Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Equity Using Interventions for Pain and Depression - Pilot Study [NA]
A pilot trial from Indiana University evaluates equity-focused interventions for chronic pain and depression. Results have been posted for t…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Testing a Transdiagnostic TMS Treatment Target [EARLY_Phase 1]
An early-phase Phase 1 trial evaluating a transdiagnostic TMS treatment across multiple psychiatric conditions, including major depressive d…
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CLINICAL_TRIALS withdrawal · 2025-06-11Clinical Trial Update: Evaluating an Online Wellness Intervention for Greek Adolescents [NA]
The clinical trial evaluating an online wellness intervention for Greek adolescents has been withdrawn. The study targeted depressive sympto…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis [NA]
A recruiting clinical trial at the University of Illinois at Chicago is evaluating exercise training as a management approach for major depr…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Adapting BA for Minimally Verbal Autistic Adults [NA]
A Rutgers-sponsored clinical trial is evaluating an adaptation of behavioral activation for minimally verbal adults with autism, with comorb…
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CLINICAL_TRIALS trial_result · 2025-06-10Clinical Trial Update: Antidepressant Effects of TS-161 in Treatment-Resistant Depression [Phase 2]
The Phase 2 study of TS-161 for treatment-resistant depression was terminated, and trial results have been posted.
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CLINICAL_TRIALS trial_result · 2025-06-10Clinical Trial Update: Pilot Study of GLY-LOW Supplementation in Postmenopausal Women With Obesity [EARLY_Phase 1]
An early-phase (Phase 1) pilot trial of GLY-LOW supplementation in postmenopausal women with obesity has completed, according to the clinica…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: A Study to Assess Serotonin Transporter Occupancy of Healthy Adults Using 11C-DASB PET [Phase 1]
A Phase 1 study in healthy adults assessing serotonin transporter occupancy using the PET tracer 11C-DASB.
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Switching Medication and Augmentation Strategies for SSRI-Resistant Adolescent Depression（SMART-I) [Phase 4]
A Phase 4 clinical trial update is evaluating switching medications and augmentation strategies for adolescents with SSRI-resistant major de…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Assessment of Whether Telehealth Family Psychoeducation for Major Depressive Disorder is Doable [NA]
This clinical trial update describes a feasibility assessment to determine whether telehealth-based family psychoeducation for Major Depress…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: (GluEsk) Glutamate and Esketamine [NA]
A completed University of Oxford clinical trial evaluating glutamate and esketamine for depression.
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Engaging Suicidal Patients in Mental Health Treatment [NA]
The University of Pennsylvania completed a clinical trial focused on engaging suicidal and depressed patients in mental health treatment, wi…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Repetitive Transcranial Magnetic Stimulation and Acceptance and Commitment Therapy [NA]
A clinical trial evaluating repetitive transcranial magnetic stimulation combined with Acceptance and Commitment Therapy for chronic pain an…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Aβ Dynamics in LLMD [Phase 4]
A Phase 4 clinical trial evaluating beta-amyloid dynamics in late-life major depressive disorder and Alzheimer's disease is currently recrui…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: A Pilot Study of Synbiotics in Adults With Depressive Symptoms [NA]
A pilot study evaluating a synbiotic formulation in adults with mild-to-moderate depressive symptoms is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: Bright Start Study [NA]
The Bright Start Study, sponsored by Kaiser Permanente, has completed its clinical trial with results posted on 2025-06-06.
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Probiotic Administration for Adolescent Depression [EARLY_Phase 1]
This document reports an early-phase 1 clinical trial investigating probiotic administration for adolescent depression, with recruitment ong…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Effectiveness of mHealth Post-discharge Intervention for Patients With Severe Mental Illness [NA]
This clinical trial update notes that enrollment is ongoing by invitation for a study evaluating a mobile health post-discharge intervention…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Cognitive Rehabilitation for Veterans With MDD-related Cognitive Functioning Deficits [NA]
A clinical trial update indicates a study is recruiting to evaluate cognitive rehabilitation for veterans with cognitive deficits related to…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Spatiotemporal Dynamics of the Human Emotion Network [NA]
A UCSF-led clinical trial is investigating the spatiotemporal dynamics of the human emotion network and is currently enrolling by invitation…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries [NA]
A Boston Medical Center trial is evaluating therapy dog visits for patients hospitalized with traumatic injuries to support recovery and add…
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Low-Income Group Psilocybin Assisted Therapy for Depression [NA]
This clinical trial update reports the completion of a study evaluating psilocybin-assisted therapy for depression in a low-income populatio…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: PET Biomarker Study for Antidepressant Response Prediction in Major Depressive Disorder [NA]
This clinical trial outlines a PET biomarker study aimed at predicting antidepressant response in major depressive disorder. The study is no…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Effects and Cost-effectiveness of e-Meistring - a Guided Internet-delivered Psychological Treatment
This update describes a clinical trial evaluating the effects and cost-effectiveness of e-Meistring, a guided internet-delivered psychologic…
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Assessing Improvements in Mood and Sleep Trial [NA]
A University of Pittsburgh-sponsored clinical trial is assessing improvements in mood and sleep for depression and suicidality, and is curre…