Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-10-28Clinical Trial Update: Effective of Transcranial Magnetic Stimulation (TMS) vs Treatment as Usual for First-Episode Depression in Adults [Phase 4]
This ClinicalTrials.gov update describes a Phase 4 study comparing Transcranial Magnetic Stimulation (TMS) to treatment as usual for first-e…
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CLINICAL_TRIALS trial_result · 2024-10-26Clinical Trial Update: EEG Characteristics in ECT [EARLY_Phase 1]
An early-phase trial evaluating EEG characteristics during electroconvulsive therapy, including direct current EEG and ketamine administrati…
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CLINICAL_TRIALS trial_result · 2024-10-26Clinical Trial Update: Online Yoga for Improving the Well-being of Desk-based Workers [NA]
A completed clinical trial evaluating online yoga to improve well-being and reduce stress, depression, and anxiety among desk-based workers.
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CLINICAL_TRIALS other · 2024-10-26Clinical Trial Update: Treating Loneliness In The Older Adult With Depression With tDCS [NA]
A clinical trial update indicating that transcranial direct current stimulation (tDCS) is being studied for loneliness in older adults with …
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FDA approval · 2024-10-25FDA Approved: ESCITALOPRAM OXALATE — Supplemental Application (Quallent Pharmaceuticals Health LLC)
The FDA approved a supplemental application for escitalopram oxalate from Quallent Pharmaceuticals Health LLC, a generic antidepressant.
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Psilocybin vs Escitalopram for Major Depressive Disorder: Comparative Mechanisms [Phase 2]
Phase 2 randomized trial comparing psilocybin to escitalopram for major depressive disorder was completed with results posted on 2024-10-24.
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Voice Changes During ECT
This update summarizes a completed clinical trial evaluating voice changes during electroconvulsive therapy (ECT) for depressive disorders. …
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Impact of Modifiable Psychosocial Factors on Veterans' Long-term Trajectories of Functioning and Quality of Life
A VA-sponsored clinical trial completed its assessment of how modifiable psychosocial factors affect long-term functioning and quality of li…
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Cognitive Behavioral Therapy for Insomnia with RTMS [NA]
Completed clinical trial evaluating cognitive behavioral therapy for insomnia using repetitive transcranial magnetic stimulation (RTMS) in p…
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FDA approval · 2024-10-23FDA Approved: BUPROPION HYDROCHLORIDE XL — Supplemental Application (Actavis Pharma, Inc.)
FDA approved a supplemental ANDA for Bupropion hydrochloride extended-release (XL) from Actavis Pharma, confirming the generic product's app…
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CLINICAL_TRIALS research · 2024-10-23Clinical Trial Update: Efficacy of a Mobile Phone App for Depression and Anxiety in College Students [NA]
This update reports that a University of Chile-sponsored mobile app trial evaluating efficacy for depressive and anxiety symptoms in college…
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: Depression, Anxiety, and Stress in a Sample of Resident Doctors in Upper Egypt
This Assiut University clinical trial is evaluating depression and anxiety among resident doctors in Upper Egypt; the study is not yet recru…
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: Mood Disorders in Multiple Sclerosis Patients
This clinical trial update confirms that a study evaluating mood disorders in patients with multiple sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: An Adaptive Intervention for Depression Among Latinos Living With HIV [NA]
A completed clinical trial evaluating an adaptive intervention for depression among Latinos living with HIV, with results posted on 2024-10-…
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Study to Compare the Use of a Behavioral Health App Versus Care As Usual for 16-22 Year Olds with Depression [NA]
A completed clinical trial comparing a behavioral health app to care as usual for youths aged 16-22 with depression.
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: A Trial of "Opening Doors to Recovery" for Persons With Serious Mental Illnesses [NA]
The clinical trial 'Opening Doors to Recovery' for persons with serious mental illnesses has completed and posted results, sponsored by the …
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: Delivering ICBT to Address Mental Health Challenges in Correctional Officers and Other Public Safety Personnel [NA]
This clinical trial update reports completion of a study delivering internet-delivered cognitive behavioral therapy (ICBT) to address mental…
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: Remote Coaching for Supporting the Implementation of Depression Care in Primary Care in Rural India [NA]
A completed clinical trial evaluating remote coaching to support the implementation of depression care in primary care settings in rural Ind…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: Depression Return to Work Intervention [NA]
A trial evaluating a Depression Return to Work Intervention sponsored by Inspiration at Work has completed.
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: Comparing Clinical Decision-making of AI Technology to a Multi-professional Care Team in ECBT for Depression [NA]
This clinical trial compares AI-driven clinical decision-making to a multi-professional care team in Enhanced CBT for Depression and is curr…
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FDA approval · 2024-10-17FDA Approved: BUPROPION HYDROCHLORIDE — Original Application (Granules Pharmaceuticals Inc.)
FDA approved Granules Pharmaceuticals' generic bupropion hydrochloride through an original New Drug Application (ANDA), confirming its use f…
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: Identifying and Treating Depression in Hemodialysis Patients [Phase 4]
Phase 4 clinical trial update reporting results from a study on identifying and treating depression in patients receiving hemodialysis has b…
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: The Role of Dopamine Metabolism in the Antidepressant Effects of Sleep Deprivation and Sertraline in Depressed Patients [Phase 1, Phase 2]
This completed Phase 1/2 trial examined whether sleep deprivation enhances the antidepressant effects of sertraline via dopamine metabolism …
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: Effectiveness and Tolerability of аgomelatine in the Treatment of Patients With Depression After SARS-CoV-2 (TELESPHOR)
A completed clinical trial assessed the effectiveness and tolerability of agomelatine for depression after SARS-CoV-2 infection. Results wer…
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: Feasibility and Acceptability of W-GenZD vs CBT-light Teletherapy for Adolescents Seeking Mental Health Services [NA]
The update reports on the feasibility and acceptability of W-GenZD versus CBT-light teletherapy for adolescents with depression and anxiety,…