Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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FDA approval · 2011-12-27FDA Approved: PAROXETINE — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA approved a supplemental application from Mylan Pharmaceuticals for paroxetine hydrochloride hemihydrate, authorizing a generic version o…
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CLINICAL_TRIALS research · 2011-12-22Clinical Trial Update: Study of Methylphenidate as Add on Therapy in Depressed Cancer Patients [Phase 3]
A Phase 3 clinical trial is evaluating methylphenidate as add-on therapy for depression in patients with cancer; the update provides no resu…
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FDA approval · 2011-12-15FDA Approved: PAROXETINE — Supplemental Application (Apotex Corp.)
FDA approved a supplemental application for Apotex Corp. to manufacture and market paroxetine hydrochloride as a generic antidepressant.
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CLINICAL_TRIALS trial_result · 2011-12-15Clinical Trial Update: Prozac Treatment of Major Depression: Discontinuation Study [Phase 4]
Completed Phase 4 discontinuation study of fluoxetine (Prozac) for adults with major depressive disorder; results from the discontinuation p…
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CLINICAL_TRIALS research · 2011-12-15Clinical Trial Update: Effect of Antidepressants on White Matter Structure [Phase 4]
An update for a Phase 4 clinical trial examining the effects of antidepressants on white matter structure in individuals with major depressi…
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CLINICAL_TRIALS research · 2011-12-15Clinical Trial Update: Psychobiological Characterization of Depression in Hepatitis C
Clinical trial investigating psychobiological characteristics of depression in patients with hepatitis C. Current status is UNKNOWN.
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CLINICAL_TRIALS research · 2011-12-08Clinical Trial Update: Aripiprazole Augmentation Versus Switching to Different Class of Antidepressants in Major Depressive Disorder [NA]
Clinical trial comparing aripiprazole augmentation to switching to a different class of antidepressants for major depressive disorder. The c…
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CLINICAL_TRIALS trial_result · 2011-12-06Clinical Trial Update: Study Comparing Adjunctive Risperidone Versus Placebo in Major Depressive Disorder That Is Not Responding to Standard Therapy [Phase 3]
A Phase 3 trial comparing adjunctive risperidone to placebo for major depressive disorder not responding to standard therapy has completed.
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CLINICAL_TRIALS trial_result · 2011-12-06Clinical Trial Update: Efficacy Study of Transcranial Direct Current Stimulation to Treat Major Depressive Disorder [Phase 2, Phase 3]
A completed Phase 2/3 trial evaluating transcranial direct current stimulation for major depressive disorder.
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CLINICAL_TRIALS trial_result · 2011-12-06Clinical Trial Update: Transcranial Direct Current Stimulation to Treat Major Depressive Disorder [Phase 2, Phase 3]
A clinical trial evaluating transcranial direct current stimulation for Major Depressive Disorder has completed Phase 2 and Phase 3 portions…
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CLINICAL_TRIALS trial_result · 2011-12-06Clinical Trial Update: Attachment Security as Mediator and Moderator of Outcome in Major Depression [NA]
This completed clinical trial evaluated whether attachment security mediates and moderates outcomes in major depression.
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CLINICAL_TRIALS research · 2011-11-30Clinical Trial Update: Electroencephalography (EEG) Signal Processing
An update on a clinical trial evaluating EEG signal processing methods in the context of Major Depressive Disorder.
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CLINICAL_TRIALS trial_result · 2011-11-23Clinical Trial Update: Interventional Study of Wellbutrin XL in Major Depressive Disorder With Atypical Features [Phase 4]
A Phase 4 interventional study evaluating Wellbutrin XL (bupropion extended-release) for major depressive disorder has been completed.
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CLINICAL_TRIALS withdrawal · 2011-11-23Clinical Trial Update: Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder [Phase 2]
A Phase 2 clinical trial investigating mitochondrial dysfunction in bipolar disorder has been withdrawn.
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FDA approval · 2011-11-22FDA Approved: FLUOXETINE — Supplemental Application (TIME CAP LABORATORIES, INC.)
FDA approved a supplemental application for fluoxetine hydrochloride from Time Cap Laboratories, Inc., enabling the generic product Fluoxeti…
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CLINICAL_TRIALS trial_result · 2011-11-22Clinical Trial Update: Cognitive Correlates of Antidepressant Treatment Response in Elders [Phase 4]
Completed Phase 4 clinical trial examining cognitive correlates of antidepressant treatment response in older adults with depression.
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CLINICAL_TRIALS trial_result · 2011-11-22Clinical Trial Update: Using a Preparation and Education Intervention to Reduce Postpartum Depression Among New Mothers (The MADE IT 2 Study) [NA]
A completed clinical trial (MADE IT 2 Study) evaluating a preparation and education intervention to reduce postpartum depression among new m…
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CLINICAL_TRIALS research · 2011-11-22Clinical Trial Update: EEG Objectification in Neuropsychiatry [NA]
This is a clinical trial update regarding EEG objectification in neuropsychiatry. It lists personality disorder and depression among the stu…
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CLINICAL_TRIALS trial_result · 2011-11-21Clinical Trial Update: Single-Dose Pharmacokinetics (PK) Study of Novel Neurogenic Compound NSI-189 [Phase 1]
A Phase 1 single-dose pharmacokinetic study of the neurogenic compound NSI-189 has been completed, supporting its development for depression…
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CLINICAL_TRIALS trial_result · 2011-11-21Clinical Trial Update: Advanced MRI in Major Depression
A completed clinical trial evaluating advanced MRI techniques in patients with major depressive disorder.
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CLINICAL_TRIALS trial_result · 2011-11-16Clinical Trial Update: Effects of Electroconvulsive Therapy (ECT) on Serotonin-1A Receptor Binding [Phase 4]
Phase 4 trial evaluating the effects of electroconvulsive therapy on serotonin-1A receptor binding in unipolar depression.
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CLINICAL_TRIALS trial_result · 2011-11-16Clinical Trial Update: Group CBT for Depression and AOD Disorders [Phase 1]
Phase 1 clinical trial update evaluating group cognitive-behavioral therapy for depression and co-occurring substance use disorders; the stu…
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CLINICAL_TRIALS trial_result · 2011-11-15Clinical Trial Update: Serotonin Transporter Genetic Variation and Amygdalar Activation Correlates of Antidepressant Response [Phase 4]
This Phase 4 clinical trial update reports that serotonin transporter genetic variation and amygdala activation correlate with antidepressan…
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FDA approval · 2011-11-10FDA Approved: BUPROPION HYDROCHLORIDE — Original Application (Upsher-Smith Laboratories, LLC)
FDA approved bupropion hydrochloride from Upsher-Smith Laboratories in an original application, authorizing its use for major depressive dis…
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CLINICAL_TRIALS trial_result · 2011-11-10Clinical Trial Update: Evaluation of Three Continuation Therapies After ECT Concerning Efficacy and Cognition in Severly Depressed Patients [Phase 1]
This Phase 1 trial evaluated three continuation therapies after electroconvulsive therapy in severely depressed patients to assess efficacy …