Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Effect of Esketamine on Perioperative Negative Mood in Patients Undergoing Cardiac Valve Surgery [NA]
A completed clinical trial update evaluating whether esketamine influences perioperative mood in patients undergoing cardiac valve surgery.
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Two Doses of Psilocybin for the Treatment of MDD in Adults With Cancer [Phase 2]
Phase 2 clinical trial evaluating two doses of psilocybin for major depressive disorder in adults with cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Predictors and Process Moderators of EMDR Therapy for Depressive Symptoms
A clinical trial from the University of Turin is investigating predictors and process moderators of EMDR therapy for depressive symptoms, wi…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Characterizing Cognitive Decline in Late Life Depression: The ADNI Depression Project
This update describes the ADNI Depression Project led by the University of Southern California to study cognitive decline in individuals wit…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Ketamine-Enhanced Therapy for Individuals With Alcohol Use Disorder and Depression: A Pilot Study (KET-DUAL) [Phase 1, Phase 2]
A Phase 1/2 pilot trial evaluating ketamine-enhanced therapy for individuals with alcohol use disorder and major depressive disorder; the st…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Equipping Patients Using Interventions for Pain and Depression [NA]
Indiana University is recruiting participants for a clinical trial aimed at interventions for chronic pain and depression, including musculo…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: An Individual-specific Synchrony Signature [NA]
An ongoing clinical trial is investigating an individual-specific synchrony signature for Major Depressive Disorder and is currently recruit…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: The Pregnancy and Postpartum Mental Health Optimization Virtual Intervention Network [NA]
A clinical trial from Women's College Hospital evaluating a virtual intervention network to optimize mental health during pregnancy and post…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Community Based Mental Health Screening and Referral [NA]
A community-based mental health screening and referral trial led by Dr. Jai Kumar Das has completed, focusing on mental health issues such a…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Evaluating the Effectiveness of an Online Cognitive Behavioral Therapy Program for University Students With Depression and/or Anxiety [NA]
This clinical trial update reports on the ongoing evaluation of an online cognitive behavioral therapy program for university students with …
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Families With Pride ("Familias Con Orgullo"). [NA]
A clinical trial update from the University of Miami for a study titled Families With Pride (Familias Con Orgullo) investigating depression …
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: An eHealth Intervention to Increase Depression Treatment Initiation and Adherence Among Veterans Referred for Mental Health Services [NA]
This clinical trial update reports results for an eHealth intervention designed to increase initiation and adherence to depression treatment…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Effect of Immersive Virtual Reality-based Cognitive Remediation in Patients With Mood - or Psychosis Spectrum Disorders [NA]
A completed clinical trial assessing immersive virtual reality–based cognitive remediation for mood- and psychosis-spectrum disorders.
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Accelerated TMS for MDD [NA]
A clinical trial update shows accelerated transcranial magnetic stimulation is being studied for major depressive disorder. The study (NCT07…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Diet and Depression [NA]
A completed clinical trial evaluating the relationship between diet and depression, with additional notes on metabolic-related conditions su…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Empower@Home: Hybrid Effectiveness-Implementation Randomized Controlled Trial (RCT) [NA]
The Empower@Home trial is a hybrid effectiveness-implementation randomized controlled trial for depression, and it is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Empower@Home: Community Implementation for Older Adults With Ambulatory Disabilities [NA]
Clinical trial update for Empower@Home, a community implementation study for older adults with ambulatory disabilities addressing depression…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Internet-Delivered Psychological Treatment for Cancer Survivors [NA]
A Karolinska Institutet-led clinical trial evaluating internet-delivered psychological treatment for cancer survivors with anxiety and depre…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Therapy and Tech Study [NA]
A trial update noting a therapy and technology study sponsored by UC Irvine for generalized anxiety disorder and major depressive disorder; …
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Dose-Optimized and Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression [NA]
A completed clinical trial evaluating dose-optimized and spaced transcranial direct current stimulation for treatment-resistant depression a…
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FDA approval · 2025-11-20FDA Approved: SERTRALINE HYDROCHLORIDE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for sertraline hydrochloride manufactured by Aurobindo Pharma Limited. This approval covers a generi…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: The Friendship Bench Plus Trial [NA]
Clinical trial update indicates that The Friendship Bench Plus Trial is currently recruiting for Major Depressive Disorder and severe depres…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Structured Group Therapy in Reducing Depression and Anxiety in Pakistan [NA]
A clinical trial update from the Pakistan Association of Cognitive Therapists on structured group therapy aimed at reducing depression and a…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in the Prevention of Comorbidity Among Junior Middle School Students [NA]
A clinical trial update describes a study of a comprehensive physical education-based intervention to prevent comorbidity in junior middle s…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: A Study of the Effectiveness and Safety of JS1-1-01 in Patients With Moderate to Severe Depression [Phase 2]
This Phase 2 clinical trial update reports the effectiveness and safety of JS1-1-01 in patients with moderate to severe depression, and the …