Malaria in Pregnancy
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics [Phase 4]
A Phase 4 trial from Duke University is investigating a high-sensitivity rapid malaria test in early pregnancy to improve neonatal health ou…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Sulfadoxine-pyrimethamine Plus Dihydroartemisinin-piperaquine for Intermittent Preventive Treatment in Pregnancy [Phase 3]
This clinical trial update describes a Phase 3 study evaluating sulfadoxine-pyrimethamine plus dihydroartemisinin-piperaquine for intermitte…
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CLINICAL_TRIALS other · 2024-08-27Clinical Trial Update: Plasmodium Falciparum Genomic Intelligence in Mozambique
This is a completed clinical trial in Mozambique investigating Plasmodium falciparum genomic intelligence for malaria, including malaria in …
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CLINICAL_TRIALS research · 2024-08-26Clinical Trial Update: Malaria Molecular Surveillance in Mozambique (Phase 2)
Phase 2 malaria molecular surveillance trial in Mozambique is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-03-15Clinical Trial Update: Intermittent Preventive Treatment With Dihydroartemisinin-piperaquine in Papua, Indonesia [Phase 4]
Phase 4 trial update on intermittent preventive treatment with dihydroartemisinin-piperaquine for malaria in pregnancy has completed.
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CLINICAL_TRIALS trial_result · 2023-08-22Clinical Trial Update: Improving PRegnancy Outcomes With PReVEntive Therapy in Africa-2 (IMPROVE-2) [Phase 3]
Phase 3 trial IMPROVE-2 investigated preventive therapy to improve pregnancy outcomes in Africa; study completed.
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CLINICAL_TRIALS trial_result · 2022-11-04Clinical Trial Update: Comparison of ISTp- PYRAMAX-US-RDT to IPTp-SP to Prevent Malaria in Pregnant Women in DRC (ULTRAPYRAPREG) [Phase 3]
Phase 3 trial comparing ISTp-PYRAMAX-US-RDT to IPTp-SP for malaria prevention in pregnant women in the Democratic Republic of Congo has comp…
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CLINICAL_TRIALS trial_result · 2022-06-27Clinical Trial Update: Improving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa [Phase 3]
A Phase 3 trial updating on intermittent preventive treatment for malaria in pregnancy in Africa has completed.
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CLINICAL_TRIALS trial_result · 2022-05-04Clinical Trial Update: A Novel Regimen to Prevent Malaria and STI in Pregnant Women With HIV [Phase 2]
Phase 2 trial update on a novel regimen aimed at preventing malaria and sexually transmitted infections in pregnant women with HIV; study co…
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CLINICAL_TRIALS trial_result · 2021-07-26Clinical Trial Update: Efficacy and Safety of IPTp-DP Versus IPTp-SP in Malawi [Phase 3]
Phase 3 trial comparing IPTp-DP to IPTp-SP in pregnant individuals with malaria in Malawi completed.
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CLINICAL_TRIALS research · 2021-04-15Clinical Trial Update: Acceptability and Feasibility in the Context of the IMPROVE Trial in Kenya [Phase 4]
Phase 4 trial update focused on acceptability and feasibility of the IMPROVE trial in Kenya (Malaria in Pregnancy, adherence, treatment).
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CLINICAL_TRIALS trial_result · 2020-11-30Clinical Trial Update: Efficacy of Antifolates Against Malaria in HIV-infected Pregnant Women and the Emergence of Induced Resistance in Plasmodium Falciparum [Phase 3]
Phase 3 trial assessing antifolates for malaria in HIV-infected pregnant women and reporting emergence of induced resistance in Plasmodium f…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Safety and Immunogenicity of the Placental Malaria Vaccine Candidate PAMVAC Variously Adjuvanted [Phase 1]
This Phase 1 trial assessed the safety and immunogenicity of the placental malaria vaccine candidate PAMVAC with various adjuvants in antepa…
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CLINICAL_TRIALS trial_result · 2017-03-06Clinical Trial Update: Efficacy of Intermittent Screening and Treatment or Intermittent Preventive Treatment (IPT) With Dihydroartemisinin-Piperaquine, Versus IPT With Sulfadoxine-Pyrimethamine for the Control of Malaria in Pregnancy in Kenya [Phase 4]
A Phase 4 trial in Kenya compared intermittent preventive treatment with dihydroartemisinin-piperaquine to intermittent preventive treatment…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Influence of Chloroquine on HIV Viral Load Among Pregnant Women in Uganda [NA]
A completed clinical trial evaluated whether chloroquine influences HIV viral load among pregnant women in Uganda.
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CLINICAL_TRIALS trial_result · 2016-03-14Clinical Trial Update: Safe and Efficacious Artemisinin-based Combination Treatments for African Pregnant Women With Malaria [Phase 3]
Phase 3 trial evaluating artemisinin-based combination therapies for treating malaria in pregnant African women; the study has completed.
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: Efficacy,Safety and Tolerability of Dihydroartemisinin-Piperaquine for Uncomplicated Malaria in Pregnancy in Ghana [Phase 3]
Phase 3 clinical trial update assessing the efficacy, safety, and tolerability of dihydroartemisinin-piperaquine for uncomplicated malaria i…
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CLINICAL_TRIALS trial_result · 2016-01-18Clinical Trial Update: Daily Co-trimoxazole Prophylaxis to Prevent Malaria in Pregnancy [Phase 3]
Phase 3 trial evaluating daily co-trimoxazole prophylaxis to prevent malaria in pregnancy was terminated.
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CLINICAL_TRIALS research · 2015-04-23Clinical Trial Update: Malaria Rapid Diagnostic Tests (RDTs) in Pregnancy: Detection of Placental Malaria
Update on a trial evaluating malaria rapid diagnostic tests during pregnancy for detecting placental malaria; the current trial status is un…
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CLINICAL_TRIALS withdrawal · 2015-03-05Clinical Trial Update: Sulphadoxine-Pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Uganda [Phase 4]
Phase 4 trial of sulfadoxine-pyrimethamine for intermittent preventive treatment of malaria in pregnancy in Uganda has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-01-26Clinical Trial Update: Evaluate Parasitological Clearance Rates And Pharmacokinetics Of The Combination Of Azithromycin And Chloroquine In Asymptomatic Pregnant Women With Falciparum Parasitemia In Africa [Phase 3]
Phase 3 trial evaluating the combination of azithromycin and chloroquine for parasitological clearance and pharmacokinetics in asymptomatic …
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CLINICAL_TRIALS trial_result · 2014-09-05Clinical Trial Update: Evaluate Azithromycin Plus Chloroquine And Sulfadoxine Plus Pyrimethamine Combinations For Intermittent Preventive Treatment Of Falciparum Malaria Infection In Pregnant Women In Africa [Phase 3]
Phase 3 trial evaluating azithromycin plus chloroquine and sulfadoxine plus pyrimethamine for intermittent preventive treatment of falciparu…
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CLINICAL_TRIALS trial_result · 2013-10-24Clinical Trial Update: Establishing Effectiveness of Daily Co-trimoxazole Prophylaxis For Prevention of Malaria in Pregnancy [Phase 3]
A Phase 3 trial evaluated daily co-trimoxazole prophylaxis for preventing malaria in pregnancy, including HIV-infected women. The study has …
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CLINICAL_TRIALS trial_result · 2013-02-06Clinical Trial Update: Assessment of Sulphadoxine-pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Malawi
A completed clinical trial evaluating sulfadoxine-pyrimethamine for intermittent preventive treatment of malaria in pregnancy in Malawi.
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: Prevention of Pregnancy-associated Malaria in HIV-infected Women: Cotrimoxazole Prophylaxis Versus Mefloquine [Phase 3]
Phase 3 trial comparing cotrimoxazole prophylaxis to mefloquine for preventing malaria during pregnancy in HIV-infected women; the study has…