Mantle Cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Pilot "Window-3" Study of Acalabrutinib Plus Rituximab Followed by Brexucabtagene Autoleucel Therapy in Patients With Previously Untreated High-risk Mantle Cell Lymphoma [EARLY_Phase 1]
Clinical trial update describing a Phase 1 study of acalabrutinib plus rituximab followed by brexucabtagene autoleucel in previously untreat…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study
A Mayo Clinic-sponsored clinical trial (HALT) is evaluating strategies to manage hypertension and prevent cardiovascular adverse events in p…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin Lymphoma [Phase 1]
Phase 1 clinical trial from City of Hope evaluating CMV-specific CD19-CAR T-cells with CMV-MVA Triplex vaccine after stem cell transplantati…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating CAR-20/19-T cells in relapsed or refractory B-cell malignancies, including multiple non-Hodgkin lymphoma…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies [Phase 1]
A Phase 1 clinical trial is investigating LV20.19 CAR T-cells in combination with pirtobrutinib for relapsed or refractory B-cell malignanci…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: BRAZAN: A Randomized Phase 2 Study of Bendamustine, Rituximab, Cytarabine (AraC) Induction With Zanubrutinib (BRAZAN) Followed by Zanubrutinib/Rituximab +/- Sonrotoclax Maintenance in Treatment-Naïve Mantle Cell Lymphoma [Phase 2]
BRAZAN is a Phase 2 randomized trial evaluating induction with Bendamustine, Rituximab, Cytarabine plus Zanubrutinib, followed by Zanubrutin…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Study of APG-3288 in Relapsed/Refractory Blood Cancers [Phase 1]
Phase 1 study of APG-3288 in relapsed/refractory hematologic cancers; the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients With Newly Diagnosed High Risk Mantle Cell Lymphoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a quadruple regimen of glofitamab, obinutuzumab, venetoclax, and lenalidomide for newly diagnosed high…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Ibrutinib and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or Older Patients With Newly Diagnosed Mantle Cell Lymphoma [Phase 2]
Phase 2 clinical trial evaluating the combination of ibrutinib and rituximab in relapsed or refractory mantle cell lymphoma and in older pat…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL [Phase 3]
Phase 3 study comparing bendamustine-rituximab (BR) alone versus BR plus acalabrutinib in previously untreated mantle cell lymphoma; the tri…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: This Clinical Trial is a Single-arm, Non-randomized Pilot Trial to Determine the Safety of Administering Autologous Anti-C19 Cells (ARI-0001) and the Feasibility of Local CAR-T Cell Production in Patients Over 18 Years of Age With Relapsed/Refractory (R/R) CD19+ Hematologic Malignancies, Including R [NA]
A single-arm, non-randomized pilot trial to evaluate the safety of autologous anti-CD19 CAR-T cells (ARI-0001) and the feasibility of local …
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Venetoclax and Acalabrutinib in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma [Phase 2]
Phase 2 clinical trial update evaluating the combination of venetoclax and acalabrutinib for relapsed or refractory mantle cell lymphoma, in…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies. [Phase 1]
A Phase 1 clinical trial evaluating oral LP-168 in relapsed or refractory B-cell malignancies is recruiting. Target conditions include CLL/S…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Study of SGR-1505 in Mature B-Cell Neoplasms [Phase 1]
Schrödinger's SGR-1505 is being evaluated in a Phase 1 trial across multiple mature B-cell neoplasms and is currently recruiting. The study …
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies [Phase 1]
Phase 1 clinical trial from Mayo Clinic is evaluating BAFFR-based CAR-T cells with lymphodepletion (fludarabine and cyclophosphamide) for re…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Ibrutinib, Rituximab, Venetoclax, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma [Phase 2]
Phase 2 clinical trial evaluating Ibrutinib, Rituximab, Venetoclax, and combination chemotherapy in newly diagnosed mantle cell lymphoma.
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Phase II Study of Glofitamab With Venetoclax +/- Zanubrutinib in High-risk Mantle-cell Lymphoma [Phase 2]
This clinical trial update outlines a Phase II study evaluating glofitamab with venetoclax, with or without zanubrutinib, in high-risk mantl…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: This is a Phase 1 Study to Evaluate the Safety of LTZ-301 in Patients With Non-Hodgkin Lymphoma [Phase 1]
Phase 1 clinical trial assessing the safety of LTZ-301 in patients with various forms of non-Hodgkin lymphoma, currently recruiting.
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: CONFIRM: Magnetic Resonance Guided Radiation Therapy [NA]
ClinicalTrials.gov study CONFIRM is evaluating magnetic resonance guided radiation therapy and is currently recruiting for several cancers, …
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Acalabrutinib and Obinutuzumab for the Treatment of Previously Untreated Follicular Lymphoma or Other Indolent Non-Hodgkin Lymphomas [Phase 2]
A Phase 2 clinical trial evaluating the combination of acalabrutinib and obinutuzumab as initial therapy for previously untreated follicular…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Study of Rocbrutinib Versus Investigator's Choice of BTK Inhibitors in Patients With Relapsed or Refractory Mantle Cell Lymphoma [Phase 3]
Phase 3 trial evaluating Rocbrutinib versus investigator's choice of BTK inhibitors in relapsed or refractory Mantle Cell Lymphoma; the stud…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Glofitamab Plus Ibrutinib With Obinutuzumab for the Treatment of Patients With Mantle Cell Lymphoma, IGNITE MCL Trial [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating glofitamab plus ibrutinib with obinutuzumab for mantle cell lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Registry Platform Hematologic Malignancies (RUBIN) - Extension of Tumor Registry Lymphatic Neoplasms
Clinical trial registry update for the RUBIN platform extension focusing on hematologic malignancies. It is currently recruiting for conditi…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy [Phase 3]
Phase 3 clinical trial evaluating a digital health intervention for self-management and telemonitoring in CAR-T therapy is currently recruit…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Relmacabtagene Autoleucel Combined With Sintilimab for Relapsed/Refractory B-cell Lymphoma [Phase 2]
Phase 2 clinical trial update evaluating Relmacabtagene autoleucel in combination with sintilimab for relapsed/refractory B-cell lymphomas; …