Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Adapted Visual Safety Plan for Autistic Youth (VSP-AY) to Address Self-harm, Suicidal Ideation, and Suicide Behaviors [NA]
Clinical trial update describes the Adapted Visual Safety Plan for Autistic Youth (VSP-AY) aimed at addressing self-harm, suicidal ideation,…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Allogeneic Human Mesenchymal Stem Cell Infusion vs Placebo in Alcohol Use Disorder and Major Depression. [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial comparing allogeneic mesenchymal stem cell infusion to placebo in adults with major depressive disorder…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Physical Therapy for Depression Quality of Life (Pilot Study Protocol) [NA]
A pilot study protocol evaluating physical therapy to improve quality of life for adults with major depressive disorder; sponsor is Universi…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Effect of Family-Based Prevention on Children of Depressed Parents [Phase 1]
A Phase 1 clinical trial evaluated a family-based prevention program for children of depressed parents to assess safety and feasibility. The…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety Study [NA]
This clinical trial update reports a home-based feasibility and safety study of spaced transcranial direct current stimulation for treatment…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care [Phase 3]
Phase 3 clinical trial evaluating home-based telehealth-delivered Behavioral Activation therapy. It aims to improve functioning in patients …
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Personalized Ultrasonic Brain Stimulation for Depression (R61) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating personalized ultrasonic brain stimulation for major depressive disorder, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Effects of a 10-Week Zumba Program on Anxiety and Depression in Adults [NA]
This clinical trial reports the outcomes of a 10-week Zumba program on anxiety and depression in adults.
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Integrating Treatment for Mental Disorders in Methadone Clinics in Ukraine [NA]
The study aims to integrate treatment for mental disorders, including depression and opioid use disorder, within methadone clinics in Ukrain…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Neurobiological and Genomic Predictors of Relapse in Depression
A recruiting clinical study examining neurobiological and genomic predictors of relapse in major depressive disorder, with healthy volunteer…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: A Clinical Study Evaluating the Efficacy and Safety of CreNeuriS CNS Herbal Nutrition Capsules for Participants With Mild Depressive Disorder Comorbid With Anxiety Disorder [NA]
A clinical study evaluating the efficacy and safety of CreNeuriS CNS Herbal Nutrition Capsules for individuals with mild depressive disorder…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: An Examination of the Performance of QbMobile in Differential Diagnosis Associated With ADHD Symptoms
This clinical trial update reviews the performance of QbMobile in aiding differential diagnosis for ADHD symptoms across multiple psychiatri…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Peer-Supported E-Health Intervention for College Student Weight Management and Mental Health [NA]
A completed clinical trial evaluated a peer-supported e-health intervention for weight management and mental health among college students.
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Impact of Ketamine On Depressive Symptoms In Patients Undergoing Lumbo-peritoneal Shunt Insertion [Phase 4]
Phase 4 study evaluating ketamine for depressive symptoms in patients undergoing lumbo-peritoneal shunt insertion has completed.
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: The PATHway Study: Primary Care Based Depression Prevention in Adolescents [NA]
The PATHway Study is a primary care-based program aimed at preventing depression in adolescents; the trial is currently active but not recru…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Problem-Solving Therapy for Cancer Caregivers in Outpatient Palliative Care [NA]
This entry reports the completion of a clinical trial evaluating problem-solving therapy for caregivers of cancer patients in outpatient pal…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Text -Based Depression Screening Among Cancer Survivors [NA]
A recruiting clinical trial evaluating a text-based approach to screen for depression among cancer survivors to identify depressive symptoms…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Individualized Targeting and Neuromodulation of Late-Life Depression [NA]
Clinical trial update on individualized targeting and neuromodulation for late-life depression (major depressive disorder), sponsored by the…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Machine Learning-based Classification of Symptom Clusters and Online CBT [NA]
A Wuhan Mental Health Centre study tests machine learning classification of depression and anxiety symptom clusters and online cognitive-beh…
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FDA approval · 2026-01-07FDA Approved: PROTRIPTYLINE HYDROCHLORIDE — Supplemental Application (Epic Pharma, LLC)
FDA approved the supplemental application for Protriptyline Hydrochloride from Epic Pharma, LLC, authorizing the continued marketing of the …
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression [Phase 2]
Phase 2 trial evaluating BHV-7000 as monotherapy for Major depressive disorder has completed, with efficacy and safety results reported in t…
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FDA approval · 2026-01-07FDA Approved: QUETIAPINE — Supplemental Application (Accord Healthcare Inc.)
The FDA approved Accord Healthcare Inc.'s supplemental application for quetiapine (generic), indicating approval of a modification to an alr…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Well-being Training for Adolescent Depressive Symptoms (TeenWell Study) [NA]
This entry describes a clinical trial investigating well-being training to address depressive symptoms in adolescents. Recruitment is ongoin…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Multiple Ascending Dose Study of NH102 in Healthy Subjects [Phase 1]
Phase 1 multiple ascending dose study of NH102 in healthy subjects has completed, with depression listed as the condition.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Subanesthetic Esketamine in Modified ECT for Severe Depression in Adolescents: Clinical and Mechanistic Study [EARLY_Phase 1]
An early-phase study is evaluating subanesthetic esketamine as an adjunct to modified electroconvulsive therapy for severe depression in ado…