Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: PEERS Using Peer Mentors to Deliver Depression Care [NA]
The PEERS trial, which uses peer mentors to deliver depression care, has completed and posted its results.
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: Initiating Ketamine in Acutely Suicidal Patients in the Emergency Department [Phase 3]
A Phase 3 trial evaluating ketamine for acutely suicidal patients in the emergency department was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: Evaluation of a Mobile Therapy for Elevated Depressive Symptoms [NA]
A completed clinical trial from the Medical University of South Carolina evaluated a mobile therapy for depressive symptoms/depression, with…
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FDA approval · 2024-11-18FDA Approved: QUETIAPINE FUMARATE — Supplemental Application (Macleods Pharmaceuticals Limited)
The FDA approved a supplemental application for Quetiapine fumarate by Macleods Pharmaceuticals Limited, enabling a generic version of the a…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Synaptic Imaging and Network Activity in Treatment Resistant Depression [NA]
King's College London completed a clinical trial investigating synaptic imaging and network activity in treatment-resistant depression.
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: The Effect of Soluble Epoxide Hydrolase (SEH) on Depression
A completed clinical trial evaluated the effect of a soluble epoxide hydrolase inhibitor on Major Depressive Disorder.
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Maternal Depression Treatment in HIV [Phase 2, Phase 3]
A clinical trial program evaluating treatments for maternal depression in HIV-positive individuals completed Phase 2 and Phase 3, with resul…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Online Cognitive Behavioral Therapy for Depressive Symptoms in Rural Patients with Cardiac Disease [NA]
A completed clinical trial evaluating online cognitive behavioral therapy for depressive symptoms in rural patients with cardiovascular dise…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Behavioral Activation + Cognitive Processing Therapy for PTSD and Comorbid MDD [NA]
A completed clinical trial evaluated Behavioral Activation plus Cognitive Processing Therapy for individuals with posttraumatic stress disor…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Personalized Feedback for Distress Intolerant Smokers [NA]
This completed clinical trial from the University of Houston studied personalized feedback for distress intolerant smokers. Results were pos…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Interleaved TMS-fMRI in Ultra-treatment Resistant Depression [NA]
An ongoing clinical trial at Sunnybrook Health Sciences Centre is evaluating interleaved transcranial magnetic stimulation with functional M…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Trial of Surf and Hike Therapy for Major Depressive Disorder [NA]
The document reports a completed clinical trial evaluating Surf and Hike Therapy for major depressive disorder.
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: European Deep Brain Stimulation (DBS) Depression Study [NA]
Completed results from a European deep brain stimulation trial for major depressive disorder. Results have been posted.
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Reward Function and Therapy for Late-Life Depression [NA]
Clinical trial update for a study on reward function and therapy in late-life major depressive disorder; the study is completed and results …
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Effect of Ketamine on Neurological Activity as Measured by Electroencephalogram (EEG)
This clinical trial evaluated the effect of ketamine on brain activity measured by EEG in individuals with treatment-resistant depression. T…
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FDA approval · 2024-11-12FDA Approved: ARIPIPRAZOLE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for a generic form of aripiprazole from Aurobindo Pharma Limited.
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: DPA-714 and FDG PET/MRI in Depression [NA]
A recruiting clinical trial at The First Affiliated Hospital of Dalian Medical University studies DPA-714 with FDG PET/MRI in depression.
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: PAPR: PAP + MBSR for Front-line Healthcare Provider COVID-19 Related Burnout [Phase 1]
Phase 1 clinical trial evaluating PAP plus mindfulness-based stress reduction (MBSR) for frontline healthcare workers experiencing COVID-19-…
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Wraparound for High-risk Families with Substance Use Disorders: Examining Family, Child, and Parent Outcomes [NA]
Completed clinical trial evaluating wraparound services for high-risk families with substance use disorders, examining family, child, and pa…
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Suicide Prevention Among Recipients of Care [NA]
This is a completed clinical trial update (NCT04893447) evaluating suicide prevention among recipients of care, with focus on associated men…
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: Group Depression Treatment for Autistic Youth [NA]
This clinical trial update reports completion of a study evaluating a group-based depression treatment for autistic youth; results have been…
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: The Effects of Exercise on Gut Bacteria, Mood and Cognition in Depression [NA]
A clinical trial evaluating the effects of exercise on gut bacteria, mood, and cognition in people with depression; currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: Adolescent Depression: Video Ads on Instagram [NA]
A Yale University–led trial examining adolescent depression and stigma using Instagram video ads has completed. The document does not indica…
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: High- vs Low-Frequency Exercise for Depression in Adolescents [NA]
Clinical trial evaluating high- versus low-frequency exercise for depressive symptoms in adolescents has completed.
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FDA approval · 2024-11-07FDA Approved: SERTRALINE HYDROCHLORIDE — Supplemental Application (Accord Healthcare, Inc.)
FDA approved a supplemental application for Accord Healthcare's sertraline hydrochloride, a generic version of sertraline, maintaining the u…