Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-11-12Clinical Trial Update: Drug Interaction Study Between Atovaquone and Antiretroviral Agents in HIV-1 Infected Patients [Phase 4]
A Phase 4 trial update evaluating drug interaction between atovaquone and antiretroviral agents in HIV-1 infected patients completed.
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CLINICAL_TRIALS trial_result · 2020-11-12Clinical Trial Update: Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: the TESTsmART Trial AIM 1 [NA]
Clinical trial update for TESTsmART trial AIM 1 focusing on malaria diagnostic testing and subsidies for ACTs in retail settings; study comp…
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CLINICAL_TRIALS trial_result · 2020-11-03Clinical Trial Update: Malaria High-Risk Populations in Namibia [Phase 4]
Phase 4 clinical trial update focused on malaria in high-risk populations in Namibia has completed.
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CLINICAL_TRIALS trial_result · 2020-11-02Clinical Trial Update: A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) Malaria [Phase 2]
Phase 2 pediatric pharmacokinetics, safety, and efficacy study of tafenoquine for Plasmodium vivax malaria has been completed with results p…
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria [Phase 2]
Phase 2 trial evaluating ferroquine and artefenomel for uncomplicated Plasmodium falciparum malaria was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-09-25Clinical Trial Update: Safety of KAE609 in Adults With Uncomplicated Plasmodium Falciparum Malaria. [Phase 2]
Phase 2 trial assessing safety of KAE609 in adults with uncomplicated Plasmodium falciparum malaria has completed and results posted.
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CLINICAL_TRIALS research · 2020-08-18Clinical Trial Update: Epidemiology Study of Malaria Transmission Intensity in Africa [NA]
A completed epidemiology study assessing malaria transmission intensity in Africa, with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: Efficacy and Safety Study of Tafenoquine (TQ) Co-administered With Dihydroartemisinin-piperaquine (DHA-PQP) for the Radical Cure of Plasmodium Vivax (P. Vivax) Malaria [Phase 3]
Phase 3 trial evaluating tafenoquine co-administered with dihydroartemisinin-piperaquine for radical cure of Plasmodium vivax malaria has co…
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: Dose Escalation PfSPZ-CVac [Phase 1]
Phase 1 dose-escalation trial of PfSPZ-CVac for malaria has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-07-23Clinical Trial Update: Targeted Indoor Residual Spraying Against Malaria [Phase 4]
Phase 4 clinical trial update on targeted indoor residual spraying for malaria; study completed.
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: Evaluation of Reactive Focal Mass Drug Administration (rfMDA) +/- Reactive Focal Vector Control (RAVC) in Namibia [Phase 3]
Phase 3 trial evaluating reactive focal mass drug administration with or without reactive focal vector control for malaria in Namibia has co…
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CLINICAL_TRIALS trial_result · 2020-06-11Clinical Trial Update: Safety, Tolerability and Pharmacokinetic Profile of Ascending Oral Doses of MMV390048, Part A [Phase 1]
Phase 1 trial update on ascending oral doses of MMV390048 focusing on safety, tolerability, and pharmacokinetics in malaria patients; result…
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CLINICAL_TRIALS trial_result · 2020-06-09Clinical Trial Update: Longitudinal Antimalarial Combinations in Uganda [Phase 3]
Phase 3 clinical trial update on longitudinal antimalarial combinations conducted in Uganda, completed.
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CLINICAL_TRIALS trial_result · 2020-06-09Clinical Trial Update: MMV390048 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Participants [Phase 1]
Phase 1 trial evaluating MMV390048 for early blood-stage infection of Falciparum malaria in healthy participants; study terminated with resu…
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CLINICAL_TRIALS trial_result · 2020-06-09Clinical Trial Update: Evaluate the Safety and Efficacy of Plasmodium Falciparum Malaria Protein 010 (FMP010) Administered With Adjuvant AS01B [Phase 1]
Phase 1 trial evaluating safety and efficacy of FMP010 malaria protein with AS01B adjuvant completed with posted results in 2020.
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CLINICAL_TRIALS trial_result · 2020-06-05Clinical Trial Update: A Study to Characterise the Antimalarial and Transmission Blocking Activity of a Single Dose of DSM265 or OZ439 in Healthy Subjects With Induced Blood Stage Plasmodium Falciparum or Plasmodium Vivax Infection [Phase 1, Phase 2]
Phase 1/2 trial evaluating single-dose DSM265 or OZ439 for antimalarial activity and transmission-blocking in healthy subjects with induced …
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CLINICAL_TRIALS research · 2020-06-04Clinical Trial Update: Post-discharge Malaria Chemoprevention(PMC) Study [Phase 3]
A Phase 3 trial update on post-discharge malaria chemoprevention following severe malaria hospitalization is reported as completed.
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CLINICAL_TRIALS trial_result · 2020-05-26Clinical Trial Update: Effectiveness of OZ439 as a Gametocytocidal and Transmission Blocking Agent [Phase 1, Phase 2]
Phase 1/2 trial update evaluating OZ439 as a gametocytocidal and transmission-blocking agent for malaria; results posted after completion.
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CLINICAL_TRIALS trial_result · 2020-05-26Clinical Trial Update: Experimental Falciparum Transmission to Anopheles [Phase 1]
Phase 1 trial update on an experimental intervention addressing transmission of malaria to Anopheles mosquitoes; study completed with posted…
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CLINICAL_TRIALS trial_result · 2020-05-15Clinical Trial Update: A Study to Evaluate the Efficacy, Immunogenicity and Safety in a Sporozoite Challenge Model of a Fractional Booster Dose of GSK Biologicals' Candidate Malaria Vaccine Administered to Previously Vaccinated Healthy Malaria-naïve Adults [Phase 2]
Phase 2 clinical trial evaluating a fractional booster dose of GlaxoSmithKline's malaria vaccine in previously vaccinated malaria-naïve adul…
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CLINICAL_TRIALS trial_result · 2020-05-01Clinical Trial Update: In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children (MEFI_III) [Phase 4]
Phase 4 trial update evaluating in vivo efficacy of artemether-lumefantrine and amodiaquine-artesunate for malaria in Mozambican children ha…
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FDA approval · 2020-04-30FDA Approved: CHLOROQUINE PHOSPHATE — Supplemental Application (Amneal Pharmaceuticals of New York LLC)
The FDA approved a supplemental application for chloroquine phosphate from Amneal Pharmaceuticals of New York LLC under ANDA 080880.
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FDA approval · 2020-04-28FDA Approved: CHLOROQUINE PHOSPHATE — Supplemental Application (Amneal Pharmaceuticals of New York LLC)
FDA approves Amneal Pharmaceuticals of New York LLC's supplemental application for chloroquine phosphate, granting approval of the generic p…
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FDA approval · 2020-04-09FDA Approved: HYDROXYCHLOROQUINE SULFATE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for hydroxychloroquine sulfate from Aurobindo Pharma Limited.
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FDA approval · 2020-04-01FDA Approved: HYDROXYCHLOROQUINE SULFATE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for hydroxychloroquine sulfate from Aurobindo Pharma Limited.