Malignant Pleural Mesothelioma
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Sign up freeTop drugs studied for this disease
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FDA approval · 2017-08-03FDA Approved: GEMCITABINE — Original Application (Accord Healthcare Inc.)
FDA approved Accord Healthcare's gemcitabine injectable drug as an original application, providing a generic version of the anticancer agent…
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CLINICAL_TRIALS trial_result · 2017-06-09Clinical Trial Update: Intrapleural Administration of HSV1716 to Treat Patients With Malignant Pleural Mesothelioma. [Phase 1, Phase 2]
A Phase 1/2 clinical trial assessed intrapleural administration of HSV-1716 for malignant pleural mesothelioma; the study has completed.
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CLINICAL_TRIALS research · 2017-04-07Clinical Trial Update: MesomiR 1: A Phase I Study of TargomiRs as 2nd or 3rd Line Treatment for Patients With Recurrent MPM and NSCLC [Phase 1]
Phase I study of MesomiR-1 (TargomiRs) for recurrent malignant pleural mesothelioma and non-small cell lung cancer; the trial status is comp…
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Phase II Study of Six Hours Low Dose Gemcitabine Plus Cisplatin in the Treatment for Advanced Pleural Mesothelioma [Phase 2]
Clinical trial update on a Phase II study of six-hour low-dose gemcitabine plus cisplatin for advanced malignant pleural mesothelioma.
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: Standard Chemotherapy With of Without Axitinib in Malignant Mesothelioma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating adding axitinib to standard chemotherapy for malignant pleural mesothelioma; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-02-09Clinical Trial Update: A Study of Cetuximab Combined With Cisplatin or Carboplatin/Pemetrexed as First Line Treatment in Patients With Malignant Pleural Mesothelioma. [Phase 2]
Phase 2 study evaluating cetuximab with cisplatin or carboplatin/pemetrexed as first-line therapy for malignant pleural mesothelioma has com…
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CLINICAL_TRIALS trial_result · 2017-01-30Clinical Trial Update: Placebo Controlled Study of VS-6063 in Subjects With Malignant Pleural Mesothelioma [Phase 2]
A Phase 2 placebo-controlled trial of VS-6063 (defactinib) in malignant pleural mesothelioma was terminated.
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CLINICAL_TRIALS trial_result · 2017-01-23Clinical Trial Update: Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesothelioma [Phase 1]
Phase 1 trial evaluating cytoprotective strategies with amifostine and sodium thiosulfate alongside Cisplatin and Gemcitabine in patients un…
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CLINICAL_TRIALS withdrawal · 2016-12-07Clinical Trial Update: Concurrent Pemetrexed/Cisplatin With Pleural Intensity Modulated Radiation Therapy for Patients With Unresectable Malignant Pleural Mesothelioma [Phase 1]
The Phase 1 trial evaluating concurrent pemetrexed/cisplatin with pleural intensity-modulated radiation therapy for unresectable malignant p…
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CLINICAL_TRIALS research · 2016-11-21Clinical Trial Update: uPAR-PET for Prognostication in Patients With Non-small Cell Lung Cancer, Malignant Pleural Mesothelioma and Large Cell Neuroendocrine Carcinoma of the Lung [Phase 2]
Clinical trial update describing Phase 2 evaluation of uPAR-PET imaging as a prognostic tool in patients with Non-small cell lung cancer, ma…
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CLINICAL_TRIALS trial_result · 2016-09-09Clinical Trial Update: Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate [Phase 2]
Phase 2 trial evaluating pleurectomy/decortication with intraoperative heated cisplatin and sodium thiosulfate for malignant pleural mesothe…
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CLINICAL_TRIALS trial_result · 2016-06-01Clinical Trial Update: Vascularity Impact on the Treatment Outcome in Malignant Pleural Mesothelioma(VITMPM)
A completed clinical trial evaluating how tumor vascularity influences treatment outcomes in malignant pleural mesothelioma.
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CLINICAL_TRIALS trial_result · 2015-10-21Clinical Trial Update: S0509 - AZD2171 in Treating Patients With Malignant Pleural Mesothelioma That Cannot Be Removed By Surgery [Phase 2]
Phase 2 clinical trial update for AZD2171 (S0509) in malignant pleural mesothelioma unsuitable for surgery; study completed with posted resu…
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CLINICAL_TRIALS trial_result · 2015-09-22Clinical Trial Update: Intrapleural Gene Transfer for Pleural Mesothelioma [Phase 1]
This document reports the completion of a Phase 1 trial evaluating intrapleural gene transfer for malignant pleural mesothelioma.
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CLINICAL_TRIALS trial_result · 2015-09-17Clinical Trial Update: A Phase II Study of Single-agent DOVitinib in Advanced Malignant PlEural Mesothelioma Which Has Progressed Following Prior Platinum-Antifolate Chemotherapy [Phase 2]
This document reports the termination of a Phase II trial of single-agent dovitinib in advanced malignant pleural mesothelioma that progress…
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CLINICAL_TRIALS research · 2015-08-06Clinical Trial Update: Response Evaluation in Malignant Pleural Mesothelioma
This update provides information on the clinical trial NCT00969098 evaluating response evaluation in malignant pleural mesothelioma.
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CLINICAL_TRIALS research · 2015-07-14Clinical Trial Update: Four Versus Six Cycles of Pemetrexed/Platinum for MPM [Phase 2]
An update on a Phase 2 trial comparing four versus six cycles of pemetrexed/platinum therapy for malignant pleural mesothelioma.
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CLINICAL_TRIALS trial_result · 2015-06-10Clinical Trial Update: Isolated Thoracic Perfusion (ITP-F) for MPM
A clinical trial evaluating Isolated Thoracic Perfusion with ITP-F for malignant pleural mesothelioma has completed.
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CLINICAL_TRIALS trial_result · 2015-04-20Clinical Trial Update: Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivity [Phase 2]
Phase 2 trial evaluating everolimus for malignant pleural mesothelioma with Merlin/NF2 loss as a biomarker; results have been posted after c…
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CLINICAL_TRIALS research · 2015-01-30Clinical Trial Update: Thromboelastography During Surgery for Malignant Pleural Mesothelioma
This entry reports on an ongoing clinical trial evaluating thromboelastography during surgery for malignant pleural mesothelioma, sponsored …
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CLINICAL_TRIALS trial_result · 2014-12-31Clinical Trial Update: Bortezomib in Treating Patients With Malignant Pleural Mesothelioma [Phase 2]
This clinical trial update reports the completion of a Phase 2 study evaluating bortezomib in patients with malignant pleural mesothelioma; …
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: Molecular Predictors of Pemetrexed and Carboplatin Response in Malignant Pleural Mesothelioma (MPM) Patients
A completed clinical trial evaluating molecular predictors of response to the chemotherapy regimen pemetrexed and carboplatin in malignant p…
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CLINICAL_TRIALS trial_result · 2014-11-20Clinical Trial Update: A Clinical Trial of ADI-PEG 20TM in Patients With Malignant Pleural Mesothelioma [Phase 2]
This document provides a status update on a Phase 2 clinical trial of ADI-PEG 20 for malignant pleural mesothelioma.
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FDA approval · 2014-08-11FDA Approved: ALIMTA — Supplemental Application (Eli Lilly and Company)
The FDA approved a supplemental application for ALIMTA (pemetrexed disodium) submitted by Eli Lilly and Company.
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CLINICAL_TRIALS trial_result · 2014-03-27Clinical Trial Update: Pleurectomy/Decortication Followed by Intrathoracic/Intraperitoneal Heated Cisplatin for Malignant Pleural Mesothelioma [Phase 1]
A Phase 1 clinical trial evaluating pleurectomy/decortication followed by intrathoracic and intraperitoneal heated cisplatin for malignant p…