Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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FDA approval · 2012-07-31FDA Approved: FLUOXETINE — Supplemental Application (PAI Holdings, LLC dba PAI Pharma)
FDA approved a supplemental application for fluoxetine hydrochloride from PAI Holdings (PAI Pharma), confirming approval of a generic fluoxe…
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FDA approval · 2012-07-31FDA Approved: VENLAFAXINE — Supplemental Application (Alembic Pharmaceuticals Inc.)
FDA approved a supplemental application for venlafaxine by Alembic Pharmaceuticals Inc. to support a generic version of the antidepressant. …
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FDA approval · 2012-07-31FDA Approved: PAROXETINE — Supplemental Application (NorthStar Rx LLC)
FDA approved a supplemental application for a generic paroxetine hydrochloride product submitted by NorthStar Rx LLC.
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FDA approval · 2012-07-31FDA Approved: PAROXETINE — Supplemental Application (Zydus Lifesciences Limited)
The FDA approved a supplemental application for paroxetine hydrochloride from Zydus Lifesciences Limited, authorizing its marketing as a gen…
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Skills Based Counseling for Adherence and Depression in HIV+ Methadone Patients - 1 [NA]
Clinical trial update for a study on skills-based counseling to improve adherence and depression outcomes in HIV-positive individuals underg…
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CLINICAL_TRIALS research · 2012-07-26Clinical Trial Update: Assessment of Pituitary Adenylate Cyclase Activating Polypeptide-Brain Derived Neurotrophic Factor (PACAP-BDNF) Signaling System Involvement in Etiology and Treatment of Major Depression [NA]
This completed clinical trial evaluated the involvement of the PACAP-BDNF signaling system in the etiology and treatment of major depressive…
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CLINICAL_TRIALS trial_result · 2012-07-25Clinical Trial Update: AZD6765 Severe Major Depressive Disorder (MDD) IV [Phase 2]
A Phase 2 clinical trial update for AZD6765 in adults with Major Depressive Disorder, which has completed.
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CLINICAL_TRIALS trial_result · 2012-07-24Clinical Trial Update: Electrical Stimulation of the Internal Capsule for Intractable Depression [Phase 2]
A Phase 2 trial update reports completion of a study evaluating electrical stimulation of the internal capsule (deep brain stimulation) for …
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CLINICAL_TRIALS trial_result · 2012-07-23Clinical Trial Update: The Trauma Recovery and Empowerment Model for Treating Post-Traumatic Stress Disorder in Women [Phase 3]
Phase 3 clinical trial for the Trauma Recovery and Empowerment Model to treat Post-Traumatic Stress Disorder in women has completed.
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CLINICAL_TRIALS trial_result · 2012-07-20Clinical Trial Update: IN2SHAPE: A Study of Physical Activity and Depressive Symptoms in Adolescence [NA]
This clinical trial update reports the completed study examining the effect of physical activity on depressive symptoms in adolescence.
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CLINICAL_TRIALS trial_result · 2012-07-19Clinical Trial Update: Inflammatory Markers and Cognitive Function in Major Depression [Phase 4]
Phase 4 clinical trial update examining inflammatory markers and cognitive function in individuals with major depressive disorder; current s…
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CLINICAL_TRIALS trial_result · 2012-07-12Clinical Trial Update: Lexapro and Pramipexole and to Treat Major Depression [Phase 2]
Phase 2 trial evaluating Lexapro (escitalopram) in combination with pramipexole for major depressive disorder has completed, with results po…
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CLINICAL_TRIALS research · 2012-07-12Clinical Trial Update: Brain MRI (Magnetic Resonance Imaging) Scans of Patients With Treatment Resistant Depression (TRD) and Healthy Controls
Completed clinical trial update reporting brain MRI scans in patients with treatment-resistant depression and healthy controls, conducted by…
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CLINICAL_TRIALS trial_result · 2012-07-10Clinical Trial Update: Efficacy and Safety of Homeopathy for Moderate Depression (Acute Phase) [Phase 3]
Phase 3 trial evaluating homeopathy for moderate depressive disorder (acute phase) has been terminated.
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CLINICAL_TRIALS trial_result · 2012-07-09Clinical Trial Update: Acamprosate Added to Escitalopram and Behavioral Treatment for Comorbid Depression and Alcoholism [Phase 4]
Phase 4 trial evaluating adding acamprosate to escitalopram and behavioral therapy for comorbid major depressive disorder and alcohol use di…
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CLINICAL_TRIALS trial_result · 2012-07-09Clinical Trial Update: Duloxetine for Perimenopausal Depression [Phase 4]
A Phase 4 clinical trial evaluating duloxetine for perimenopausal depression in Major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2012-07-06Clinical Trial Update: Org 24448 to Treat Major Depression [Phase 2]
A Phase 2 trial of Org 24448 for major depressive disorder was terminated, with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-07-06Clinical Trial Update: Effectiveness of Acupuncture for Depressed Patients Taking Antidepressant Medications [NA]
A completed clinical trial evaluating the effectiveness of acupuncture for patients with depression who are taking antidepressants.
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CLINICAL_TRIALS trial_result · 2012-07-06Clinical Trial Update: Effectiveness of Acupuncture for Depressed Patients Not Taking Antidepressant Medications [NA]
A completed clinical trial evaluated the effectiveness of acupuncture for depression in patients not taking antidepressant medications.
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CLINICAL_TRIALS research · 2012-07-04Clinical Trial Update: A Prospective, Comparative Study to Explore the Efficacy and Safety of the Five Channels Multiway Deep Transcranial Magnetic Stimulation (TMS) Device in Subjects With Major Depression Disorder (MDD) [NA]
A prospective comparative trial evaluating the efficacy and safety of a five-channel deep TMS device for major depressive disorder; status d…
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CLINICAL_TRIALS trial_result · 2012-07-04Clinical Trial Update: Oral Tyramine Pressor Response Study of CX157 Tablets in Healthy Male Volunteers [Phase 1]
This clinical trial update reports the completion of a Phase 1 study evaluating the oral tyramine pressor response of CX157 tablets in healt…
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CLINICAL_TRIALS withdrawal · 2012-07-03Clinical Trial Update: Internet Intervention for the Prevention of Depression - Approaches to Improving Mood [Phase 1]
A Phase 1 trial evaluating an Internet-based intervention to prevent depression in individuals at risk has been withdrawn.
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CLINICAL_TRIALS trial_result · 2012-06-29Clinical Trial Update: The Effects of Eszopiclone and Lexapro on Prefrontal Glutamate and GABA in Depression With Anxiety and Insomnia [Phase 4]
A Phase 4 trial evaluated the effects of eszopiclone and escitalopram (Lexapro) on prefrontal glutamate and GABA in adults with depression w…
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CLINICAL_TRIALS trial_result · 2012-06-27Clinical Trial Update: Relapse Prevention Study Of Desvenlafaxine Succinate Sustained Release In Outpatients With Major Depressive Disorder [Phase 3]
Phase 3 relapse-prevention trial of desvenlafaxine sustained release in outpatients with major depressive disorder has completed with result…
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CLINICAL_TRIALS trial_result · 2012-06-27Clinical Trial Update: A Study of CX157 (TriRima) for the Treatment of Depression [Phase 2]
This Phase 2 trial of CX157 (TriRima) for Major Depressive Disorder has completed and its results have been posted.