Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: rTMS in Alleviating Pain and Co-Morbid Symptoms in Gulf War Veterans Illness (GWVI) [NA]
A completed clinical trial evaluating repetitive transcranial magnetic stimulation (rTMS) for pain and co-morbid symptoms in Gulf War Illnes…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Teachers Leading the Front Lines - Adolescent [NA]
A University of North Carolina study is recruiting adolescents to address behavioral and emotional problems, including depression and anxiet…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms [NA]
Johns Hopkins University is conducting a study comparing Cognitive Behavioral Therapy for Insomnia (CBT-I) and MBTI for insomnia and PTSD-re…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Impact of Nut Consumption on Mental Health in Young Adults [NA]
A clinical trial update announcing ongoing recruitment to study the effects of nut consumption on mental health in young adults, focusing on…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: The Effects of Chiropractic on Adults With Depression [NA]
Clinical trial evaluating the effects of chiropractic on adults with depression; currently not recruiting.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Neuroscience of Psychotherapy for Depression [NA]
This entry notes an ongoing clinical trial investigating the neuroscience behind psychotherapy for depression, currently recruiting particip…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Promoting Positive Emotions in Adolescents Using Positive Events Training: An Indicated Approach [NA]
A KU Leuven clinical trial is evaluating Positive Events Training to promote positive emotions in adolescents with emotional distress and an…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity [NA]
This clinical trial update notes ongoing recruitment for a study validating an autonomous internet-based delivery of empirically supported c…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Trial of a Positive Psychology Intervention for Older Adults (RESET) [NA]
A University of Michigan–led trial (RESET) is evaluating a positive psychology intervention for older adults with depressive symptoms and an…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia [NA]
This clinical trial update describes a study evaluating bilateral prefrontal and insular transcranial magnetic stimulation for depression in…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Feasibility Trial of Exercise as a Priming Strategy for rTMS Treatment in Difficult-to-Treat Depression [NA]
ClinicalTrials.gov update describing a feasibility study evaluating whether exercise can prime response to repetitive transcranial magnetic …
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Meditation Accelerated Brain Stimulation for Depression [NA]
A clinical trial update describes a study on meditation-accelerated brain stimulation for depression; the study is currently active but not …
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Attenuating DEPression With Internet CBT to Slow Cognitive Decline in Older ICU Survivors(ADEPT-ICU) [NA]
A clinical trial (ADEPT-ICU) is evaluating internet-delivered cognitive behavioral therapy to treat depression and slow cognitive decline in…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Comparing the Efficacy of fMRI-Guided vs. Standard iTBS in Treating Depression [NA]
A clinical trial comparing fMRI-guided intermittent theta-burst stimulation (iTBS) versus standard iTBS for depression, currently recruiting…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: fMRI Neurofeedback With Matter Neuroscience App [NA]
Stanford University is conducting a clinical trial of fMRI neurofeedback using the Matter Neuroscience app to treat major depressive disorde…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Remote Evaluation and Alerting for Collaborative Health (REACH) in Depression [NA]
A clinical trial update announces the REACH study for depression, sponsored by Dartmouth-Hitchcock Medical Center, currently not yet recruit…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Major Depressive Disorder [NA]
A clinical trial update indicates a study evaluating closed-loop transcranial alternating current stimulation for major depressive disorder …
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Change in Social Media Use and Well-being Among College Students Receiving a Two-week Exercise or Mindfulness Intervention [NA]
A Johns Hopkins trial is recruiting college students to evaluate how a two-week exercise or mindfulness program affects social media use and…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: A Clinical Study to Evaluate of Single and Multiple Oral Doses of GM-1020 in Patients With MDD [Phase 2]
Phase 2 trial of GM-1020 for major depressive disorder has completed. The study evaluated single and multiple oral doses.
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Exploring the Effects of Corticosteroids on the Human Hippocampus [Phase 4]
Phase 4 clinical trial evaluating the effects of hydrocortisone on the hippocampus in depression; results have been completed and posted.
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease [Phase 2, Phase 3]
This report updates on a completed Phase 2/3 clinical trial evaluating the initial prescription of ketamine and milnacipran for depression i…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: OMT as an Adjunctive Treatment in MDD [NA]
This entry reports the completion of a clinical trial evaluating OMT as an adjunctive treatment for Major Depressive Disorder.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: An Empirical Study on the Mechanisms of Biopsychosocial Functional Improvement in Patients With Major Depressive Disorder Through Nature-Based Tourism Activities [NA]
This clinical trial update describes an ongoing empirical study examining how biopsychosocial functional improvements in patients with Major…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Depressive Symptoms, Cognitive Impairment, and Outcomes in Hospitalized Chronic Heart Failure Patients
An ongoing clinical trial sponsored by the Lithuanian University of Health Sciences is evaluating depressive symptoms, cognitive impairment,…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Right-sided 1-Hz Repetitive Transcranial Magnetic Stimulation (rTMS) Versus Left-sided Intermittent Theta Burst Stimulation (iTBS) in Patients With Depression [Phase 4]
This Phase 4 clinical trial compares right-sided 1-Hz repetitive transcranial magnetic stimulation with left-sided intermittent theta burst …