Malignant Ascites
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)
A completed Travera Inc trial evaluating TraveraRTGx and a tumor-cell biomarker intended to guide rapid therapy decisions across multiple ca…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: PMCF Study of the CE-marked Drainova® ArgentiC Catheter
This PMCF study of the CE-marked Drainova ArgentiC Catheter by ewimed GmbH has completed. It evaluated its use for pleural effusion (includi…
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: A Study of M701 (EpCAM and CD3) in Malignant Ascites [Phase 1]
A Phase 1 study of M701, an EpCAM-CD3 bispecific T-cell engager, in malignant ascites has completed; sponsor is Wuhan YZY Biopharma Co., Ltd…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: A Study on the Safety and Preliminary Efficacy of NK042 in the Treatment of Malignant Ascites [Phase 1]
A Phase 1 clinical trial update evaluating NK042 for malignant ascites in gynecologic cancer reports safety findings and preliminary efficac…
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CLINICAL_TRIALS trial_result · 2023-01-31Clinical Trial Update: Intraperitoneal Injection of Oncolytic Viruses H101 for Patients With Refractory Malignant Ascites [Phase 2]
Phase 2 clinical trial update evaluating intraperitoneal injection of oncolytic virus H101 for refractory malignant ascites has completed.
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CLINICAL_TRIALS trial_result · 2018-11-08Clinical Trial Update: A Study of Syngenon (BSG-001) for Inhalation in Subjects With Malignant Pleural Effusion and/or Malignant Ascites [Phase 1, Phase 2]
A clinical trial update for Syngenon (BSG-001) in inhalation therapy for malignant pleural effusion and malignant ascites across Phase 1 and…
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CLINICAL_TRIALS trial_result · 2018-04-09Clinical Trial Update: Retrospective Study in the Use of the Alfapump and the Treatment of Malignant Ascites
A retrospective analysis assessed the use of the Alfapump for treating malignant ascites, summarizing outcomes and safety from the completed…
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Mitomycin as a Hyperthermic Peritoneal Perfusion in Treating Patients With Malignant Ascites [Phase 2]
Phase 2 trial of mitomycin delivered via hyperthermic peritoneal perfusion for malignant ascites due to metastatic cancer, terminated.
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CLINICAL_TRIALS trial_result · 2017-08-30Clinical Trial Update: A Tolerance Trial of Cinobufacini Injection Intraperitoneal Perfusion on Digestive System Cancer With Ascites [Phase 1]
Phase 1 tolerance study evaluating intraperitoneal perfusion of Cinobufacini Injection in digestive system cancers with malignant ascites; c…
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: Clinical Study of Autologous Erythrocytes Derived MPs Packaging MTX Peritoneal Perfusion to Treat Malignant Ascites [Phase 1, Phase 2]
A Phase 1/2 study evaluating autologous erythrocyte-derived MPs delivering methotrexate via peritoneal perfusion for malignant ascites.
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CLINICAL_TRIALS trial_result · 2017-07-12Clinical Trial Update: Feasibility Study of Intraperitoneal Bevacizumab for Palliation of Intractable Malignant Ascites [Phase 1]
Phase 1 feasibility study of intraperitoneal bevacizumab for palliation of malignant ascites. The study has been terminated.
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CLINICAL_TRIALS trial_result · 2017-06-15Clinical Trial Update: Phase 1/2a Two-Arm Dose-Escalation Study of BAX69 in Subjects With Malignant Ascites of Ovarian Cancer [Phase 1, Phase 2]
A two-arm Phase 1/2a dose-escalation study of BAX69 in patients with malignant ascites due to refractory ovarian cancer has been terminated …
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CLINICAL_TRIALS trial_result · 2016-03-28Clinical Trial Update: Local mEHT + TCM Versus Intraperitoneal Chemoinfusion in Treatment of Malignant Ascites: Phase II RCT [Phase 2]
A Phase II randomized trial comparing local modulated electro-hyperthermia (mEHT) plus Traditional Chinese Medicine to intraperitoneal chemo…
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CLINICAL_TRIALS trial_result · 2015-04-13Clinical Trial Update: Bevacizumab as a Palliative Treatment for Patients With Symptomatic Malignant Ascites Due to Advanced-stage Gastrointestinal Cancers [Phase 2]
Phase 2 clinical trial evaluating bevacizumab as palliative treatment for symptomatic malignant ascites in patients with advanced gastrointe…
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CLINICAL_TRIALS trial_result · 2014-09-22Clinical Trial Update: An Early Safety and Efficacy Study of Ascites Management: Standard Paracentesis or Early Intervention With Pleurx Catheters in Patients With Malignant Ascites [NA]
This is a clinical trial update for malignant ascites comparing standard paracentesis vs early PleurX catheter intervention; the study was t…
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CLINICAL_TRIALS trial_result · 2014-08-01Clinical Trial Update: Endostar and/or Cisplatin for Treatment of Malignant Pleural Effusion or Ascites [Phase 2]
Phase 2 trial evaluating Endostar and/or Cisplatin for malignant pleural effusion or ascites has been completed.
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CLINICAL_TRIALS trial_result · 2013-10-01Clinical Trial Update: Safety and Effectiveness Study of Tumor Cell-derived Microparticles to Treat Malignant Ascites and Pleural Effusion [Phase 2]
Phase 2 safety and effectiveness study evaluating tumor cell-derived microparticles for malignant ascites and malignant pleural effusion.
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CLINICAL_TRIALS trial_result · 2013-07-15Clinical Trial Update: Cediranib as Palliative Treatment in Patients With Symptomatic Malignant Ascites or Pleural Effusion [Phase 2]
Phase 2 trial evaluating Cediranib as palliative treatment for symptomatic malignant ascites or malignant pleural effusion; the study was te…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: EF5 in Detecting Oxygen Level and Blood Vessels in Tumor Cells of Patients Undergoing Photodynamic Therapy for Intraperitoneal or Pleural Cancer [NA]
This trial evaluated EF5 as a hypoxia marker to detect oxygen levels and vasculature in tumor cells during photodynamic therapy for intraper…
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CLINICAL_TRIALS trial_result · 2013-01-01Clinical Trial Update: Study of the Effect of Intravenous AVE0005 (VEGF Trap) in Advanced Ovarian Cancer Patients With Recurrent Symptomatic Malignant Ascites [Phase 2, Phase 3]
A completed Phase 2/3 trial evaluating intravenous AVE0005 (aflibercept) in advanced ovarian cancer with recurrent symptomatic malignant asc…
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CLINICAL_TRIALS trial_result · 2012-12-11Clinical Trial Update: Study of the Trifunctional Antibody Catumaxomab to Treat Recurrent Symptomatic Malignant Ascites [Phase 2]
Phase 2 trial update evaluating trifunctional antibody catumaxomab for recurrent symptomatic malignant ascites has completed with results po…
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CLINICAL_TRIALS trial_result · 2012-10-03Clinical Trial Update: CASIMAS: Catumaxomab Safety Phase IIIb Study With Intraperitoneal Infusion in Patients With Malignant Ascites Due to Epithelial Cancers [Phase 3]
This report notes the completion of a Phase 3b safety study evaluating catumaxomab, administered intraperitoneally, for malignant ascites ca…
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CLINICAL_TRIALS trial_result · 2012-10-03Clinical Trial Update: Safety Study of Second Intraperitoneal (I.P.) Infusion Cycle of Catumaxomab in Patients With Malignant Ascites [Phase 2]
Completed Phase 2 safety study evaluating a second intraperitoneal infusion cycle of catumaxomab in patients with malignant ascites due to e…
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CLINICAL_TRIALS trial_result · 2009-02-05Clinical Trial Update: Study in EpCAM Positive Patients With Symptomatic Malignant Ascites Using Removab Versus an Untreated Control Group [Phase 2, Phase 3]
Completed phase 2/3 trial of Removab (catumaxomab) in EpCAM-positive patients with symptomatic malignant ascites, comparing with an untreate…