Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Bio-availability of Rectal Artesunate in Children With Severe Falciparum Malaria [Phase 2]
Phase 2 clinical trial updates the pharmacokinetic bio-availability of rectal artesunate in children with severe falciparum malaria.
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: A Phase Ia Clinical Trial to Assess the Safety and Immunogenicity of New Plasmodium Falciparum Malaria Vaccine Candidates ChAd63 RH5 Alone and With MVA RH5 [Phase 1]
Phase 1 trial assessing safety and immunogenicity of two malaria vaccine candidates (ChAd63 RH5 alone and with MVA RH5) targeting Plasmodium…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: A Phase I Study to Assess the Safety and Immunogenicity of ChAd63 ME-TRAP - MVA ME-TRAP Heterologous Prime-boost Vaccination Co-administered With EPI Vaccines in Gambian Infants [Phase 1]
Phase 1 trial completed evaluating safety and immunogenicity of a heterologous ChAd63 ME-TRAP/MVA ME-TRAP malaria vaccine co-administered wi…
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CLINICAL_TRIALS trial_result · 2015-11-30Clinical Trial Update: Time to Become Negative of Three Rapid Diagnostic Tests for Malaria
A completed clinical trial evaluating the time to negativity for three rapid diagnostic tests used to detect falciparum malaria.
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CLINICAL_TRIALS trial_result · 2015-11-30Clinical Trial Update: Acute vs. Delayed Iron: Effect on Red Cell Iron Incorporation in Severe Malaria [NA]
A completed clinical trial comparing acute versus delayed iron administration and its effect on red cell iron incorporation in severe malari…
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CLINICAL_TRIALS trial_result · 2015-11-30Clinical Trial Update: Efficacy of Three ACTs for the Treatment of Falciparum Malaria in Maradi Niger [Phase 4]
A Phase 4 study update reports the efficacy of three artemisinin-based combination therapies for falciparum malaria in Maradi, Niger; the tr…
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CLINICAL_TRIALS trial_result · 2015-11-18Clinical Trial Update: Safety, Attenuation and Immunogenicity of GAP3KO Administered Via A Stephensi Mosquitoes [Phase 1]
Phase 1 trial evaluating safety, attenuation, and immunogenicity of the GAP3KO malaria vaccine delivered via Anopheles stephensi mosquitoes;…
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CLINICAL_TRIALS withdrawal · 2015-11-13Clinical Trial Update: Prednisone Plus Chloroquine for the Treatment of Hyper-reactive Malarial Splenomegaly [Phase 3]
A Phase 3 clinical trial evaluating prednisone plus chloroquine for hyper-reactive malarial splenomegaly has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-10-29Clinical Trial Update: Chloroquine for Malaria in Pregnancy [Phase 3]
A Phase 3 clinical trial evaluating chloroquine for malaria in pregnancy completed, with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-10-15Clinical Trial Update: A Safety, Tolerability, Pharmacokinetic and Efficacy Study of Azithromycin Plus Piperaquine as Presumptive Treatment in Pregnant PNG Women [Phase 4]
Phase 4 study assessing the safety, tolerability, pharmacokinetics, and efficacy of azithromycin plus piperaquine as presumptive malaria tre…
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CLINICAL_TRIALS trial_result · 2015-10-07Clinical Trial Update: A Phase Ib Induced Malaria Infection Study With the Combination of OZ439 and DSM265 [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/2 study evaluating the safety and potential efficacy of the OZ439 and DSM265 combination in ind…
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CLINICAL_TRIALS trial_result · 2015-10-01Clinical Trial Update: A Trial of the Efficacy of Artesunate and Three Quinine Regimens in the Treatment of Severe Malaria in Children at the Ebolowa Regional Hospital - Cameroon [Phase 3]
A Phase 3 trial evaluated artesunate with three quinine regimens for treating severe malaria in children at a Cameroonian hospital. The stud…
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CLINICAL_TRIALS trial_result · 2015-09-24Clinical Trial Update: School-Based Treatment With ACT to Reduce Transmission [Phase 4]
A Phase 4 trial evaluating school-based treatment with artemisinin-based combination therapy to reduce malaria transmission has completed.
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FDA approval · 2015-09-21FDA Approved: DOXYCYCLINE HYCLATE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for Doxycycline Hyclate by Hikma Pharmaceuticals USA Inc., indicating a change to the product's labe…
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CLINICAL_TRIALS trial_result · 2015-09-18Clinical Trial Update: The Synergistic Effects of Home-management and Intermittent Preventive Treatment of Malaria in Children [Phase 4]
This Phase 4 clinical trial update assesses the potential synergistic effect of home-based management and intermittent preventive treatment …
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CLINICAL_TRIALS trial_result · 2015-09-18Clinical Trial Update: Seasonal Malaria Chemoprevention Versus Home Management of Malaria in Children Under 5 Years in Ghana [Phase 4]
Phase 4 trial in Ghana comparing seasonal malaria chemoprevention with sulfadoxine-pyrimethamine and amodiaquine to home management of malar…
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CLINICAL_TRIALS trial_result · 2015-09-03Clinical Trial Update: A Study to Assess Efficacy, Safety of KAE609 in Adult Patients With Acute Malaria Mono-infection [Phase 2]
Phase 2 study evaluating the efficacy and safety of KAE609 (cipargamin) in adults with acute malaria mono-infection completed, with results …
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FDA approval · 2015-09-02FDA Approved: COARTEM — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for COARTEM (artemether and lumefantrine) submitted by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Low Dose Primaquine for Clearance of Gametocytes [Phase 2, Phase 3]
Phase 2/Phase 3 trial evaluating low-dose primaquine to clear gametocytes in malaria has completed.
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CLINICAL_TRIALS trial_result · 2015-08-31Clinical Trial Update: Proof-of-Concept Study of MSP3-LSP Vaccine to Protect Against Malaria in Africa [Phase 2]
This is a completed Phase 2 proof-of-concept trial evaluating the MSP3-LSP malaria vaccine in Africa.
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Efficacy, Safety, Tolerability and Pharmacokinetics of KAF156 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection [Phase 2]
Phase 2 study evaluating KAF156 (ganaplacide) in adults with acute, uncomplicated malaria showed efficacy, tolerability and pharmacokinetics…
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CLINICAL_TRIALS trial_result · 2015-08-10Clinical Trial Update: Target Antigens Induced by Plasmodium Falciparum Sporozoite Immunization Under Chemoprophylaxis [NA]
A completed clinical trial investigating antigens targeted by Plasmodium falciparum sporozoite immunization under chemoprophylaxis for malar…
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CLINICAL_TRIALS trial_result · 2015-08-07Clinical Trial Update: Community Point Distribution of Insecticide Treated Bed Nets [NA]
The document reports the completion of a clinical trial evaluating community distribution of insecticide-treated bed nets for malaria preven…
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CLINICAL_TRIALS trial_result · 2015-08-04Clinical Trial Update: Chemopreventive Therapy for Malaria in Ugandan Children [Phase 3]
A Phase 3 trial evaluating chemopreventive therapy for malaria in Ugandan children has completed, and its results have been posted.
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CLINICAL_TRIALS trial_result · 2015-08-03Clinical Trial Update: In Vivo and in Vitro Efficacy of Antimalarial Treatments in Children in Burkina Faso [Phase 4]
Phase 4 study evaluating the in vivo and in vitro efficacy of antimalarial treatments in children in Burkina Faso.