Malignant Neoplasms

• CLINICAL_TRIALS research · 2026-04-13
  Clinical Trial Update: A Clinical Study of Calderasib (MK-1084) in People With Advanced Solid Tumors (MK-1084-014) [Phase 2]

  Phase 2 study of Calderasib (MK-1084) in adults with advanced malignant solid tumors is currently recruiting (NCT07209111), sponsored by Mer…

• CLINICAL_TRIALS research · 2026-04-02
  Clinical Trial Update: Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers

  This update notes ongoing recruitment for a study collecting immunology specimens from healthy volunteers and patients with various hematolo…

• CLINICAL_TRIALS trial_result · 2026-03-27
  Clinical Trial Update: Stimulation of Acupuncture Points by Athermic Laser Therapy for the Prevention of Chemotherapy Induced Nausea and Vomiting in Children [NA]

  A completed clinical trial evaluated athermic laser therapy stimulating acupuncture points to prevent chemotherapy-induced nausea and vomiti…

• EMA approval · 2026-02-19
  EMA Authorised: Fulphila (pegfilgrastim) — Biosimilar Collaborations Ireland Limited

  EMA authorised Fulphila, a pegfilgrastim biosimilar by Biosimilar Collaborations Ireland Limited. The approval covers its use to reduce the …

• CLINICAL_TRIALS trial_result · 2026-02-13
  Clinical Trial Update: A Real-World Study on the Efficacy, Safety, and Quality of Life of Different Treatment Approaches for Post-Chemotherapy Neutropenia in Cancer Patients

  This completed real-world study evaluates how different treatment strategies for post-chemotherapy neutropenia affect efficacy, safety, and …

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• CLINICAL_TRIALS trial_result · 2025-02-19
  Clinical Trial Update: Phase I/II Clinical Study of 1A46 Drug Substance [Phase 1]

  Phase I/II study of the 1A46 drug substance for advanced malignancies has been terminated.

• CLINICAL_TRIALS trial_result · 2024-08-21
  Clinical Trial Update: A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK117 as Monotherapy or in Combination With AK104 [Phase 1]

  The completed Phase 1 trial evaluated the safety, pharmacokinetics, and antitumor activity of AK117 as a standalone therapy or in combinatio…

• CLINICAL_TRIALS research · 2024-05-29
  Clinical Trial Update: Cancer Therapy-related Cardiac Dysfunction Occuring in Children Treated by Anticancer Drugs for Malignancies

  A pediatric clinical trial is assessing cancer therapy-related cardiac dysfunction in children treated with anticancer drugs for malignancie…

• CLINICAL_TRIALS trial_result · 2023-12-12
  Clinical Trial Update: Apixaban in Preventing Secondary Cancer Related Venous Thrombosis in Cancer Patients Who Have Completed Anticoagulation Therapy [Phase 3]

  A Phase 3 trial evaluated apixaban to prevent recurrent cancer-related venous thromboembolism in patients who completed initial anticoagulat…

• CLINICAL_TRIALS trial_result · 2023-09-21
  Clinical Trial Update: Oxygen Measurements in Subcutaneous Tumors by EPR Oximetry Using OxyChip [NA]

  Clinical trial update for an imaging study using OxyChip to measure oxygen in subcutaneous tumors; the study is terminated with results post…

• CLINICAL_TRIALS trial_result · 2023-03-24
  Clinical Trial Update: A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer [Phase 1, Phase 2]

  A phase 1/2 trial evaluating bempegaldesleukin (BEMPEG) in combination with nivolumab in pediatric and young adult patients with recurrent o…

• CLINICAL_TRIALS trial_result · 2017-02-07
  Clinical Trial Update: Extended Infusion Carfilzomib on a Weekly Schedule in Patients With Advanced Solid Tumors [Phase 1]

  A Phase 1 study evaluating extended weekly infusions of carfilzomib in patients with advanced solid tumors has been completed.

• CLINICAL_TRIALS trial_result · 2016-02-17
  Clinical Trial Update: Phase I, Dose Escalation of SAR125844 in Asian Solid Tumor Patients [Phase 1]

  Phase I dose-escalation study of SAR125844 in Asian patients with solid tumors has been completed.

• CLINICAL_TRIALS trial_result · 2015-08-27
  Clinical Trial Update: Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED) [Phase 1]

  Phase 1 safety study of AP23573 (deforolimus) in patients with advanced, refractory, or recurrent malignancies has completed, including lymp…

• CLINICAL_TRIALS trial_result · 2014-12-03
  Clinical Trial Update: Dose-escalation, Safety, Pharmacokinetics Study of AVE8062 Combined With Bevacizumab in Patients With Advanced Solid Tumors [Phase 1]

  Phase 1 dose-escalation study assessing safety, dosing, and pharmacokinetics of AVE8062 in combination with bevacizumab in adults with advan…

• CLINICAL_TRIALS trial_result · 2013-10-16
  Clinical Trial Update: Dose Escalation, Safety and Pharmacokinetic Study of AVE8062 Combined With Docetaxel and Cisplatin in Patients With Solid Tumors [Phase 1]

  Phase 1 dose-escalation study evaluating safety and pharmacokinetics of AVE8062 combined with docetaxel and cisplatin in patients with solid…

• CLINICAL_TRIALS trial_result · 2013-09-11
  Clinical Trial Update: Dose-Escalation, Safety, Pharmacokinetics Study of Cabazitaxel With Gemcitabine In Patients With Solid Tumor [Phase 1, Phase 2]

  A phase 1/2 dose-escalation study evaluating the safety, pharmacokinetics, and dose-finding of cabazitaxel in combination with gemcitabine i…

• CLINICAL_TRIALS trial_result · 2011-12-16
  Clinical Trial Update: Effect of Cabazitaxel on the QTc Interval in Cancer Patients [Phase 1]

  A Phase 1 trial evaluated the effect of cabazitaxel on the QTc interval in patients with malignant neoplasms; the study has completed.

• CLINICAL_TRIALS trial_result · 2011-06-13
  Clinical Trial Update: Dose Escalation, Safety and Pharmacokinetic Study of AVE8062 Combined With Cisplatin in Patients With Solid Tumors [Phase 1]

  Phase 1 dose-escalation study evaluating safety, pharmacokinetics, and tolerability of AVE8062 in combination with cisplatin in patients wit…

• CLINICAL_TRIALS trial_result · 2010-11-25
  Clinical Trial Update: A Safety Study Of Sunitinib In Combination With Pemetrexed In Patients With Advanced Solid Malignancies [Phase 1]

  This Phase 1 safety study evaluates the combination of sunitinib and pemetrexed in patients with advanced solid malignancies to assess safet…

• CLINICAL_TRIALS trial_result · 2010-04-26
  Clinical Trial Update: A Safety and Dose-finding Study of JNJ-26483327, a Drug in Development for Cancer, for Patients With Advanced and/or Refractory Solid Malignancies. [Phase 1]

  Phase 1 safety and dose-finding study of JNJ-26483327 in patients with advanced solid malignancies has been completed.