Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Evaluation of Clonazepam and Paroxetine for Panic Disorder With Depression [Phase 4]
Phase 4 clinical trial update reporting completion of a study evaluating clonazepam and paroxetine for panic disorder with depression.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Effects of Drugs on Cerebral Blood Flow in Patients With Mood Disorders
A completed National Institute of Mental Health–sponsored trial examined how certain drugs affect cerebral blood flow in people with mood di…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Effects of Sex Hormones on Circadian Rhythm in Men and Women
A completed clinical trial from the National Institute of Mental Health evaluating how sex hormones affect circadian rhythm in men and women…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Study of the Psychological Development of Children of Parents With and Without Affective Disorders
This completed clinical trial, sponsored by the National Institute of Mental Health, studied the psychological development of children of pa…
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CLINICAL_TRIALS research · 2008-03-04Clinical Trial Update: Study of the Hypothalmic-Pituitary-Adrenal (HPA) Axis and Its Role in Major Depression
This clinical trial update from the National Institute of Mental Health examines the role of the hypothalamic-pituitary-adrenal axis in majo…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Use of Bone Biopsy to Better Understand the Causes of Decreased Bone Mineral Density in Depression
This completed clinical trial used bone biopsies to investigate the causes of decreased bone mineral density in individuals with depression,…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Platelet Function in Patients Treated With SSRI and Non-SSRI Antidepressants
A completed clinical trial update examining platelet function in patients treated with SSRI antidepressants compared with non-SSRI antidepre…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Dynamics of Leptin and Endocrine Function
A completed clinical trial examining the relationship between leptin dynamics and endocrine function in healthy individuals and in individua…
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CLINICAL_TRIALS research · 2008-03-03Clinical Trial Update: Routine Plasma Level Determination to Compare Actual vs Expected Plasma Levels at Psychiatric Inpatient Admission
Clinical trial update reporting the completion of a study that compares measured plasma drug levels to expected concentrations in psychiatri…
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FDA approval · 2008-02-29FDA Approved: PRISTIQ EXTENDED-RELEASE — Original Application (Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.)
FDA approved Pristiq Extended-Release (desvenlafaxine succinate) as an original NDA for the treatment of major depressive disorder; Wyeth Ph…
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CLINICAL_TRIALS trial_result · 2008-02-26Clinical Trial Update: Narrative Exposure Therapy Versus Group Interpersonal Psychotherapy [Phase 2]
Phase 2 trial comparing Narrative Exposure Therapy with Group Interpersonal Psychotherapy for post-traumatic stress disorder and depression …
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CLINICAL_TRIALS trial_result · 2008-02-21Clinical Trial Update: Effectiveness Study of Vilazodone to Treat Depression and to Discover Genetic Markers Associated With Response [Phase 3]
A completed Phase 3 study evaluating the effectiveness of vilazodone for major depressive disorder and exploring genetic markers associated …
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FDA approval · 2008-02-20FDA Approved: IMIPRAMINE HYDROCHLORIDE — Supplemental Application (Strides Pharma Science Limited)
The FDA approved a supplemental application for imipramine hydrochloride (generic) from Strides Pharma Science Limited, authorizing a modifi…
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FDA approval · 2008-02-20FDA Approved: IMIPRAMINE HYDROCHLORIDE — Supplemental Application (Strides Pharma Science Limited)
FDA approved a supplemental application for imipramine hydrochloride from Strides Pharma Science Limited. This is a supplemental approval fo…
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CLINICAL_TRIALS trial_result · 2008-02-20Clinical Trial Update: Omega-3 Fatty Acids for Major Depressive Disorder During Pregnancy [NA]
A clinical trial evaluating omega-3 fatty acids for major depressive disorder during pregnancy has completed. Sponsored by Taiwan's National…
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FDA approval · 2008-02-14FDA Approved: FLUOXETINE — Supplemental Application (Chartwell Governmental & Specialty RX, LLC)
FDA approved a supplemental application for fluoxetine from Chartwell Governmental & Specialty RX, LLC.
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FDA label_change · 2008-02-13FDA Approved: EMSAM — Supplemental Application (Viatris Specialty LLC)
The FDA approved a supplemental application for EMSAM (selegiline transdermal patch) from Viatris Specialty LLC. This action updates the pro…
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FDA label_change · 2008-02-07FDA Approved: EFFEXOR XR — Supplemental Application (Viatris Specialty LLC)
The FDA approved a supplemental application for Effexor XR (venlafaxine hydrochloride) submitted by Viatris Specialty LLC.
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CLINICAL_TRIALS research · 2008-02-06Clinical Trial Update: Screening Questionnaire for Depression
This entry provides an update on a clinical trial involving a screening questionnaire for depression, conducted by Sheba Medical Center. The…
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FDA approval · 2008-02-05FDA Approved: PAROXETINE — Supplemental Application (Apotex Corp.)
FDA approved a supplemental application for Apotex Corp. to market a generic paroxetine hydrochloride product (PAROXETINE HYDROCHLORIDE).
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CLINICAL_TRIALS trial_result · 2008-01-31Clinical Trial Update: Medical and Psychiatric Co-Morbidity Among Treatment Resistant Patients With Major Depression Disorder
A completed clinical trial investigating medical and psychiatric comorbidity among treatment-resistant patients with major depressive disord…
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FDA approval · 2008-01-31FDA Approved: FLUOXETINE — Original Application (QUALLENT PHARMACEUTICALS HEALTH LLC)
FDA approved the original application for a generic fluoxetine hydrochloride product from Quallent Pharmaceuticals Health LLC.
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FDA label_change · 2008-01-30FDA Approved: EFFEXOR XR — Supplemental Application (Viatris Specialty LLC)
The FDA approved a supplemental application for Effexor XR (venlafaxine hydrochloride) from Viatris Specialty LLC, updating the product labe…
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CLINICAL_TRIALS withdrawal · 2008-01-29Clinical Trial Update: The Effectiveness of Idazoxan in Treating TRD [Phase 3]
A Phase 3 trial evaluating Idazoxan for treatment-resistant depression has been withdrawn by the sponsor.
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CLINICAL_TRIALS trial_result · 2008-01-25Clinical Trial Update: PUFA Augmentation in Treatment of Major Depression [Phase 3]
A Phase 3 study evaluating polyunsaturated fatty acid (PUFA) augmentation for major depressive disorder has completed.