Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Efficacy, Safety, and Acceptability of Internet-based Cognitive Behavioral Therapy [NA]
A completed clinical trial evaluating the efficacy, safety, and acceptability of internet-based cognitive behavioral therapy for depression.…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: High-Frequency vs. Theta-Burst TMS for Depression [NA]
A completed clinical trial comparing high-frequency transcranial magnetic stimulation (TMS) with theta-burst TMS for major depressive disord…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Personalized rTMS for Resistant Depression [NA]
A clinical trial update notes that a study of personalized repetitive transcranial magnetic stimulation for treatment-resistant depression h…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Apimostinel + Automated Neurocognitive Training for Depression [Phase 2]
Phase 2 clinical trial update for depression evaluating Apimostinel in combination with Automated Neurocognitive Training; the study is curr…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Acupuncture for Anxiety/Depression in Patients With Breast Cancer [NA]
A clinical trial evaluating acupuncture for anxiety and depression in patients with breast cancer is currently not recruiting.
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FDA approval · 2025-09-24FDA Approved: PAROXETINE — Original Application (Alembic Pharmaceuticals Inc.)
FDA approves Alembic Pharmaceuticals Inc. Paroxetine Original Application for a generic paroxetine product.
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: M-O-M-S on the Bayou: Implementation of an Intervention for Mental Health in Pregnancy [NA]
The study 'M-O-M-S on the Bayou' is currently recruiting to implement an intervention for mental health in pregnancy, focusing on anxiety an…
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CLINICAL_TRIALS withdrawal · 2025-09-24Clinical Trial Update: Noninvasive Transcutaneous Vagal Nerve Stimulation (tcVNS) for Neuromodulating the Conscious State [NA]
The Northwestern University trial on noninvasive transcutaneous vagal nerve stimulation for neuromodulating the conscious state has been wit…
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: Cellular Aging and Neurobiology of Depression Study [NA]
This document notes the completion of a clinical trial investigating cellular aging and neurobiology in major depressive disorder.
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Schema Therapy for Patients With Chronic Treatment Resistant Depression [NA]
A clinical trial is evaluating schema therapy for patients with chronic treatment-resistant depression, and the study is currently recruitin…
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: Depression & Insulin Sensitivity in Adolescents [NA]
Completed study in adolescents examining the relationship between depression and insulin sensitivity in those with Type 2 diabetes, with obe…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: In-patient SCC TMS [NA]
An in-patient transcranial magnetic stimulation trial (SCC TMS) for Major Depressive Disorder is currently recruiting at UCLA.
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Effect of Probiotics "Psychobiotics" on Depression and Metabolic Syndrome in Saudi Arabia [Phase 2, Phase 3]
Phase 2/Phase 3 clinical trial in Saudi Arabia evaluating the effects of probiotic psychobiotics on depression, anxiety disorders, and metab…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Efficacy and Safety of Transcranial Alternating Current Stimulation (tACS) Combined With Stable Medication in Adolescents With Depression: A Randomized, Double-Blind, Controlled Pilot Study [NA]
This document reports a randomized, double-blind, controlled pilot trial assessing whether adding transcranial alternating current stimulati…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Internet-Based Cognitive Behavioral Therapy With Treatment as Usual for Generalized Anxiety Disorder and Major Depressive Disorder in Taiwan (ICBT-TW) [NA]
A clinical trial in Taiwan evaluating internet-based cognitive behavioral therapy in addition to usual care for generalized anxiety disorder…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Evaluation of the PACE/PACENET BHL Clinical Program
Clinical trial update on the PACE/PACENET BHL program indicates ongoing recruitment for studies addressing depression, anxiety disorders, an…
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CLINICAL_TRIALS other · 2025-09-22Clinical Trial Update: Nano-Learning for Improving Compliance Among Older Adults With Sarcopenia [NA]
Clinical trial update for a nano-learning intervention aimed at improving compliance in older adults with sarcopenia; the study is currently…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Extended Reality Behavioral Activation: An Intervention for Major Depressive Disorder [NA]
A completed clinical trial evaluating Extended Reality Behavioral Activation as an intervention for Major Depressive Disorder.
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Effects of Mindfulness or Brain Stimulation Intervention for Late-life Adults in Taiwan Urban and Rural Areas [NA]
This ClinicalTrials.gov entry describes an ongoing study in Taiwan evaluating mindfulness and brain stimulation interventions for late-life …
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Resonant Frequency rTMS: A Novel Approach to Target Circuit Modulation in Major Depressive Disorder [NA]
An ongoing UCLA-sponsored clinical trial is evaluating resonant frequency repetitive transcranial magnetic stimulation as a novel approach t…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Efficacy and Safety of Task-specific, Biomarker-driven, HD-ctACS inTRD. [NA]
Clinical trial update on the efficacy and safety of task-specific, biomarker-driven, HD-ctACS in treatment-resistant depression, sponsored b…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: SUpport From PEeRs to Expand Access Study - Community [NA]
This clinical trial update indicates the University of California, Berkeley–sponsored 'Support From Peers to Expand Access' Community study …
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Prevention of ANxiety and Depression Over Risk Assessment [NA]
A clinical trial update describing a preventive study for anxiety and depression based on risk assessment, currently not yet recruiting.
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CLINICAL_TRIALS other · 2025-09-22Clinical Trial Update: Intermittent Theta Burst Stimulation for MDD [NA]
A clinical trial evaluating intermittent theta burst stimulation for major depressive disorder is currently suspended.
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Effects of Intravenous (IV) Citalopram Hydrochloride During Transcranial Magnetic Stimulation in Major Depressive Disorder (MDD) [EARLY_Phase 1]
An early Phase 1 trial update evaluating intravenous citalopram hydrochloride during transcranial magnetic stimulation in major depressive d…