Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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FDA approval · 2011-08-12FDA Approved: CELEXA — Supplemental Application (Allergan, Inc.)
FDA approved a supplemental application for Celexa (citalopram) filed by Allergan, Inc.
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CLINICAL_TRIALS trial_result · 2011-08-11Clinical Trial Update: Short-term Study of Combination Treatment of Escitalopram and Gaboxadol in Major Depressive Disorder [Phase 2]
Phase 2 study of short-term combination therapy with escitalopram and gaboxadol for major depressive disorder completed; results posted.
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CLINICAL_TRIALS trial_result · 2011-08-09Clinical Trial Update: Prevention of Depression in HIV/HCV Co-infected Substance Abuse Patients [NA]
This clinical trial update concerns a study aimed at preventing depression in patients co-infected with HIV and Hepatitis C who have substan…
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FDA approval · 2011-08-08FDA Approved: BUPROPION HYDROCHLORIDE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for bupropion hydrochloride from Aurobindo Pharma Limited, allowing the generic product to be market…
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CLINICAL_TRIALS trial_result · 2011-08-05Clinical Trial Update: Cognitive Behavioral Therapy for Early-Onset Depression [NA]
This document provides an update on a completed clinical trial evaluating cognitive behavioral therapy for early-onset major depressive diso…
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CLINICAL_TRIALS trial_result · 2011-08-04Clinical Trial Update: Bone Mineral Content and Bone Metabolism in Adolescents on Antipsychotic Therapy
This completed clinical trial update examines the effects of antipsychotic therapy on bone mineral content and bone metabolism in adolescent…
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CLINICAL_TRIALS trial_result · 2011-08-03Clinical Trial Update: Transcranial Magnetic Treatment (TMS) in Unipolar Depression [EARLY_Phase 1]
An early-phase 1 trial evaluating transcranial magnetic stimulation for major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2011-08-03Clinical Trial Update: Impact of Caregiver Depression on Asthma in the Child
This completed clinical trial from UT Southwestern Medical Center examines whether caregiver major depressive disorder affects asthma outcom…
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CLINICAL_TRIALS trial_result · 2011-08-02Clinical Trial Update: Study Evaluating the Effect of Desvenlafaxine on the Pharmacokinetics of Midazolam [Phase 4]
A Phase 4 trial evaluated whether desvenlafaxine affects the pharmacokinetics of midazolam. The study, in participants with major depressive…
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CLINICAL_TRIALS trial_result · 2011-08-02Clinical Trial Update: Internet-delivered Psychodynamic Therapy for Depression [NA]
This update reports the completion of a clinical trial evaluating internet-delivered psychodynamic therapy for depression.
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CLINICAL_TRIALS trial_result · 2011-08-01Clinical Trial Update: Exploring the Effectiveness of the 'Back of the Net' Intervention on Indices of Physical and Psychological Measures [NA]
A completed clinical trial from Dublin City University evaluating the Back of the Net intervention's effects on physical and psychological m…
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CLINICAL_TRIALS trial_result · 2011-07-28Clinical Trial Update: Identifying Very Early Response to Seroquel Extended Release (XR) Augmentation for Major Depressive Disorder [Phase 4]
Phase 4 trial evaluating very early response to quetiapine XR augmentation in adults with major depressive disorder; the study status is com…
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FDA approval · 2011-07-27FDA Approved: PAROXETINE — Supplemental Application (Zydus Lifesciences Limited)
FDA approved a supplemental application for paroxetine hydrochloride (paroxetine) from Zydus Lifesciences Limited under an ANDA.
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FDA approval · 2011-07-26FDA Approved: WELLBUTRIN XL — Supplemental Application (Bausch Health US LLC)
FDA approves a supplemental application for WELLBUTRIN XL (bupropion hydrochloride) from Bausch Health US LLC.
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FDA approval · 2011-07-26FDA Approved: APLENZIN — Supplemental Application (Bausch Health US, LLC)
FDA approved a supplemental application for APLENZIN (bupropion hydrobromide) from Bausch Health US, LLC. This action updates the product la…
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CLINICAL_TRIALS trial_result · 2011-07-21Clinical Trial Update: Repetitive Transcranial Magnetic Stimulation (rTMS) in Depression [Phase 4]
A Phase 4 trial of repetitive transcranial magnetic stimulation (rTMS) for depression has been terminated.
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CLINICAL_TRIALS withdrawal · 2011-07-20Clinical Trial Update: Enhancing the Therapeutic Efficacy of Sleep Deprivation by Modafinil [Phase 2]
A Phase 2 clinical trial investigating modafinil to enhance sleep deprivation therapy for depression has been withdrawn.
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CLINICAL_TRIALS trial_result · 2011-07-18Clinical Trial Update: Escitalopram Treatment of Major Depression in Patients With Temporal Lobe Epilepsy [Phase 4]
Phase 4 clinical trial assessing escitalopram for major depressive disorder in patients with temporal lobe epilepsy.
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CLINICAL_TRIALS other · 2011-07-15Clinical Trial Update: Bupropion SR for Major Depression and Depression NOS in Children and Adolescents With Bipolar Disorder [Phase 4]
Phase 4 trial update indicates termination of a study evaluating Bupropion SR for major depressive disorder in children and adolescents with…
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CLINICAL_TRIALS trial_result · 2011-07-14Clinical Trial Update: Exploratory Study of SPD489 in Adults With Major Depressive Disorder (MDD) as Augmentation Therapy to an Antidepressant [Phase 2]
Phase 2 exploratory study of SPD489 as augmentation to antidepressant in adults with major depressive disorder has completed with results po…
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CLINICAL_TRIALS trial_result · 2011-07-12Clinical Trial Update: N-methylglycine (Sarcosine) Treatment for Depression [Phase 2]
This clinical trial update reports the completion of a Phase 2 study evaluating sarcosine (N-methylglycine) for major depressive disorder.
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CLINICAL_TRIALS trial_result · 2011-07-11Clinical Trial Update: Effects of Fish-oil on Mood and Cognitive Functions of Healthy Individuals [NA]
ClinicalTrials.gov entry reports completion of a study evaluating the effects of fish-oil (omega-3 fatty acids) on mood and cognitive functi…
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FDA approval · 2011-07-08FDA Approved: SEROQUEL — Supplemental Application (H2-Pharma, LLC)
FDA approved a supplemental application for SEROQUEL (quetiapine) submitted by H2-Pharma, LLC.
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CLINICAL_TRIALS trial_result · 2011-07-08Clinical Trial Update: Randomized Trial of Psychotherapy for Persistently Depressed Primary Care Patients [Phase 1]
Phase 1 randomized trial evaluating psychotherapy for persistently depressed primary care patients, sponsored by Butler Hospital; the study …
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CLINICAL_TRIALS research · 2011-07-06Clinical Trial Update: A Study of Quetiapine Fumarate Sustained Release in Major Depression With Comorbid Fibromyalgia Syndrome [Phase 4]
Phase 4 trial evaluating quetiapine fumarate sustained release for major depressive disorder with comorbid fibromyalgia has completed.