Malignant Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-27Clinical Trial Results: A Study of Recombinant Vaccinia Virus to Treat Malignant Melanoma [Phase 1, Phase 2]
A multicenter Phase 1/2 study evaluating recombinant vaccinia virus therapy for malignant melanoma has completed with posted results.
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CLINICAL_TRIALS trial_result · 2026-06-18Clinical Trial Results: GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2 [Phase 1]
Phase 1 trial of GD2-SADA:177Lu-DOTA complex for GD2-expressing solid tumors was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: Rigosertib Plus Pembrolizumab in Treating Patients With Unresectable/Metastatic Melanoma Refractory to PD-1 Inhibitors [Phase 2]
Phase 2 trial evaluating rigosertib in combination with pembrolizumab for unresectable or metastatic melanoma that is refractory to PD-1 inh…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: A Clinical Trial of PF-08046037 Alone or With Sasanlimab in Patients With Advanced or Metastatic Malignancies [Phase 1]
Pfizer's Phase 1 trial of PF-08046037 alone or with sasanlimab in advanced cancers has been terminated.
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: A Phase 1 of CTX-8371 in Patients With Advanced Malignancies [Phase 1]
Phase 1 clinical trial evaluating CTX-8371 in patients with advanced malignancies, including Non-Small Cell Lung Cancer and Triple-Negative …
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)
A completed Travera Inc trial evaluating TraveraRTGx and a tumor-cell biomarker intended to guide rapid therapy decisions across multiple ca…
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CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: Retinal Structural and Functional Changes in Patients Treated With BRAF/MEK Inhibitors [NA]
Completed clinical trial update describing retinal structural and functional changes in patients treated with BRAF/MEK inhibitors. The repor…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors [Phase 2]
A Phase 2 study evaluating vobramitamab duocarmazine in metastatic castration-resistant prostate cancer and other solid tumors was terminate…
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: A Study of SAR444245 Combined With Cemiplimab for the Treatment of Participants With Various Advanced Skin Cancers (Pegathor Skin 201) [Phase 1, Phase 2]
A phase 1/2 study evaluating SAR444245 in combination with cemiplimab for advanced skin cancers (malignant melanoma and squamous cell carcin…
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement [Phase 1]
A first-in-human Phase 1 trial of PF-07284890 in patients with BRAF V600 mutant solid tumors, including those with brain involvement, has be…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Study of IK-595 in RAS- or RAF-altered Advanced Tumors [Phase 1]
Phase 1 study of IK-595 in Ras- or Raf-altered advanced tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
An update on IMM-1-104's Phase 1/2a trial in advanced or metastatic solid tumors shows the study is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: Trial of TRX518 (Anti-GITR mAb) in Stage III or IV Malignant Melanoma or Other Solid Tumors [Phase 1]
A Phase 1 trial of TRX518, an anti-GITR monoclonal antibody, in unresectable stage III/IV malignant melanoma or other solid tumors has compl…
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: ImmPACT Expanded Multiple Antigen Specific Endogenously Derived T Cells (MASE-T) to Patients With Metastatic Melanoma [Phase 1]
Phase 1 study evaluating MASE-T (ImmPACT Expanded Multiple Antigen Specific Endogenously Derived T Cells) for metastatic melanoma has been t…
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: Study of Taxoprexin Injection vs. Dacarbazine in Patients With Metastatic Malignant Melanoma [Phase 3]
A Phase 3 trial comparing Taxoprexin Injection to Dacarbazine for metastatic malignant melanoma has been terminated.
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CLINICAL_TRIALS trial_result · 2025-05-28Clinical Trial Update: A Study of IMM-6-415 in RAS/RAF Mutant Solid Tumors [Phase 1, Phase 2]
This clinical trial update reports the completion of a Phase 1/2 study of IMM-6-415 in Ras/RAF-mutant solid tumors, including pancreatic ade…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Evaluating the Efficacy and Safety of a Sequencing Schedule of Cobimetinib Plus Vemurafenib Followed by Immunotherapy With an Anti- PD-L1 Antibody in Patients With Unresectable or Metastatic BRAF V600 Mutant Melanoma [Phase 2]
Phase 2 trial evaluating sequencing of cobimetinib plus vemurafenib followed by anti-PD-L1 immunotherapy in unresectable or metastatic BRAF …
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Immunotherapy With Nivolumab or Nivolumab Plus Ipilimumab vs. Double Placebo for Stage IV Melanoma w. NED [Phase 2]
A Phase 2 trial evaluating nivolumab alone or in combination with ipilimumab versus placebo in stage IV malignant melanoma has completed.
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Study of the Effects of Pembrolizumab in Patients With Advanced Solid Tumors [Phase 2]
Phase 2 study evaluating pembrolizumab in patients with advanced solid tumors, including squamous cell carcinoma of the head and neck, tripl…
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: Diagnostic Precision of the AI Tool Dermalyzer to Identify Malignant Melanomas in Subjects Seeking Primary Care for Melanoma-suspected Cutaneous Lesions
The trial evaluated the diagnostic precision of the Dermalyzer AI tool for identifying malignant melanoma in primary care patients with mela…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Safety of UV1 Vaccination in Combination With Ipilimumab in Patients With Unresectable or Metastatic Malignant Melanoma [Phase 1, Phase 2]
A completed Phase 1/2 trial assessing the safety of combining UV1 vaccination with ipilimumab in patients with unresectable or metastatic ma…
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2 [Phase 1]
Phase 1 clinical trial evaluating the GD2-SADA:177Lu-DOTA complex in GD2-expressing solid tumors is currently recruiting, including small ce…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Neoadjuvant L19IL2/L19TNF- Pivotal Study [Phase 3]
Phase 3 pivotal neoadjuvant trial of L19IL2/L19TNF for malignant melanoma is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Phase I/II Trial Investigating LOAd703 in Combination With Atezolizumab in Malignant Melanoma [Phase 1, Phase 2]
A Phase I/II study evaluating LOAd703 in combination with atezolizumab for malignant melanoma has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: UV1 Vaccine With Pembrolizumab for Patients With Unresectable or Metastatic Melanoma [Phase 1]
This clinical trial update notes the completion of a Phase 1 study evaluating UV1 vaccine in combination with pembrolizumab for unresectable…