Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experience of Intimate Partner Violence [NA]
A clinical trial update for MOSAIC, a study focused on pregnant women and mothers with experience of intimate partner violence, currently ac…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Parent Encouragement And Coaching of Happiness in Youth [NA]
This clinical trial, sponsored by the University of Pittsburgh, evaluates a parent-focused program to improve happiness in youth with depres…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Effect of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Severe Depression [NA]
Clinical trial update on whether esketamine reduces perioperative negative emotions in breast cancer surgery patients with severe depression…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Accelerated vs. Conventional Theta Burst Stimulation for Late-life Depression [NA]
A clinical trial is evaluating accelerated versus conventional theta burst stimulation for late-life depression and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Parenting Young Children Study [NA]
A completed clinical trial from the University of Oregon evaluating parenting interventions for families affected by opioid misuse and relat…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: GLP-1 Medicines and Mental Health Changes [NA]
A completed UC San Diego‑sponsored clinical trial evaluated GLP-1 medicines and their effects on mental health in people with obesity and de…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Psychiatric Genotype/Phenotype Project Repository
Clinical trial update from Vanderbilt University describing a psychiatric genotype/phenotype project repository. The study is currently enro…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Digital Cognitive Behavioral Therapy for Chinese Adolescents With Depressive Symptoms（CADS-D ) [NA]
A clinical trial is evaluating a digital cognitive behavioral therapy program (CADS-D) for depressive symptoms in Chinese adolescents, and t…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: NQ Square TMS for MDD 1Dx3S Adults Multi-site Sham-controlled Protocol [NA]
This clinical trial update reports an ongoing sham-controlled study evaluating NQ Square transcranial magnetic stimulation for adults with m…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: To Evaluate the Safety, Tolerability, Pharmacokinetic Characteristics and Food Effects of LY03021 in Healthy Chinese Subjects [Phase 1]
Phase 1 clinical trial assessing safety, tolerability, pharmacokinetics, and food effects of LY03021 in healthy Chinese subjects, with Major…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Effect of Esketamine on Perioperative Negative Emotions in Patients Undergoing Breast Cancer Surgery [NA]
This clinical trial is evaluating whether esketamine reduces perioperative negative emotions in patients undergoing breast cancer surgery an…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Neurocircuitry Mechanisms and Efficacy of Lumateperone as Adjunctive Therapy for Major Depressive Disorder and History of Early Life Abuse [Phase 4]
Clinical trial update on lumateperone as adjunctive therapy for major depressive disorder in patients with early life trauma.
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: The Effectiveness and Efficacy of an Online Cognitive Behavioral Psychotherapeutic Program [NA]
An ongoing clinical trial evaluating the effectiveness and efficacy of an online cognitive behavioral therapy program for depression and anx…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Testing Feasibility of Care Coordination and Motivational Interviewing for Women With a Recent Preterm Birth [NA]
Terminated clinical trial evaluating care coordination and motivational interviewing for women with a recent preterm birth; results have bee…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Factorial Optimization Trial to Test Effects of Coping Intervention Components [NA]
This clinical trial update describes an active but not recruiting factorial study from Arizona State University to evaluate the effects of c…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD) [Phase 1, Phase 2]
The STAR-AD study, a Phase 1/Phase 2 trial exploring sequenced treatment alternatives for adolescent depression, is currently recruiting and…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: A Text Messaging Intervention to Reduce Perinatal Depression Risk [NA]
A completed clinical trial evaluated a text messaging intervention aimed at reducing the risk of perinatal depression, focusing on major dep…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: The Role of Social Determinants in Cardiovascular Health and Vascular Function [NA]
A completed Baylor Research Institute clinical trial examined how social determinants of health influence cardiovascular health and vascular…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: A Novel Cognitive Remediation Intervention Targeting Poor Decision-making and Depression in Veterans at High Risk for Suicide: A Safe, Telehealth Approach During the COVID-19 Pandemic [NA]
Completed clinical trial evaluating a telehealth cognitive remediation intervention to address poor decision-making and depression in vetera…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: The Study of Internet-delivered, Transdiagnostic Treatments for Anxiety and Depression [NA]
The completed study evaluated internet-delivered, transdiagnostic treatments for anxiety and depression. It was sponsored by Stockholm Unive…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Identity-Based Transdiagnostic Therapy for Young People With Anxiety and Depression [NA]
Clinical trial update on identity-based transdiagnostic therapy for anxiety and depression in young people; currently recruiting.
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CLINICAL_TRIALS other · 2026-01-26Clinical Trial Update: Omega-3 Fatty Acids, Inflammation, Gut Microbiota in Youth With Depression [NA]
A clinical trial is evaluating omega-3 fatty acids' effects on inflammation and gut microbiota in youths with ADHD and depression, and the s…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Home-Based Transcranial Direct Current Stimulation In Major Depressive Disorder (HOME) [NA]
A clinical trial update for home-based transcranial direct current stimulation in major depressive disorder, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Amplitude Titration to Improve ECT Clinical Outcomes [NA]
This clinical trial update notes that the University of New Mexico is conducting a study on amplitude titration to improve electroconvulsive…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Tianeptine for Treatment Resistant Depression [Phase 4]
Phase 4 trial update for tianeptine in treatment-resistant depression was terminated, with results posted in January 2026.