Malignant Pleural Mesothelioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-02-10Clinical Trial Update: Nivolumab Monotherapy or Nivolumab Plus Ipilimumab, for Unresectable Malignant Pleural Mesothelioma (MPM) Patients [Phase 2]
Phase 2 trial update evaluating nivolumab alone or with ipilimumab in unresectable malignant pleural mesothelioma has completed enrollment.
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CLINICAL_TRIALS trial_result · 2021-01-26Clinical Trial Update: Neoadjuvant Toripalimab Combined With Chemotherapy in the Treatment of Malignant Pleural Mesothelioma [Phase 2]
Phase 2 trial evaluating neoadjuvant toripalimab plus chemotherapy for malignant pleural mesothelioma is ongoing; status is unknown.
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CLINICAL_TRIALS trial_result · 2021-01-22Clinical Trial Update: Study of the Combination of Tivantinib Plus Pemetrexed and Carboplatin [Phase 1, Phase 2]
Clinical trial updates on the combination of tivantinib with pemetrexed and carboplatin in malignant pleural mesothelioma and nonsquamous no…
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CLINICAL_TRIALS trial_result · 2021-01-22Clinical Trial Update: Combination of Gemcitabine and Imatinib Mesylate in Pemetrexed-pretreated Patients With Pleural Mesothelioma [Phase 2]
Phase 2 trial evaluating gemcitabine combined with imatinib mesylate in pemetrexed-pretreated malignant pleural mesothelioma completed.
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Ipilimumab and Nivolumab in the Treatment of Malignant Pleural Mesothelioma [Phase 2]
Phase 2 trial update investigating ipilimumab and nivolumab for malignant pleural mesothelioma has been completed.
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CLINICAL_TRIALS trial_result · 2020-10-26Clinical Trial Update: Suberoylanilide Hydroxamic Acid (Vorinostat, MK-0683) Versus Placebo in Advanced Malignant Pleural Mesothelioma (MK-0683-014) [Phase 3]
Phase 3 trial comparing vorinostat (MK-0683) to placebo in advanced malignant pleural mesothelioma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-10-08Clinical Trial Update: A Randomised Phase II Open-label Study With a Phase Ib Safety lead-in Cohort of ONCOS-102, an Immune-priming GM-CSF Coding Oncolytic Adenovirus, and Pemetrexed/Cisplatin in Patients With Unresectable Malignant Pleural Mesothelioma [Phase 1, Phase 2]
Phase I safety lead-in followed by Phase II randomised study evaluating ONCOS-102 with pemetrexed/c cisplatin in unresectable malignant pleu…
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CLINICAL_TRIALS trial_result · 2020-09-30Clinical Trial Update: Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural Mesothelioma [Phase 1]
Phase 1 trial evaluating safety and efficacy ofListeria-based therapy combined with chemotherapy as front-line treatment for malignant pleur…
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CLINICAL_TRIALS trial_result · 2020-09-25Clinical Trial Update: Clinical Study of YS110 in Patients With Malignant Pleural Mesothelioma [Phase 1, Phase 2]
Clinical study of YS110 in malignant pleural mesothelioma has completed Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: Phase II Anetumab Ravtansine as 2nd Line Treatment for Malignant Pleural Mesothelioma (MPM) [Phase 2]
Phase II trial update for Anetumab Ravtansine as second-line treatment in malignant pleural mesothelioma has completed with results posted i…
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CLINICAL_TRIALS trial_result · 2020-07-09Clinical Trial Update: Efficacy of a Maintenance Treatment With TALAzoparib Following First Line Platinum-based Chemotherapy in Malignant MESOthelioma [Phase 2]
Phase 2 trial evaluating maintenance TALAzoparib after first-line platinum chemotherapy in advanced malignant pleural or peritoneal mesothel…
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CLINICAL_TRIALS trial_result · 2020-03-17Clinical Trial Update: Study of the Safety and Efficacy of Amatuximab in Combination With Pemetrexed and Cisplatin in Subjects With Unresectable Malignant Pleural Mesothelioma (MPM) [Phase 2]
Phase 2 study of amatuximab combined with pemetrexed and cisplatin in unresectable malignant pleural mesothelioma was terminated with result…
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CLINICAL_TRIALS trial_result · 2020-02-18Clinical Trial Update: Accelerated Hypofractionated Radiation Therapy Immediately Before Surgery in Treating Patients With Malignant Pleural Mesothelioma [NA]
Clinical trial update on accelerated hypofractionated radiation therapy before surgery for malignant pleural mesothelioma; study is terminat…
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CLINICAL_TRIALS trial_result · 2020-02-05Clinical Trial Update: Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating pemetrexed disodium with cisplatin, with or without cediranib, in malignant pleural mesothelioma; result…
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CLINICAL_TRIALS trial_result · 2020-01-23Clinical Trial Update: ATREUS - Phase II Study on the Activity of Trabectedin in Patients With Malignant Pleural Mesothelioma (MPM) [Phase 2]
Phase II study evaluating activity of trabectedin in malignant pleural mesothelioma has completed.
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CLINICAL_TRIALS trial_result · 2019-11-22Clinical Trial Update: Mesothelin-Targeted Immunotoxin LMB-100 in Combination With SEL-110 in Subjects With Malignant Pleural or Peritoneal Mesothelioma [Phase 1]
Phase 1 trial evaluating LMB-100 in combination with SEL-110 for mesothelioma has been terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-11-13Clinical Trial Update: Ganetespib With Platinum, in Patients With Malignant Pleural Mesothelioma [Phase 1, Phase 2]
Phase 1/2 trial evaluating ganetespib with platinum in malignant pleural mesothelioma has completed.
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CLINICAL_TRIALS trial_result · 2019-11-12Clinical Trial Update: A Phase 2 Study of Durvalumab in Combination With Tremelimumab in Malignant Pleural Mesothelioma [Phase 2]
Phase 2 study of durvalumab in combination with tremelimumab for malignant pleural mesothelioma was terminated, with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-09-17Clinical Trial Update: NGR015: Study in Second Line for Patient With Advanced Malignant Pleural Mesothelioma Pretreated With Pemetrexed [Phase 3]
Phase 3 trial update for NGR015 in second-line malignant pleural mesothelioma; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-05-15Clinical Trial Update: Pemetrexed Disodium and Cisplatin Followed by Surgery With or Without Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma [Phase 2]
Phase 2 clinical trial evaluating pemetrexed disodium and cisplatin followed by surgery with or without radiation therapy for malignant pleu…
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: Evaluation of CRS-207 With Pembrolizumab in Previously Treated Malignant Pleural Mesothelioma (MPM) [Phase 2]
Phase 2 trial evaluating CRS-207 with pembrolizumab in previously treated malignant pleural mesothelioma was terminated.
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CLINICAL_TRIALS trial_result · 2019-01-16Clinical Trial Update: Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Malignant Pleural Mesothelioma [Phase 2]
Phase 2 trial of NGR-hTNF as a single agent in advanced or metastatic malignant pleural mesothelioma completed.
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CLINICAL_TRIALS trial_result · 2019-01-15Clinical Trial Update: Phase II Study of NGR-hTNF Versus Placebo as Maintenance Treatment in Patients With Advanced MPM [Phase 2]
Phase II trial evaluating NGR-hTNF vs placebo as maintenance in advanced malignant pleural mesothelioma has completed.
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CLINICAL_TRIALS trial_result · 2018-09-25Clinical Trial Update: Safety and Efficacy of TTFields (150 kHz) Concomitant With Pemetrexed and Cisplatin or Carboplatin in Malignant Pleural Mesothelioma (STELLAR) [Phase 2]
Phase 2 trial evaluating TTFields (150 kHz) with pemetrexed and platinum in malignant pleural mesothelioma has completed.
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CLINICAL_TRIALS trial_result · 2018-01-29Clinical Trial Update: PIT: Prophylactic Irradiation of Tracts in Patients With Malignant Pleural Mesothelioma [Phase 3]
Phase 3 trial update for prophylactic irradiation of tracts in malignant pleural mesothelioma has been terminated.