Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-08-01Clinical Trial Update: A FIH Study to Investigate the Safety, Tolerability and PK of P218 [Phase 1]
Phase 1 trial update for a first-in-human study evaluating safety, tolerability, and pharmacokinetics of P218 in malaria.
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CLINICAL_TRIALS trial_result · 2019-07-29Clinical Trial Update: Malaria Vaccine Safety and Immunogenicity Study in Healthy Adults [Phase 2]
Phase 2 trial evaluating safety and immunogenicity of a malaria vaccine in healthy adults completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-07-24Clinical Trial Update: Efficacy, Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Evaluating Different Dose Schedules in a Sporozoite Challenge Model in Healthy Malaria-naïve Adults [Phase 2]
Phase 2 trial assessing efficacy, immunogenicity, and safety of different dose schedules for GSK's malaria vaccine in malaria-naïve adults; …
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CLINICAL_TRIALS trial_result · 2019-06-26Clinical Trial Update: Cohort Event Monitoring Study of Pyramax® [Phase 4]
Phase 4 cohort event monitoring study of Pyramax for malaria caused by Plasmodium falciparum has completed.
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CLINICAL_TRIALS trial_result · 2019-05-29Clinical Trial Update: Study of VMP001 and AS01B (Adjuvant Formulation) in Healthy Malaria-Naïve Adults [Phase 1, Phase 2]
Clinical trial update for a malaria vaccine study (VMP001 with AS01B adjuvant) in healthy adults shows completed Phase 1/2 with posted resul…
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CLINICAL_TRIALS research · 2019-05-10Clinical Trial Update: Clinical and Biological Efficacy of Mirasol-treated Fresh Whole Blood for the Prevention of Transfusion-transmitted Malaria [NA]
A completed clinical trial evaluating Mirasol-treated fresh whole blood for preventing transfusion-transmitted malaria; results posted in 20…
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CLINICAL_TRIALS trial_result · 2019-04-19Clinical Trial Update: Safety, Tolerability and Efficacy of PfSPZ Vaccine in Healthy Children and Infants 5 Months - 9 Years Living in Kenya [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating the PfSPZ vaccine for safety, tolerability, and efficacy in healthy children and infants aged 5 month…
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: A Randomized Controlled Trial on Malaria Primaquine Treatment in Timika, Indonesia (TRIPI) [Phase 4]
A Phase 4 randomized controlled trial evaluating primaquine treatment for uncomplicated malaria in Timika, Indonesia has completed.
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CLINICAL_TRIALS research · 2019-03-05Clinical Trial Update: Reducing the Burden of Malaria in HIV-Infected Pregnant Women and Their HIV-Exposed Children (PROMOTE-BC2) [Phase 3]
Phase 3 trial evaluating strategies to reduce malaria burden in HIV-infected pregnant women and HIV-exposed children; study completed with r…
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FDA approval · 2019-02-22FDA Approved: MALARONE — Supplemental Application (GlaxoSmithKline LLC)
The FDA approved a supplemental application for Malarone, a combination of atovaquone and proguanil hydrochloride, from GlaxoSmithKline LLC.
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CLINICAL_TRIALS trial_result · 2019-02-11Clinical Trial Update: Spirulina Supplementation and Infant Growth, Morbidity and Motor Development [NA]
Completed clinical trial evaluating spirulina supplementation and its effects on infant growth, morbidity, and motor development.
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CLINICAL_TRIALS trial_result · 2019-02-05Clinical Trial Update: The Effectiveness of Non-Pyrethroid Insecticide-Treated Durable Wall Liners as a Method for Malaria Control in Endemic Rural Tanzania [Phase 3]
Phase 3 trial evaluating non-pyrethroid insecticide-treated durable wall liners for malaria control in rural Tanzania was terminated.
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CLINICAL_TRIALS trial_result · 2019-02-04Clinical Trial Update: Comparing PI-Based to a nNRTI-based ART for Clearance of Plasmodium Falciparum Parasitemia in HIV-Infected [Phase 1, Phase 2]
Phase 1/2 trial comparing protease inhibitor–based ART to a non-nucleoside reverse transcriptase inhibitor–based ART for clearance of Plasmo…
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Sequential Optimization of Dose and Schedule of PfSPZ Vaccine [Phase 1]
Phase 1 trial completed to evaluate sequential optimization of dose and schedule for the PfSPZ Vaccine in malaria. The study aimed to identi…
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Time to Infection With Malaria Parasites
This clinical trial update summarizes a completed study on the time to infection with Plasmodium falciparum malaria parasites.
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: Plasmodium Resistance in A. Gambiae
Completed clinical trial update examining Plasmodium resistance in Anopheles gambiae in the context of malaria (Plasmodium falciparum).
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: PfSPZ Challenge in Non-immune Adults in Baltimore, USA [Phase 1]
Phase 1 clinical trial of PfSPZ Challenge in non-immune adults in Baltimore has completed.
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CLINICAL_TRIALS trial_result · 2019-01-16Clinical Trial Update: Safety and Immunogenicity of GSK Biologicals' Investigational Malaria Vaccine in HIV Infected Infants and Children [Phase 3]
Phase 3 trial assessing safety and immunogenicity of GSK's investigational malaria vaccine in HIV-infected infants and children completed wi…
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FDA approval · 2019-01-15FDA Approved: HYDROXYCHLOROQUINE SULFATE — Original Application (Rising Pharma Holdings, Inc.)
The FDA approved a generic hydroxychloroquine sulfate product under an Original Application from Rising Pharma Holdings, Inc. for use in tre…
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CLINICAL_TRIALS trial_result · 2019-01-04Clinical Trial Update: Repeat Ivermectin Mass Drug Administrations for Control of Malaria: a Pilot Safety and Efficacy Study [Phase 2, Phase 3]
Pilot safety and efficacy study evaluating repeat mass drug administrations of ivermectin for malaria control, completed with results posted…
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CLINICAL_TRIALS trial_result · 2018-12-28Clinical Trial Update: HIV Protease Inhibitors for the Prevention of Malaria in Ugandan Children [Phase 3]
Phase 3 trial evaluating HIV protease inhibitors for prevention of malaria in Ugandan children has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-12-26Clinical Trial Update: Efficacy, Safety and Immunogenicity Study of GlaxoSmithKline(GSK) Biologicals' Candidate Malaria Vaccine 257049 in the Sporozoite Challenge Model in Healthy Malaria-naïve Adults [Phase 2]
Phase 2 trial assessing efficacy, safety, and immunogenicity of a GlaxoSmithKline malaria vaccine candidate in healthy malaria-naïve adults;…
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CLINICAL_TRIALS trial_result · 2018-11-26Clinical Trial Update: Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America [Phase 1, Phase 2]
Phase I/II clinical trial update for a malaria vaccine in adults in the United States (completed; results posted).
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FDA approval · 2018-11-21FDA Approved: ATOVAQUONE — Original Application (Glenmark Pharmaceuticals Inc., USA)
FDA approved the original application for atovaquone as a generic drug, confirming its approved uses for Pneumocystis jirovecii pneumonia, p…
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CLINICAL_TRIALS trial_result · 2018-11-14Clinical Trial Update: Reducing the Burden of Malaria in HIV-uninfected Pregnant Women and Infants [Phase 3]
Phase 3 trial results evaluating strategies to reduce malaria burden in HIV-uninfected pregnant women and their infants were posted. The stu…