Malignant Peripheral Nerve Sheath Tumor
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Incidence of Malignant Peripheral Nerve Sheath Tumor (MPNST) Development in Participants With Neurofibromatosis Type 1 (NF1) Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas (PN)
The NCI-sponsored clinical trial NCT04774289, now completed, compared the incidence of malignant peripheral nerve sheath tumors in people wi…
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CLINICAL_TRIALS trial_result · 2023-12-26Clinical Trial Update: SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors [Phase 2]
Phase 2 clinical trial evaluating MEK inhibitor selumetinib plus mTOR inhibitor sirolimus for malignant peripheral nerve sheath tumors (MPNS…
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma [Phase 2]
Phase 2 trial evaluating doxorubicin with upfront dexrazoxane for advanced or metastatic soft tissue sarcoma has completed enrollment with r…
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CLINICAL_TRIALS trial_result · 2019-08-29Clinical Trial Update: Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma [Phase 2]
Phase 2 trial update for Lorvotuzumab Mertansine in several relapsed/refractory pediatric solid tumors; study completed with results posted …
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CLINICAL_TRIALS trial_result · 2018-05-25Clinical Trial Update: Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors [Phase 2]
Phase 2 clinical trial evaluating combination chemotherapy for stage III/IV malignant peripheral nerve sheath tumors in patients with Neurof…
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors [Phase 1]
This update reports the completion of a Phase 1 clinical trial evaluating HSV-1716 in patients with non-CNS solid tumors, including rhabdomy…
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: S0330 Erlotinib in Treating Patients With Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumor [Phase 2]
A Phase 2 trial of erlotinib for unresectable or metastatic malignant peripheral nerve sheath tumor has completed, with results posted in 20…
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CLINICAL_TRIALS trial_result · 2016-12-28Clinical Trial Update: Alisertib in Treating Patients With Advanced or Metastatic Sarcoma [Phase 2]
A Phase 2 trial update of alisertib in patients with advanced or metastatic soft tissue sarcomas, including myxofibrosarcoma and several his…
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS) [Phase 1, Phase 2]
Phase 1/2 trial of gemcitabine and docetaxel with pazopanib for neoadjuvant treatment in soft tissue sarcoma was terminated; results posted …
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CLINICAL_TRIALS trial_result · 2015-12-04Clinical Trial Update: Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy [NA]
Completed clinical trial evaluating the effects of preoperative physical therapy in patients with lower extremity bone sarcomas; results are…
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Sorafenib and Dacarbazine in Soft Tissue Sarcoma [Phase 2]
A Phase 2 study evaluating the combination of sorafenib and dacarbazine in soft tissue sarcoma reported completed results in 2015, including…
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CLINICAL_TRIALS trial_result · 2014-01-20Clinical Trial Update: Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma [Phase 2]
Phase 2 clinical trial evaluating sorafenib for metastatic, locally advanced, or recurrent sarcoma has completed and posted results in 2014.
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CLINICAL_TRIALS research · 2013-01-28Clinical Trial Update: Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in Neurofibromatosis
This clinical trial update discusses using whole-body diffusion-weighted MRI to evaluate neurofibromatosis type 1 and its potential to detec…
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CLINICAL_TRIALS research · 2010-10-11Clinical Trial Update: Microarray CGH Analysis of Circulating Tumoral Plasma DNA in NF1 Patients With MPNSTs
A clinical trial update describing a study that analyzes circulating tumoral DNA in Neurofibromatosis Type 1 patients with malignant periphe…