Malignant Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of the Effect of Vemurafenib on the Pharmacokinetics of Phenprocoumon in Patients With BRAFV600 Mutation-Positive Metastatic Malignancy [Phase 1]
A completed Phase 1 trial evaluating the effect of vemurafenib on the pharmacokinetics of phenprocoumon in patients with BRAFV600 mutation-p…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of the Effect of Vemurafenib on the Pharmacokinetics of Acenocoumarol in Patients With BRAFV600 Mutation-Positive Metastatic Malignancy [Phase 1]
This Phase 1 trial evaluated the pharmacokinetic interaction between vemurafenib and acenocoumarol in BRAFV600 mutation-positive metastatic …
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CLINICAL_TRIALS trial_result · 2016-09-29Clinical Trial Update: Phase II Study to Determine Predictive Markers of Response to BMS-734016 (MDX-010) [Phase 1, Phase 2]
Clinical trial update on Phase I/II study of ipilimumab (MDX-010) in unresectable stage III or IV malignant melanoma, focusing on predictive…
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CLINICAL_TRIALS trial_result · 2016-09-28Clinical Trial Update: A Study of MDX-010 (BMS-734016) Administered With or Without Prophylactic Oral Budesonide [Phase 2]
A Phase 2 study evaluating the CTLA-4 antibody MDX-010 (BMS-734016) with or without prophylactic oral budesonide in patients with malignant …
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CLINICAL_TRIALS trial_result · 2016-08-15Clinical Trial Update: Trial of Vaccine Therapy With mRNA- Transfected Dendritic Cells in Patients With Advanced Malignant Melanoma [Phase 1, Phase 2]
An early-stage study evaluated an mRNA-transfected dendritic cell vaccine in patients with advanced malignant melanoma. The Phase 1/2 trial …
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CLINICAL_TRIALS trial_result · 2016-06-17Clinical Trial Update: A Study of Vemurafenib and GDC-0973 (Cobimetinib) in Participants With BRAFV600E Mutation-Positive Metastatic Melanoma [Phase 1]
Phase 1 study evaluating vemurafenib with cobimetinib (GDC-0973) in BRAFV600E mutation-positive metastatic melanoma completed with posted re…
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CLINICAL_TRIALS trial_result · 2016-06-09Clinical Trial Update: Study of Radiotherapy Administered in Combination With Ipilimumab in Patients With Unresectable Stage III or Stage IV Advanced Malignant Melanoma [Phase 1]
A Phase 1 study evaluating radiotherapy in combination with ipilimumab for unresectable stage III or stage IV malignant melanoma has been te…
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CLINICAL_TRIALS trial_result · 2016-06-08Clinical Trial Update: An Expanded Cohort Trial of Bortezomib and Sorafenib in Advanced Malignant Melanoma [Phase 1]
Phase 1 trial update evaluating the combination of bortezomib and sorafenib in advanced malignant melanoma has completed.
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CLINICAL_TRIALS trial_result · 2016-06-08Clinical Trial Update: A Study of Vemurafenib (Zelboraf) in Chinese Participants With BRAF V600 Mutation-Positive Unresectable or Metastatic Melanoma [Phase 1]
A Phase 1 trial update of vemurafenib in Chinese participants with BRAF V600 mutation-positive unresectable or metastatic melanoma has compl…
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CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: FR901228 in Treating Patients With Unresectable Stage III or Stage IV Malignant Melanoma [Phase 2]
Phase 2 clinical trial update for FR901228 in unresectable stage III or stage IV malignant melanoma (melanoma) has been terminated with resu…
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Phase I/IIa AdCD40L Immunogene Therapy for Malignant Melanoma and Other Solid Tumors [Phase 1, Phase 2]
This clinical trial update summarizes the completed Phase I/IIa study of AdCD40L immunogene therapy for malignant melanoma (and other solid …
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CLINICAL_TRIALS trial_result · 2016-02-11Clinical Trial Update: A Study of RO5185426 in Patients With Metastatic Melanoma [Phase 2]
Phase 2 study of RO5185426 in metastatic melanoma has completed, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-02-08Clinical Trial Update: Study of Nivolumab (BMS-936558) Plus Ipilimumab Compared With Ipilimumab Alone in the Treatment of Previously Untreated, Unresectable, or Metastatic Melanoma [Phase 2]
Phase 2 trial comparing nivolumab plus ipilimumab versus ipilimumab alone in previously untreated unresectable or metastatic melanoma has co…
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CLINICAL_TRIALS trial_result · 2015-12-17Clinical Trial Update: A Study of the Effect of Food on the Pharmacokinetics of Single Dose RO5185426 And the Safety And Efficacy of Continuous Administration in Patients With BRAF V600E Mutation-Positive Metastatic Melanoma [Phase 1]
The trial investigated how food affects the pharmacokinetics of a single dose of RO5185426 and evaluated the safety and efficacy of continuo…
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CLINICAL_TRIALS trial_result · 2015-12-08Clinical Trial Update: A Pharmacokinetic and Metabolism Study of 14C-labeled RO5185426 on Patients With Metastatic Melanoma [Phase 1]
Phase 1 pharmacokinetic and metabolism study of radiolabeled RO5185426 in patients with metastatic melanoma; study completed with results po…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Improving Sun-Protective Behaviors and Skin Self-Examinations Among African Americans [NA]
This clinical trial update reports completion of a study aimed at improving sun-protective behaviors and skin self-examinations among Africa…
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CLINICAL_TRIALS trial_result · 2015-10-30Clinical Trial Update: A Study Comparing Vemurafenib Versus Vemurafenib Plus Cobimetinib in Participants With Metastatic Melanoma [Phase 3]
A Phase 3 trial comparing vemurafenib alone versus vemurafenib with cobimetinib in metastatic melanoma has completed with posted results.
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CLINICAL_TRIALS trial_result · 2015-08-26Clinical Trial Update: A Pharmacokinetic/Pharmacodynamic Study of RO5185426 in Previously Treated Patients With Metastatic Melanoma [Phase 1]
Phase 1 pharmacokinetic/pharmacodynamic study of RO5185426 in patients with previously treated metastatic melanoma; results have been posted…
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Transfected Dendritic Cell Based Therapy for Patients With Breast Cancer or Malignant Melanoma [Phase 1]
Phase 1 study of transfected dendritic cell–based therapy in patients with breast cancer or malignant melanoma has completed.
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CLINICAL_TRIALS trial_result · 2015-07-21Clinical Trial Update: A Phase II Study to Evaluate Safety and Efficacy of Combined Treatment With Ipilimumab and Intratumoral Interleukin-2 [Phase 2]
This update reports results from a Phase II study evaluating the safety and efficacy of combining ipilimumab with intratumoral interleukin-2…
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Activated Allogeneic Lymphocytes for Induction Graft Versus Tumor Effect in Metastatic Solid Tumors [Phase 2]
Phase 2 study evaluating activated allogeneic lymphocytes to induce a graft-versus-tumor effect in metastatic solid tumors, including metast…
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CLINICAL_TRIALS trial_result · 2015-05-27Clinical Trial Update: Intratumoral Administration of L19IL2/L19TNF [Phase 2]
A Phase 2 trial evaluating intratumoral L19IL2/L19TNF in malignant melanoma (skin) has been completed.
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: A Combination of Ipilimumab and Fotemustine for Treat Unresectable Locally Advanced or Metastatic Melanoma [Phase 2]
A Phase 2 clinical trial evaluating the combination of ipilimumab and fotemustine for unresectable locally advanced or metastatic melanoma h…
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CLINICAL_TRIALS trial_result · 2015-03-19Clinical Trial Update: Lapatinib in Stage IV Melanoma With ERBB4 Mutations [Phase 2]
Phase 2 trial of lapatinib in stage IV melanoma with ERBB4 mutations was terminated; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: A Study of Pegylated Interferon Alfa-2b (MK-4031) as an Adjuvant Treatment in Japanese Patients With Malignant Melanoma (MK-4031-370) [Phase 1]
Phase 1 study of pegylated interferon alfa-2b (MK-4031) as adjuvant treatment in Japanese patients with malignant melanoma was terminated; r…