Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosis (MS) [Phase 2]
Phase 2 clinical trial evaluating home-based transcranial direct current stimulation (tDCS) for depression in people with multiple sclerosis…
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for Refractory Anorexia Nervosa With Comorbid Obsessive Compulsive Disorder or Major Depressive Disorder [Phase 1]
A Phase 1 clinical trial evaluating MRI-guided focused ultrasound bilateral capsulotomy for treatment-refractory anorexia nervosa with comor…
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: A Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy [Phase 3]
Phase 3 study comparing seltorexant to quetiapine XR as adjunctive therapy to antidepressants in adults and elderly with major depressive di…
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: A Journey to Balance: Development and Validation of Individualized Life Balance Intervention for Depression [NA]
The document reports the completion of a clinical trial evaluating the development and validation of an individualized Life Balance Interven…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Effectiveness and Cost-effectiveness of Digital Psychological Intervention (EmoEase) in Chinese COPD Patients [NA]
A clinical trial evaluating the effectiveness and cost-effectiveness of a digital psychological intervention (EmoEase) for Chinese patients …
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Modulating Spinal Interoceptive Pathways to Evaluate Their Role and Therapeutic Potential in MDD Symptomatic Domains [Phase 1, Phase 2]
A University of Cincinnati-led clinical trial is evaluating modulation of spinal interoceptive pathways as a treatment strategy for major de…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety
A Region Stockholm-sponsored trial is evaluating physical exercise as an adjunctive treatment for mood and anxiety disorders, with the study…
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: Nurse Telephone Follow-up for Cardiovascular Patients [NA]
This clinical trial update reports the completion of a study evaluating nurse telephone follow-up for cardiovascular patients, with attentio…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Efficacy of Chronotherapeutic Combination for Major Depressive Episode With Insomnia [Phase 3]
Phase 3 clinical trial evaluating the efficacy of a chronotherapy-based combination for major depressive disorder with insomnia; trial statu…
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: Body-Mind-Spirit Action Group on the Well-being [NA]
A completed clinical trial sponsored by Taipei City Hospital evaluating quality of life and depression outcomes.
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: The MOOD Study - External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) for the Treatment of Major Depressive Disorder (MDD) [NA]
This update reports the completed MOOD Study evaluating the eCOT-NS device for major depressive disorder, with trial results posted.
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Use of Virtual Reality as a Tool for Cognitive Remediation in Elderly Depressed Patients [NA]
A clinical trial is planned to evaluate virtual reality as a cognitive remediation tool for elderly patients with major depressive disorder;…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Pramipexole for Anhedonic Depression [Phase 3]
Pramipexole is being studied in a Phase 3 trial for anhedonic depression. The study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Depression, Illness Perception, and Erectile Dysfunction Outcomes
A clinical trial investigating erectile dysfunction, depression, and illness perception is currently enrolling by invitation at Haseki Train…
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: Problem Adaptation Therapy for Mild Cognitive Impairment and Depression [NA]
Completed clinical trial evaluating Problem Adaptation Therapy for Mild Cognitive Impairment with comorbid Depression; results have been pos…
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Autism Genomics Sweden - Genetic Guidance and Information Trial [NA]
A completed clinical trial in Sweden evaluating genetic guidance and information for autism and related neurodevelopmental and mood/anxiety …
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Ketamine-Assisted Mindfulness-Based Cognitive Therapy for Depression: A Pilot Study [Phase 4]
A Phase 4 pilot clinical trial at Ohio State University is evaluating ketamine-assisted mindfulness-based cognitive therapy for major depres…
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Individualizing Incentives for Alcohol in the Severely Mentally Ill [NA]
This clinical trial update reports the completion of a study evaluating individualized incentives to address alcohol use in severely mentall…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Biobank and Brain Health in Bordeaux.
A Bordeaux-based clinical trial is recruiting participants for a biobank study focused on brain health and aging, including cognitive aging …
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Mechanisms of Rumination Change in Adolescent Depression [NA]
A clinical trial update from Ohio State University on mechanisms underlying rumination changes in adolescents with major depressive disorder…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Accelerated TMS for Treatment-Resistant ECT [NA]
A clinical trial is evaluating accelerated transcranial magnetic stimulation for treatment-resistant major depressive disorder and is curren…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Multimodal Identification of Depressive Symptoms in the Elderly
A clinical trial update about a study aimed at multimodal identification of depressive symptoms in the elderly, currently not yet recruiting…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Neuro-affective Response to Light in Depressed Adolescents and Young Adults [NA]
This clinical trial update indicates that the study investigating neuro-affective responses to light in depressed adolescents and young adul…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Development and Feasibility of a Metaverse-based Blended Online Intervention to Prevent Employees' Depression [NA]
The study completed development and feasibility evaluation of a metaverse-based blended online intervention intended to prevent depression a…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Disposition Kinetics of Dolutegravir Among People Living With HIV With Major Depression in Nigeria [Phase 4]
Phase 4 clinical trial update on disposition kinetics of dolutegravir in people living with HIV who have major depression in Nigeria; the st…