Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Validation of the French Version of the Edinburgh Postnatal Depression Scale (EPDS) Postnatally in the Father [NA]
This clinical trial validates a French version of the Edinburgh Postnatal Depression Scale for use in fathers after birth and is currently r…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons [NA]
A clinical trial evaluating the effectiveness, implementation, and cost of Cognitive Processing Therapy for prisoners with PTSD, including c…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Self-Affirmation Intervention After Mastectomy [NA]
A self-affirmation intervention trial for patients after mastectomy due to breast cancer is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Intervention Effect of High Definition Transcranial Alternating Current Stimulation (HD-tACS) on Depressive Disorder [NA]
A completed clinical trial evaluated the effect of high-definition transcranial alternating current stimulation (HD-tACS) on depressive diso…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Psilocybin for Treatment-Resistant Depression [Phase 2]
Phase 2 clinical trial update on psilocybin for treatment-resistant major depressive disorder; the study is currently active but not recruit…
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CLINICAL_TRIALS withdrawal · 2026-01-21Clinical Trial Update: Long-term Potentiation Disruption Underlying Cognitive Impairment in ECT [EARLY_Phase 1]
An EARLY Phase 1 clinical trial investigating long-term potentiation disruption underlying cognitive impairment in electroconvulsive therapy…
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FDA approval · 2026-01-20FDA Approved: SERTRALINE HYDROCHLORIDE — Original Application (Dr. Reddy's Laboratories Inc.)
FDA-approved original application for sertraline hydrochloride generic (Dr. Reddy's Laboratories) for multiple indications.
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FDA approval · 2026-01-20FDA Approved: SERTRALINE HCL — Original Application (Biocon Pharma Inc.)
FDA approved Biocon Pharma Inc.'s sertraline hydrochloride generic (SERTRALINE HCL) under ANDA218342, expanding access to the generic formul…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: Probiotics Regulate Intestinal Health and Alleviate Anxiety [NA]
A completed clinical trial sponsored by Wecare Probiotics evaluated whether a probiotic product can regulate intestinal health and alleviate…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study of ABX-002 for the Adjunctive Treatment of Depressive Episodes Associated With Bipolar Disorder in Adults [Phase 2]
A Phase 2 clinical trial update for ABX-002 as an adjunctive treatment for depressive episodes in adults with bipolar disorder, currently re…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: Online Cognitive Behavioral Therapy (CBT) for Stress Disorders in Health Workers Involved in the Care of Patients During the Covid-19 Epidemic [NA]
A completed clinical trial evaluated online cognitive behavioral therapy to prevent sleep disorders, PTSD, and depression in health workers …
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: DBS for Depression [Phase 1]
A Phase 1 clinical trial sponsored by Northwell Health evaluating deep brain stimulation for treatment-resistant depression is currently rec…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: PCS in Severe Treatment Resistant Depression [NA]
A clinical trial evaluating PCS for severe treatment-resistant depression is currently recruiting at the University of Minnesota.
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY) [Phase 2]
ABX-002 is being studied as an adjunctive treatment for adults with major depressive disorder in the AMPLIFY trial. The Phase 2 study is cur…
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EMA approval · 2026-01-19EMA Authorised: Brintellix (vortioxetine) — H. Lundbeck A/S
The European Medicines Agency authorised Brintellix (vortioxetine) by H. Lundbeck A/S for major depressive disorder.
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Study of the Effectiveness of Valbenazine on Patient- and Clinician-Reported Outcomes in Participants With Tardive Dyskinesia [Phase 4]
Phase 4 study evaluating valbenazine for tardive dyskinesia in participants with schizophrenia, schizoaffective disorder, bipolar disorder, …
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Reducing Suicide Risk in Older Veterans Using Problem Solving Therapy [NA]
This clinical trial evaluating problem solving therapy to reduce suicide risk in older veterans has been terminated.
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: SOVA Ambassadors Community Setting [NA]
University of Pittsburgh sponsored a trial for major depressive disorder that was terminated, with results posted on 2026-01-16.
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Salivary Oxytocin as a Biomarker of Psychedelic Treatment
A University of Geneva-led trial is investigating whether salivary oxytocin can serve as a biomarker for psychedelic-assisted treatment in m…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Cross-sectoral Collaboration in Multidisciplinary Treatment of Trauma-affected Refugees [NA]
Completed clinical trial evaluating cross-sectoral, multidisciplinary treatment for trauma-affected refugees, with outcomes related to post-…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: HIV-Mental Illness Stigma Reduction and Outcomes in Malawi [NA]
A Malawi-based study sponsored by the University of Pennsylvania is evaluating HIV and mental illness stigma and related outcomes, with enro…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Study on Treatment Mechanisms and Efficacy Prediction of Individualized Transcranial Magnetic Stimulation in Adults With Irritable Bowel Syndrome Using Multimodal MRI and High-Throughput Sequencing [NA]
This clinical trial update describes an enrolling-by-invitation study evaluating individualized transcranial magnetic stimulation for irrita…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Integrated Suicide & Trauma Therapy for Suicide Risk [NA]
A clinical trial recruiting to test an integrated suicide and trauma therapy designed to reduce suicide risk in individuals with trauma expo…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: The WeACT Program for Family Caregivers of People Living With Dementia [NA]
The WeACT Program is a clinical trial to support family caregivers of people living with dementia, with recruitment not yet started.
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FDA approval · 2026-01-15FDA Approved: FLUOXETINE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for a fluoxetine generic product manufactured by Aurobindo Pharma Limited.