Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Modular Intervention for Depression Study [NA]
The clinical trial studying a modular intervention for major depressive disorder is listed as not yet recruiting. It is sponsored by Pontifi…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Effectiveness of Integrated Network for Student Psychosocial Intervention, Resilience, and Education (INSPIRE) on Mental Health Outcomes Among Indonesian Adolescents in Bandung [NA]
This clinical trial update describes the INSPIRE program, evaluating a school-based psychosocial intervention to improve mental health outco…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Expressive Writing on Minority Stressors Among Sexual Minority Veterans [NA]
This is a registered clinical trial evaluating expressive writing to address minority stressors in sexual minority veterans, focusing on dep…
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FDA approval · 2026-01-30FDA Approved: OLANZAPINE AND FLUOXETINE — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
The FDA approved a supplemental application for the olanzapine and fluoxetine combination, expanding/adjusting its labeling under Teva's ove…
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FDA approval · 2026-01-30FDA Approved: OLANZAPINE AND FLUOXETINE — Supplemental Application (Par Health USA, LLC)
FDA approved a supplemental application for the olanzapine and fluoxetine combination (olanzapine + fluoxetine) submitted by Par Health USA,…
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FDA approval · 2026-01-30FDA Approved: VENLAFAXINE HYDROCHLORIDE — Supplemental Application (Marlex Pharmaceuticals, Inc.)
FDA approved a supplemental application for venlafaxine hydrochloride (ANDA201272) from Marlex Pharmaceuticals, Inc., authorizing continued …
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Psilocybin to Treat Depression in Spinal Cord Injury [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating psilocybin for depression in individuals with spinal cord injury is listed as not yet recruiting. The st…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Internet-Based Group CBT for Anxiety and Depression Among International Students [NA]
An update on a clinical trial testing internet-based group cognitive-behavioral therapy for anxiety and depression in international students…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Effects of EMDR on Psychological Symptoms and EEG Findings in Trauma-Exposed Individuals [NA]
A clinical trial update describing a study on EMDR therapy’s effects on psychological symptoms and EEG results in trauma-exposed individuals…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Promoting Resilience in Stroke Survivor-carepartner Dyads (ReStoreD) [NA]
An active, not-recruiting clinical trial from the University of Utah called ReStoreD, investigating resilience-promoting interventions for s…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Real-world Clinical Response to Trazodone in Italy, Poland, and Romania
A real-world clinical trial is recruiting to assess trazodone's clinical response in adults with major depressive disorder and cognitive dis…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Association Analysis of Depression and Asthma
An observational clinical trial in Shanghai is planned to analyze the association between depression and asthma. The study is not yet recrui…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Biomarkers of Depression and Treatment Response [NA]
A clinical trial exploring biomarkers of depression and treatment response, currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experience of Intimate Partner Violence (MOSAIC Plus) Open Trial [NA]
Completed open trial (MOSAIC Plus) evaluating an intervention for pregnant women and mothers with exposure to intimate partner violence and …
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Occupational Therapy for Mental Health and Engagement in Neurorehabilitation [NA]
An ongoing ClinicalTrials.gov trial at Colorado State University is evaluating occupational therapy to support mental health and engagement …
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Effects of a Black Rice Extract and Anthocyanidin Metabolites on the Synthesis and Release of BDNF in Healthy Subjects [NA]
This clinical trial investigates whether a black rice extract and its anthocyanidin metabolites affect the synthesis and release of brain-de…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Brain STimulation for ANxiety and Depression in Youth [NA]
An ongoing clinical trial at the University of Calgary is evaluating brain stimulation for anxiety disorders and depression in youth and is …
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Depression Prevention in Older Spousally-bereaved Adults [NA]
A completed clinical trial assessing depression prevention in older adults who recently experienced spousal bereavement; results have been p…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Open-Label Safety Study of AXS-05 in Subjects With TRD (EVOLVE) [Phase 2]
An open-label Phase 2 safety study of AXS-05 in treatment-resistant depression and major depressive disorder was terminated, with results po…
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FDA approval · 2026-01-28FDA Approved: SERTRALINE HCL — Original Application (Amneal Pharmaceuticals NY LLC)
FDA approves Amneal's generic sertraline hydrochloride tablet via an original ANDA. This decision enables generic competition for sertraline…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Dopaminergic Therapy for Anhedonia - 2 [Phase 4]
Phase 4 clinical trial conducted by Emory University is evaluating a dopaminergic therapy for anhedonia and depression, and is currently rec…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Pilot Testing a Virtual Mindfulness-Based Intervention to Improve Veterans' Health [NA]
A pilot trial evaluated a virtual mindfulness-based intervention to improve health outcomes in veterans with depression, with results posted…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Effect of Continuous Intraoperative Esketamine Infusion on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Mild-to-Severe Depression [NA]
This clinical trial investigates whether continuous intraoperative esketamine infusion can reduce perioperative negative emotions in patient…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Home-Based tDCS for Depression in BPD [NA]
A clinical trial evaluating home-based transcranial direct current stimulation (tDCS) for depression in individuals with Borderline Personal…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Brief Culturally Adapted Behavioral Activation Therapy for Adults With Depression in Rural Indonesian Primary Care: A Type-2 Hybrid Effectiveness-Implementation Trial [NA]
This clinical trial protocol describes a Type-2 Hybrid effectiveness-implementation study evaluating Brief Culturally Adapted Behavioral Act…