigation of combining tisagenlecleucel with ibrutinib for mantle cell lymphoma, currentl…
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: Zanubrutinib and Rituximab Followed by R-DHAOx Then Maintenance with Zanubrutinib for Newly-Diagnosed MCL [Phase 2]
Phase 2 trial investigating zanubrutinib and rituximab followed by R-DHAOx and zanubrutinib maintenance for newly diagnosed mantle cell lymp…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: CAR T Cells in the Treatment of Refractory and Relapsed CD19+ B Cell Neoplasms [Phase 1]
Phase 1 trial of CD19-targeted CAR T cells for refractory/relapsed CD19-positive B-cell neoplasms (ALL, mantle cell lymphoma, diffuse large …
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CLINICAL_TRIALS research · 2024-09-04Clinical Trial Update: A Multicenter, Prospective, Phase II Study of Zanubrutinib for Maintenance in Patients With Mantle Cell Lymphoma [Phase 2]
A multicenter Phase II clinical trial evaluating zanubrutinib as maintenance therapy in patients with mantle cell lymphoma is currently recr…
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Optimizing ctDNA-based MRD Assessment in DLBCL, MCL, and FL Patients Undergoing CAR Therapy
This clinical trial update from Adaptive Biotechnologies aims to optimize ctDNA-based minimal residual disease assessment in patients with f…
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Significance of Duration of Maintenance Therapy With Rituximab in Non-Hodgkin Lymphomas [Phase 3]
This Phase 3 trial update discusses how the duration of rituximab maintenance therapy may affect outcomes in various non-Hodgkin lymphomas, …
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CLINICAL_TRIALS research · 2024-07-29Clinical Trial Update: Treatment of Patients With Relapsed or Refractory CD19+ Lymphoid Disease With T Cells Expressing a Third-generation CAR [Phase 1, Phase 2]
A Phase 1/2 clinical trial at University Hospital Heidelberg is evaluating third-generation CD19-directed CAR T cells in relapsed or refract…
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CLINICAL_TRIALS research · 2024-07-11Clinical Trial Update: Bendamustine and Rituximab With or Without Orelabrutinib in MCL Treatment [Phase 3]
A Phase 3 trial is evaluating bendamustine and rituximab with or without orelabrutinib in mantle cell lymphoma. The study is currently recru…
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CLINICAL_TRIALS research · 2024-07-10Clinical Trial Update: Whole-body Diffusion-weighted Magnetic Resonance Imaging for Staging and Treatment Prediction of Lymphoma [NA]
This document provides an update on a clinical trial evaluating whole-body diffusion-weighted MRI for staging and predicting treatment respo…
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CLINICAL_TRIALS research · 2024-07-01Clinical Trial Update: CAR-T-cell Treatment for Untreated High Risk MANtle Cell Lymphoma [Phase 2]
A Phase 2 clinical trial is evaluating a CAR-T cell therapy for untreated high-risk mantle cell lymphoma and is currently recruiting.
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: Efficacy of Polatuzumab, Bendamustine and Rituximab in Patients With Relapsed/ Refractory Mantle Cell Lymphoma [Phase 2]
Phase 2 clinical trial evaluating the efficacy of a combination of polatuzumab vedotin, bendamustine, and rituximab in relapsed/refractory m…
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: This is a Phase II, Open-label, Multicentre Study of Zanubrutinib-containing Regimens in Patients With Newly Diagnosed Mantle Cell Lymphoma [Phase 2]
This is a Phase II, open-label multicenter study evaluating regimens containing zanubrutinib in newly diagnosed mantle cell lymphoma. The tr…
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CLINICAL_TRIALS research · 2019-02-01Clinical Trial Update: A Phase I Study of AC0010 in Patients With CLL/ SLL, MCL, DLBCL and Other NHL [Phase 1]
Phase I trial evaluating AC0010 in patients with CLL/SLL, mantle cell lymphoma, diffuse large B-cell lymphoma, and other non-Hodgkin lymphom…