Malignant Pleural Mesothelioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Dual-Target MSLN/FAP CAR-NK Cells for Pleural and Peritoneal Mesothelioma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating dual-target MSLN/FAP CAR-NK cells for malignant pleural and peritoneal mesothelioma; the study is c…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Short Neoadjuvant Hemithoracic IMRT for MPM [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating short neoadjuvant hemithoracic IMRT for malignant pleural mesothelioma.
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: From Presentation to Diagnosis: Patterns of Pleural Effusion
A completed clinical trial update from Mansoura University Hospital examining patterns of pleural effusion in malignant pleural mesothelioma…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Intrapleural Photodynamic Therapy in a Multimodal Treatment for Patients With Malignant Pleural Mesothelioma [Phase 2]
A Phase 2 clinical trial evaluating intrapleural photodynamic therapy as part of multimodal treatment for malignant pleural mesothelioma has…
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Pembrolizumab and Hypofractionated Stereotactic Radiotherapy in Patients With Malignant Pleural Mesothelioma [Phase 1]
A Phase 1 trial evaluating pembrolizumab in combination with hypofractionated stereotactic radiotherapy for advanced malignant pleural mesot…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: DuRvalumab With chEmotherapy as First Line treAtment in Advanced Pleural Mesothelioma [Phase 3]
Phase 3 trial evaluating durvalumab with chemotherapy as first-line therapy for advanced malignant pleural mesothelioma has completed.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Study of the Efficacy and Safety of the Bintrafusp Alfa in Previously Treated Advanced Malignant Pleural Mesothelioma [Phase 2]
Phase 2 trial evaluating the efficacy and safety of bintrafusp alfa in previously treated advanced malignant pleural mesothelioma has comple…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors [Phase 1, Phase 2]
Clinical trial update reports the completion of a Phase 1/2 safety and efficacy study of CTX131 in adults with relapsed or refractory solid …
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CLINICAL_TRIALS trial_result · 2025-11-13Clinical Trial Update: Pembrolizumab After Radiation Therapy in Treating Patients With Pleural Malignant Mesothelioma [Phase 1]
A Phase 1 clinical trial evaluating pembrolizumab after radiation therapy in patients with malignant pleural mesothelioma. Results were post…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: Stereotactic Body Radiation Therapy With Immunotherapy for the Treatment of Mesothelioma [Phase 1]
A Phase 1 clinical trial evaluating stereotactic body radiation therapy in combination with immunotherapy for malignant pleural mesothelioma…
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: Observational Study in Patients With Previously Unresectable Malignant Pleural Mesothelioma Treated With Nivolumab and Ipilimumab (MESO-IMMUNE)
This clinical trial update reports the completion of an observational study of nivolumab plus ipilimumab in patients with previously unresec…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Nintedanib as Switch Maintenance Treatment of Pleural Malignant Mesothelioma [Phase 2]
A Phase 2 trial of nintedanib as switch maintenance therapy for malignant pleural mesothelioma has been terminated.
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Combination Chemotherapy With or Without Surgery & Chemoradiotherapy in Patients With Malignant Pleural Mesothelioma [Phase 2]
Phase 2 clinical trial evaluating combination chemotherapy with or without surgery and chemoradiotherapy in malignant pleural mesothelioma; …
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: CART-meso in Mesothelin Expressing Cancers [Phase 1]
Phase 1 update on CART-meso, a mesothelin-targeted CAR T-cell therapy, tested in mesothelin-expressing cancers including metastatic pancreat…
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: Poly-ICLC (Hiltonol®) Vaccine In Malignant Pleural Mesothelioma [Phase 1]
Phase 1 trial of Poly-ICLC (Hiltonol) vaccine in malignant pleural mesothelioma has been completed.
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CLINICAL_TRIALS trial_result · 2025-06-18Clinical Trial Update: APG-2449 in Patients With Advanced Solid Tumors [Phase 1]
A Phase 1 trial of APG-2449 in patients with advanced solid tumors is currently recruiting, including non-small cell lung cancer, esophageal…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: BEAT-meso: Bevacizumab and Atezolizumab in Malignant Pleural Mesothelioma [Phase 3]
Phase 3 BEAT-meso trial evaluating bevacizumab and atezolizumab in malignant pleural mesothelioma has completed.
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CLINICAL_TRIALS trial_result · 2025-05-20Clinical Trial Update: Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesothelioma [Phase 3]
Phase 3 trial update reports efficacy and safety results for a combination of rAd-IFN with celecoxib and gemcitabine in malignant pleural me…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: Autologous Dendritic Cell Vaccination in Mesothelioma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating an autologous dendritic cell vaccine for malignant pleural mesothelioma has completed enrollment.
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Multicenter Single-Arm Study of Ivonescimab (AK112) Combined with Chemotherapy in Pretreated Pleural Mesothelioma [Phase 2]
Phase 2 multicenter single-arm trial evaluating Ivonescimab (AK112) plus chemotherapy for pretreatment malignant pleural mesothelioma; the s…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma [Phase 3]
A Phase 3 trial testing the addition of targeted radiation therapy to surgery and standard pemetrexed plus cisplatin or carboplatin chemothe…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: Nivolumab With Chemotherapy in Pleural Mesothelioma After Surgery [Phase 2]
A Phase 2 trial evaluating nivolumab in combination with chemotherapy after surgical resection in malignant pleural mesothelioma has complet…
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CLINICAL_TRIALS trial_result · 2025-01-20Clinical Trial Update: A Study of Yervoy and Opdivo Combination Therapy in Participants With Unresectable Advanced/Recurrent Malignant Pleural Mesothelioma (MPM)
Clinical trial evaluating the combination of Yervoy (ipilimumab) and Opdivo (nivolumab) in unresectable advanced or recurrent malignant pleu…
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Staging Procedures to Diagnose Malignant Pleural Mesothelioma
The Mayo Clinic-sponsored trial evaluating staging procedures to diagnose malignant pleural mesothelioma has been terminated.
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: Pembrolizumab in Patients With Advanced Malignant Pleural Mesothelioma [Phase 2, Phase 3]
This document reports the completion and posted results from a Phase 2/3 clinical trial evaluating pembrolizumab in patients with advanced m…