Malignant Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-12-17Clinical Trial Update: A Study of the Effect of Food on the Pharmacokinetics of Single Dose RO5185426 And the Safety And Efficacy of Continuous Administration in Patients With BRAF V600E Mutation-Positive Metastatic Melanoma [Phase 1]
The trial investigated how food affects the pharmacokinetics of a single dose of RO5185426 and evaluated the safety and efficacy of continuo…
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CLINICAL_TRIALS trial_result · 2015-12-08Clinical Trial Update: A Pharmacokinetic and Metabolism Study of 14C-labeled RO5185426 on Patients With Metastatic Melanoma [Phase 1]
Phase 1 pharmacokinetic and metabolism study of radiolabeled RO5185426 in patients with metastatic melanoma; study completed with results po…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Improving Sun-Protective Behaviors and Skin Self-Examinations Among African Americans [NA]
This clinical trial update reports completion of a study aimed at improving sun-protective behaviors and skin self-examinations among Africa…
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CLINICAL_TRIALS trial_result · 2015-10-30Clinical Trial Update: A Study Comparing Vemurafenib Versus Vemurafenib Plus Cobimetinib in Participants With Metastatic Melanoma [Phase 3]
A Phase 3 trial comparing vemurafenib alone versus vemurafenib with cobimetinib in metastatic melanoma has completed with posted results.
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CLINICAL_TRIALS trial_result · 2015-08-26Clinical Trial Update: A Pharmacokinetic/Pharmacodynamic Study of RO5185426 in Previously Treated Patients With Metastatic Melanoma [Phase 1]
Phase 1 pharmacokinetic/pharmacodynamic study of RO5185426 in patients with previously treated metastatic melanoma; results have been posted…
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Transfected Dendritic Cell Based Therapy for Patients With Breast Cancer or Malignant Melanoma [Phase 1]
Phase 1 study of transfected dendritic cell–based therapy in patients with breast cancer or malignant melanoma has completed.
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CLINICAL_TRIALS trial_result · 2015-07-21Clinical Trial Update: A Phase II Study to Evaluate Safety and Efficacy of Combined Treatment With Ipilimumab and Intratumoral Interleukin-2 [Phase 2]
This update reports results from a Phase II study evaluating the safety and efficacy of combining ipilimumab with intratumoral interleukin-2…
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Activated Allogeneic Lymphocytes for Induction Graft Versus Tumor Effect in Metastatic Solid Tumors [Phase 2]
Phase 2 study evaluating activated allogeneic lymphocytes to induce a graft-versus-tumor effect in metastatic solid tumors, including metast…
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CLINICAL_TRIALS trial_result · 2015-05-27Clinical Trial Update: Intratumoral Administration of L19IL2/L19TNF [Phase 2]
A Phase 2 trial evaluating intratumoral L19IL2/L19TNF in malignant melanoma (skin) has been completed.
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: A Combination of Ipilimumab and Fotemustine for Treat Unresectable Locally Advanced or Metastatic Melanoma [Phase 2]
A Phase 2 clinical trial evaluating the combination of ipilimumab and fotemustine for unresectable locally advanced or metastatic melanoma h…
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FDA approval · 2015-05-06FDA Approved: PROLEUKIN — Supplemental Application (Iovance Biotherapeutics, Inc)
The FDA approved a supplemental application for PROLEUKIN (aldesleukin) filed by Iovance Biotherapeutics, Inc, indicating an updated regulat…
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CLINICAL_TRIALS trial_result · 2015-03-19Clinical Trial Update: Lapatinib in Stage IV Melanoma With ERBB4 Mutations [Phase 2]
Phase 2 trial of lapatinib in stage IV melanoma with ERBB4 mutations was terminated; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: A Study of Pegylated Interferon Alfa-2b (MK-4031) as an Adjuvant Treatment in Japanese Patients With Malignant Melanoma (MK-4031-370) [Phase 1]
Phase 1 study of pegylated interferon alfa-2b (MK-4031) as adjuvant treatment in Japanese patients with malignant melanoma was terminated; r…
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CLINICAL_TRIALS trial_result · 2014-12-30Clinical Trial Update: Study of Patients With Stage IV Malignant Melanoma Using PS-341 (Bortezomib, Velcade) and Interferon-alpha-2b in Malignant Melanoma [Phase 1]
Phase 1 clinical trial evaluating safety and feasibility of combining bortezomib (PS-341) with interferon-alpha-2b in patients with malignan…
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FDA approval · 2014-11-25FDA Approved: ZELBORAF — Supplemental Application (Genentech, Inc.)
FDA approved a supplemental application for Zelboraf (vemurafenib) submitted by Genentech, Inc., representing an additional regulatory actio…
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CLINICAL_TRIALS trial_result · 2014-11-13Clinical Trial Update: NAM-Trial: Multiferon in Malignant Melanoma [Phase 2]
A Phase 2 clinical trial update for Multiferon in malignant melanoma with locoregional metastases (stages IIIB/C) has completed.
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CLINICAL_TRIALS trial_result · 2014-11-05Clinical Trial Update: Trial With Telomerase Peptide Vaccine In Combination With Temozolomide in Patients With Advanced Malignant Melanoma [Phase 1, Phase 2]
This document reports an update on a Phase 1/2 trial evaluating a telomerase peptide vaccine in combination with temozolomide for advanced m…
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CLINICAL_TRIALS trial_result · 2014-09-26Clinical Trial Update: Vaccination With Peptides in Combination With Either Ipilimumab or Vemurafenib for the Treatment of Unresectable Stage III or IV Malignant Melanoma [Phase 1]
Phase 1 study evaluating peptide vaccination in combination with ipilimumab or vemurafenib for unresectable stage III or IV malignant melano…
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CLINICAL_TRIALS trial_result · 2014-09-05Clinical Trial Update: Phase II Trial of Ontak With Metastatic Melanoma [Phase 2]
Phase II trial evaluating Ontak (denileukin diftitox) in metastatic melanoma has completed, with results posted in 2014. The update summariz…
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CLINICAL_TRIALS trial_result · 2014-08-29Clinical Trial Update: A Study to Evaluate the Efficacy of Docetaxel and Carboplatin in Metastatic Malignant Melanoma Failed First-Line Dacabazine or Temozolomide Contained Therapy [Phase 2]
A Phase 2 clinical trial evaluating the efficacy of a docetaxel and carboplatin combination in metastatic malignant melanoma patients who fa…
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CLINICAL_TRIALS trial_result · 2014-06-25Clinical Trial Update: A Study of Avastin (Bevacizumab) in Combination With Fotemustine in Patients With Metastatic Melanoma [Phase 2]
Phase 2 trial evaluating Avastin (bevacizumab) in combination with fotemustine for metastatic melanoma completed with results posted in 2014…
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CLINICAL_TRIALS trial_result · 2014-06-18Clinical Trial Update: A Study of IMC-1121B (Ramucirumab) With or Without Dacarbazine in Metastatic Malignant Melanoma [Phase 2]
Phase 2 trial evaluating ramucirumab (IMC-1121B) with or without dacarbazine in metastatic malignant melanoma has completed and posted its r…
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CLINICAL_TRIALS trial_result · 2014-06-05Clinical Trial Update: A Trial of ABI-007 Versus Dacarbazine in Previously Untreated Patients With Metastatic Malignant Melanoma [Phase 3]
Phase 3 trial comparing ABI-007 to dacarbazine in previously untreated metastatic malignant melanoma completed with posted results.
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CLINICAL_TRIALS trial_result · 2014-05-21Clinical Trial Update: Continuation Booster Trial After a Vaccine Combining Tyrosinase/GP100/MART-1 Peptides Emulsified With Montanide ISA 51 With or Without GM-CSF for Patients With Melanoma [Phase 2]
A Phase 2 continuation booster trial using a peptide vaccine targeting melanoma antigens (tyrosinase, GP100, MART-1) emulsified with Montani…
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CLINICAL_TRIALS trial_result · 2014-01-08Clinical Trial Update: Abraxane and Avastin as Therapy for Patients With Malignant Melanoma, a Phase II Study [Phase 2]
A Phase II study evaluated Abraxane in combination with Avastin in patients with metastatic malignant melanoma, with results posted after tr…