Malignant Melanoma
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CLINICAL_TRIALS trial_result · 2012-10-16Clinical Trial Update: Immunohistochemical Expression Patterns of microRNA Processing Enzyme Dicer in Cutaneous Malignant Melanoma, Benign and Dysplastic Melanocytic Naevi
Completed study evaluating immunohistochemical expression of Dicer, a microRNA processing enzyme, in cutaneous malignant melanoma and benign…
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CLINICAL_TRIALS trial_result · 2012-09-07Clinical Trial Update: Study of Heat Shock Protein-Peptide Complex (HSPPC-96) Versus IL-2/DTIC for Stage IV Melanoma [Phase 3]
A Phase 3 trial comparing Heat Shock Protein-Peptide Complex-96 (HSPPC-96) to IL-2 plus dacarbazine in Stage IV malignant melanoma has compl…
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CLINICAL_TRIALS trial_result · 2012-07-10Clinical Trial Update: Sorafenib With Either Temsirolimus or Tipifarnib in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed By Surgery [Phase 2]
Phase 2 clinical trial evaluating sorafenib in combination with temsirolimus or tipifarnib in patients with stage IV malignant melanoma that…
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CLINICAL_TRIALS trial_result · 2012-06-06Clinical Trial Update: CP-675,206 In Patients With Advanced Melanoma [Phase 2]
A Phase 2 trial evaluating CP-675,206 in patients with advanced malignant melanoma has completed. The trial was sponsored by AstraZeneca.
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CLINICAL_TRIALS trial_result · 2012-05-03Clinical Trial Update: A Phase II Trial OF Carboplatin, ABI-007 (Abraxane) And Sorafenib (BAY 43-9006) in Metastatic Melanoma [Phase 2]
A Phase II trial evaluating carboplatin, Abraxane (paclitaxel protein-bound particles), and sorafenib in metastatic melanoma has completed.
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CLINICAL_TRIALS trial_result · 2012-05-03Clinical Trial Update: Phase II Trial of (IL-2) With Priming and (GM-CSF) in Patients With Advanced Melanoma [Phase 2]
Phase II trial evaluating interleukin-2 with priming and GM-CSF in advanced malignant melanoma has completed.
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CLINICAL_TRIALS trial_result · 2012-04-04Clinical Trial Update: Radiation Therapy and Concurrent Cisplatin Chemotherapy for Locally Advanced or Metastatic Malignant Melanoma [Phase 2]
A Phase 2 study evaluating radiation therapy with concurrent cisplatin chemotherapy for locally advanced or metastatic malignant melanoma wa…
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CLINICAL_TRIALS trial_result · 2012-03-14Clinical Trial Update: Study of the Tumor Saturation and Biological Activity of MEDI-522 (Abergrin) in Patients With Advanced Malignant Melanoma [Phase 1]
Phase 1 clinical trial update for MEDI-522 (Abergrin) in patients with advanced malignant melanoma; study completed.
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CLINICAL_TRIALS trial_result · 2012-01-05Clinical Trial Update: Pharmacokinetic Study of Liposomal Vincristine in Patients With Malignant Melanoma & Hepatic Dysfunction [Phase 1]
Phase 1 pharmacokinetic study of liposomal vincristine in patients with malignant melanoma and hepatic dysfunction has completed; results po…
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CLINICAL_TRIALS trial_result · 2011-08-11Clinical Trial Update: Post-Operative Drainage Following Lymph Node Dissection [Phase 4]
A Phase 4 clinical trial evaluated post-operative drainage following lymph node dissection in patients with malignant melanoma and squamous …
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CLINICAL_TRIALS trial_result · 2011-03-24Clinical Trial Update: Efficacy and Safety of High-dose Interferon Alfa-2b (Intron A®) for the Adjuvant Treatment of Malignant Melanoma (Study P04083)
This trial update reports results from Study P04083 evaluating high-dose interferon alfa-2b (Intron A) as adjuvant therapy for malignant mel…
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CLINICAL_TRIALS trial_result · 2010-11-15Clinical Trial Update: Safety and Immunogenicity of CYT004-MelQbG10 Vaccine With and Without Adjuvant in Advanced Stage Melanoma Patients [Phase 2]
Phase 2 clinical trial update evaluating the safety and immunogenicity of CYT004-MelQbG10 vaccine with and without adjuvant in advanced mali…
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CLINICAL_TRIALS trial_result · 2010-09-15Clinical Trial Update: Safety and Efficacy Trial of Imexon Plus DTIC in Advanced Malignant Melanoma [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating Imexon in combination with dacarbazine (DTIC) for advanced malignant melanoma, focusing on s…
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CLINICAL_TRIALS trial_result · 2010-04-26Clinical Trial Update: Study of MDX-010 in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma [Phase 1]
This update reports the completion of a Phase 1 study of MDX-010 in patients with unresectable stage III or stage IV malignant melanoma.
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CLINICAL_TRIALS trial_result · 2009-08-25Clinical Trial Update: Study of AS1409 in Patients With Either Metastatic Renal Cell Carcinoma or Metastatic Malignant Melanoma [Phase 1]
This document reports the completion of a Phase 1 study evaluating AS1409 in patients with metastatic renal cell carcinoma or metastatic mal…
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CLINICAL_TRIALS trial_result · 2009-06-02Clinical Trial Update: Thymosin Alpha 1, Interferon Alpha, or Both, in Combination With Dacarbazine in Patients With Malignant Melanoma [Phase 2]
Phase 2 trial evaluating thymosin alpha-1 and/or interferon alpha in combination with dacarbazine for malignant melanoma; results were poste…
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CLINICAL_TRIALS trial_result · 2009-03-09Clinical Trial Update: Study of Interleukin-21 for Metastatic Malignant Melanoma and Metastatic Kidney Cancer [Phase 1]
Phase 1 study evaluating Interleukin-21 for metastatic malignant melanoma and metastatic kidney cancer has completed.
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CLINICAL_TRIALS trial_result · 2009-02-05Clinical Trial Update: Temodar and Sutent as Therapy for Melanoma [Phase 1, Phase 2]
A phase 1/2 trial evaluating temozolomide (Temodar) and sunitinib (Sutent) for metastatic malignant melanoma; the study status is terminated…
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CLINICAL_TRIALS trial_result · 2007-09-20Clinical Trial Update: Safety and Immunogenicity of a Melan-A VLP Vaccine in Early Stage Melanoma Patients [Phase 1, Phase 2]
Phase 1/2 trial evaluating the safety and immunogenicity of a Melan-A virus-like particle (VLP) vaccine in patients with early-stage maligna…
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CLINICAL_TRIALS trial_result · 2007-07-10Clinical Trial Update: Clinical Study of Previously Untreated Patients With Malignant Melanoma [Phase 2]
Phase 2 clinical trial evaluating treatment in previously untreated malignant melanoma patients has completed.
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CLINICAL_TRIALS trial_result · 2007-04-19Clinical Trial Update: Intradermal Vaccination With Stabilized Tumor mRNA - a Clinical Phase I/II Trial in Melanoma Patients [Phase 1, Phase 2]
Update on a completed Phase 1/2 trial evaluating an intradermal stabilized tumor mRNA vaccine in patients with malignant melanoma.
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CLINICAL_TRIALS trial_result · 2006-09-19Clinical Trial Update: Safety and Immunogenicity of a Melan-A VLP Vaccine in Advanced Stage Melanoma Patients [Phase 2]
Phase 2 trial evaluating safety and immunogenicity of a Melan-A virus-like particle vaccine in patients with advanced malignant melanoma; th…
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CLINICAL_TRIALS trial_result · 2006-07-28Clinical Trial Update: Survivin Peptide Vaccination for Patients With Advanced Melanoma, Pancreatic, Colon and Cervical Cancer [Phase 1, Phase 2]
An early-phase trial investigating a survivin peptide vaccine in patients with advanced melanoma, pancreatic cancer, colon cancer, and cervi…
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CLINICAL_TRIALS trial_result · 2006-07-11Clinical Trial Update: GM-CSF as Adjuvant Therapy of Melanoma [Phase 2]
Phase 2 trial evaluating GM-CSF as adjuvant therapy for malignant melanoma has completed.