Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: SFGT for Persistent Anxiety and Depression [NA]
This document provides a completed clinical trial update for SFGT aimed at persistent anxiety and depressive symptoms. The trial was sponsor…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Internet-delivered Intervention Targeting Residual Cognitive Symptoms After Major Depressive Disorder [NA]
A completed clinical trial evaluating an internet-delivered cognitive remediation intervention for residual cognitive symptoms after major d…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Evaluation of Response to a Course of Repetitive Transcranial Magnetic Stimulation Using Vocal Biomarkers
A clinical trial evaluating response to repetitive transcranial magnetic stimulation in major depressive disorder has been suspended.
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: The Group Risk Reduction Intervention Therapy (GRRIT) Project [NA]
A clinical trial update for the GRRIT Project evaluating a group risk reduction intervention therapy. The study aims to reduce suicidality, …
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Efficacy and Safety of DTMS in Adolescent Major Depressive Disorder [NA]
An ongoing clinical trial is evaluating the efficacy and safety of deep transcranial magnetic stimulation (DTMS) for adolescents with major …
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Prediction of the Response to a Course of Transcranial Magnetic Stimulation (rTMS) Based on Heart Rate Variability
The study investigating whether heart rate variability can predict response to transcranial magnetic stimulation for major depressive disord…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: EMDR Versus Imagery Rescripting for Trauma-Related Intrusions [NA]
A clinical trial comparing EMDR and imagery rescripting for trauma-related intrusions is currently enrolling by invitation; sponsor is Geest…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: Neural Mechanisms of Monoaminergic Engagement in Late-life Depression Treatment Response (NEMO) [Phase 4]
Phase 4 clinical trial update on neural mechanisms of monoaminergic engagement in late-life depression treatment response. Results have been…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: The Impact of Melatonin Lotion on Sleep and Mental Health [NA]
A clinical trial is currently recruiting to evaluate the effects of a melatonin lotion on sleep problems and comorbid depressive and anxiety…
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: Study of Mindfulness-based Group Treatment in Patients With Depression and Anxiety [NA]
Completed clinical trial evaluating mindfulness-based group treatment for patients with depression and anxiety.
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: BEhavioral Health Stratified Treatment (BEST) Study for Youth With Intellectual and/or Developmental Disabilities (IDD) [NA]
A clinical trial update for the BEhavioral Health Stratified Treatment (BEST) Study evaluating interventions for youth with intellectual and…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents [NA]
A clinical trial update for PATH 2, investigating primary care and community-based prevention of mental disorders in adolescents, with the s…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: A Study to Test the Effect of Different Doses of BI 1358894 and Quetiapine in People With Depression [Phase 2]
Phase 2 study evaluating different doses of BI 1358894 in combination with quetiapine for major depressive disorder; the trial has completed…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: RCT of a Brief Video Intervention Targeting Peer Inclusion to Reduce Depression-related Stigma in Adolescents [NA]
A randomized controlled trial evaluated a brief video intervention to reduce depression-related stigma and encourage help-seeking among adol…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Personalized Repetitive Transcranial Magnetic Stimulation Treatment for Major Depressive Episode [NA]
A clinical trial evaluating personalized repetitive transcranial magnetic stimulation for Major depressive episode has reached completion.
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: JoyPop Mobile Mental Health App With Indigenous Youth [NA]
The clinical trial update indicates that the JoyPop mobile mental health app is recruiting Indigenous youth to address emotion regulation, d…
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FDA approval · 2025-03-06FDA Approved: BUPROPION — Supplemental Application (Zydus Pharmaceuticals USA Inc.)
FDA approved Zydus Pharmaceuticals USA Inc.'s supplemental application for Bupropion (ANDA 201567), enabling a generic version of the antide…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: A Pilot Study of Prophylactic Management of Lamotrigine in Pregnant Women
A completed pilot trial evaluating prophylactic management of lamotrigine in pregnant women with bipolar disorder, major depressive disorder…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Role Of Ketamine in Treatment-Resistant Major Depressive Disorder And Its Effect on Suicidality [NA]
Completed clinical trial evaluating ketamine for treatment-resistant major depressive disorder and its effect on suicidality.
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Safety, Tolerability, and Efficacy of Sublingual Microdoses of 5-MeO-DMT for Depression and Anxiety [Phase 1, Phase 2]
Phase 1/2 trial evaluating sublingual microdoses of 5-MeO-DMT for depression and anxiety has completed, reporting safety and tolerability wi…
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FDA approval · 2025-03-05FDA Approved: ESCITALOPRAM — Supplemental Application (SOLCO HEALTHCARE US, LLC)
The FDA granted a supplemental approval for escitalopram (generic) from Solco Healthcare US, LLC under an ANDA.
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Testing the Effectiveness of AI Chatbots to Improve Public Knowledge and Attitudes Towards Depression [NA]
This clinical trial update describes an ongoing study testing AI chatbots to improve public knowledge and attitudes toward depression; the t…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Promoting Active Therapy: Path to Wellness [Phase 2]
Phase 2 clinical trial sponsored by Kansas State University evaluating a behavioral intervention called Promoting Active Therapy: Path to We…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Vibraimage Technology for Detecting Depression in Psychiatric Outpatients
Clinical trial using Vibraimage Technology to detect depression in psychiatric outpatients has completed.
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Outreach to Reduce Depression Disparities [NA]
This clinical trial update reports the completion of a Kaiser Permanente study focused on outreach to reduce disparities in depression care.