Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Effects of Amygdala Neurofeedback on Depressive Symptoms [NA]
A terminated clinical trial studied amygdala neurofeedback for depressive symptoms in Major Depressive Disorder; results have been posted.
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Study on the Treatment of Depression with Jieyu Chufan Capsules [Phase 4]
This is a Phase 4 randomized, double-blind, placebo-controlled multicenter clinical trial evaluating Jieyu Chufan Capsules for major depress…
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects [Phase 2]
Phase 2 clinical trial investigating how blocking AMPA receptors modulates ketamine's anti-suicidal effects; currently recruiting.
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: Predictors of Relapse in Major Depressive Disorder
A clinical trial is currently recruiting to identify predictors of relapse in Major Depressive Disorder, seeking to understand factors assoc…
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: Neurocardiac Predictors of Treatment Response to RTMS in Depression [NA]
This clinical trial update describes a University of British Columbia study investigating neurocardiac predictors of response to repetitive …
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Impact of Behavioral Activation on Depression and Quality of Life in Patients with Colon Cancer [NA]
A clinical trial is investigating whether Behavioral Activation can improve depression symptoms and quality of life in patients with colorec…
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: MST for Parkinson's Disease [NA]
A clinical trial update for MST therapy in Parkinson's disease and depression shows the study is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Electrical Vestibular Nerve Stimulation (VeNS) As a Treatment for Depression [NA]
The trial evaluating Electrical Vestibular Nerve Stimulation (VeNS) for depression has been completed. The sponsor is Neurovalens Ltd.
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: Association of Beta Blocker Use with Depressive Outcomes
A clinical trial update examining whether use of beta blockers is associated with depressive outcomes in adults with major depressive disord…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Mindfulness Based Stress Reduction and Post-Stroke Cognition [NA]
A Johns Hopkins University-sponsored trial evaluating mindfulness-based stress reduction for post-stroke cognition has completed and posted …
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: Breathing Exercises on Depression in Postmenopausal Women [NA]
This document reports a clinical trial evaluating whether breathing exercises can reduce depressive symptoms in postmenopausal women; the tr…
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: Patient-oriented Randomized Pragmatic Feasibility Trial with RTMS in Depression and Anxiety [NA]
A patient-oriented randomized pragmatic feasibility trial is evaluating repetitive transcranial magnetic stimulation for depression and anxi…
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FDA approval · 2024-12-19FDA Approved: BUPROPION HYDROCHLORIDE XL — Supplemental Application (Oryza pharmaceuticals Inc.)
The FDA approved a supplemental application for Bupropion Hydrochloride XL from Oryza Pharmaceuticals Inc., confirming the extended-release …
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression [NA]
This clinical study from Unity Health Toronto investigates how working memory tasks and reward-related brain markers influence dorsolateral …
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Characterizing the Association Between Preoperative Depressive Symptoms and Opioid Use/Misuse After Surgery
This completed study analyzes whether preoperative depressive symptoms predict opioid use or misuse after surgery.
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: The Effect of Auricular Press Needle on Visual Analogue Scale (VAS) and Short Form (SF-12) Scores in Chronic Pain With Depression Symptoms [NA]
Completed trial evaluating auricular press needle therapy for chronic pain with depressive symptoms, measuring changes in pain via VAS and q…
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FDA approval · 2024-12-17FDA Approved: BUPROPION HYDROCHLORIDE (XL) — Supplemental Application (Vitruvias Therapeutics)
FDA approved a supplemental application for Bupropion Hydrochloride Extended-Release (XL) from Vitruvias Therapeutics under ANDA208652, appr…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Clinical Validation Study for EDIT-B Test: an Aid for Differential Diagnosis of Bipolar Disorder, Based on RNA Editing Blood Biomarkers
Completed clinical validation study for the EDIT-B blood biomarker test designed to differentiate bipolar disorder from major depressive dis…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Nitrous Oxide for the Treatment of Major Depressive Disorder [Phase 2]
Phase 2 trial evaluating nitrous oxide for major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: DTA (Dopaminergic Therapy for Anhedonia) Study [Phase 4]
Phase 4 trial of Dopaminergic Therapy for Anhedonia has completed, with results posted on 2024-12-16.
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Web-based Collaborative Care Intervention Study [NA]
The University of Pittsburgh-sponsored web-based collaborative care intervention trial for cancer-related depression, fatigue, and pain has …
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Effects of a Single-bout of Moderate-intensity Aerobic Exercise on Mood and Mental Health Biomarkers in Adults with Depressive And/or Anxiety Symptoms [NA]
A completed clinical trial evaluated whether a single session of moderate-intensity aerobic exercise impacts mood and mental health biomarke…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Behavioral Activation for the Prevention and Treatment of Depression in Older Adults in a Municipal Context [NA]
This ClinicalTrials.gov entry describes a recruiting study in Sweden evaluating behavioral activation to prevent and treat depression in old…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Collaborative Care Intervention for Chronic Kidney Disease [NA]
The study reports completion of a collaborative care intervention trial for chronic kidney disease, addressing depression in participants su…
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: Collaborative Care Intervention for Cancer Caregivers [NA]
The clinical trial investigating a collaborative care intervention for caregivers of patients with advanced cancer has completed.