Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-03-17Clinical Trial Update: Antidepressant Adherence Via AD_IVR [Phase 3]
Phase 3 clinical trial update on using AD_IVR to support adherence to antidepressants in Major Depressive Disorder. The document notes the s…
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CLINICAL_TRIALS research · 2015-03-17Clinical Trial Update: Oxygen Therapy in Depression [NA]
Clinical trial update examining normobaric hyperoxia (oxygen therapy) for major depressive disorder; the current status is listed as unknown…
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FDA approval · 2015-03-16FDA Approved: VIIBRYD — Supplemental Application (Allergan, Inc.)
FDA approved a supplemental application for VIIBRYD (vilazodone hydrochloride) from Allergan, Inc.
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FDA approval · 2015-03-16FDA Approved: FLUOXETINE — Original Application (Vensun Pharmaceuticals, Inc.)
The FDA approved Vensun Pharmaceuticals' original (ANDA) application for fluoxetine hydrochloride, establishing a generic fluoxetine product…
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CLINICAL_TRIALS trial_result · 2015-03-13Clinical Trial Update: Venlafaxine ER Phase 3 Study for Major Depressive Disorder (MDD) [Phase 3]
Phase 3 trial for venlafaxine extended-release in major depressive disorder completed; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Maintenance rTMS for Treatment-resistant Depression (TRD): a One-year Double Blind Controlled Study [Phase 2, Phase 3]
This clinical trial update describes a one-year, double-blind, controlled Phase 2/3 study evaluating maintenance rTMS for treatment-resistan…
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: E-Mental Health Adolescent Depression Program (LEAP) [NA]
Completed clinical trial for the LEAP e-mental health program targeting adolescent depression. Results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: Enhancing Parenting for Depressed Caregivers [NA]
This Clinical Trials update reports the completion of the study 'Enhancing Parenting for Depressed Caregivers' with results posted in 2015. …
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: Open-Label Pilot Study to Examine the Value of Substituting Quetiapine for Benzodiazepines [Phase 4]
Open-label Phase 4 pilot trial evaluating substituting quetiapine for benzodiazepines in major depressive disorder and generalized anxiety d…
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CLINICAL_TRIALS trial_result · 2015-03-05Clinical Trial Update: Paraprofessional Treatment of Depression in Vietnam [NA]
A completed clinical trial evaluating paraprofessional-delivered treatment for depressive symptoms in Vietnam. The study was sponsored by th…
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CLINICAL_TRIALS trial_result · 2015-03-04Clinical Trial Update: The Treatment of Traumatised Refugees With Sertraline Versus Venlafaxine in Combination With Psychotherapy [Phase 4]
A Phase 4 trial comparing sertraline to venlafaxine with psychotherapy in traumatized refugees has completed.
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CLINICAL_TRIALS trial_result · 2015-03-04Clinical Trial Update: Subanesthetic IV Bolus Ketamine in the Treatment of Acute Depression [Phase 1]
A Phase 1 trial evaluating subanesthetic IV ketamine for acute depression was terminated.
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CLINICAL_TRIALS trial_result · 2015-02-25Clinical Trial Update: The Effect of Traumatic Childbirth on the Incidence of PTSD and Other Major Postpartum Psychopathology
This clinical trial update investigates whether traumatic childbirth elevates the risk of post-traumatic stress disorder and other postpartu…
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CLINICAL_TRIALS trial_result · 2015-02-24Clinical Trial Update: Effect of Intranasal Insulin on Depressive Symptoms in Major Depressive Disorder [Phase 3]
A Phase 3 trial evaluating intranasal insulin for depressive symptoms in adults with major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2015-02-23Clinical Trial Update: Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia [Phase 4]
Phase 4 trial update evaluating adherence to antidepressant medication in patients with functional dyspepsia, with depression as a comorbidi…
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CLINICAL_TRIALS trial_result · 2015-02-23Clinical Trial Update: SPD489 Adult Major Depressive Disorder (MDD) Open-label Safety and Tolerability Rollover Extension Study [Phase 3]
Open-label safety and tolerability rollover extension study for SPD489 in adults with major depressive disorder; terminated, results posted …
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CLINICAL_TRIALS trial_result · 2015-02-20Clinical Trial Update: Abilify as an Adjunctive Treatment for Refractory Depression [Phase 4]
Phase 4 trial results for aripiprazole (Abilify) as an adjunctive treatment in adults with major depressive disorder have been posted; the s…
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CLINICAL_TRIALS trial_result · 2015-02-19Clinical Trial Update: SPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive Disorder [Phase 2]
Phase 2 trial update exploring SPD489 in combination with an antidepressant for adults with major depressive disorder; study completed with …
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CLINICAL_TRIALS research · 2015-02-12Clinical Trial Update: Glycemic Index/ Load and Mental Disorders
An update on a clinical trial from Isfahan University of Medical Sciences examining how dietary glycemic index and glycemic load may relate …
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CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: National Guard Outreach and Linkage to Treatment
Clinical trial evaluating outreach and linkage to treatment for veterans with PTSD and depression completed; results posted 2015-02-11.
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CLINICAL_TRIALS trial_result · 2015-02-09Clinical Trial Update: Switching From Generic Selective Serotonin Reuptake Inhibitors (SSRIs) and Selective Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) to Three Different Dose Initiation Strategies With Vilazodone [Phase 3]
Phase 3 trial evaluating three different dose initiation strategies for vilazodone after switching from generic SSRIs/SNRIs in adults with m…
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CLINICAL_TRIALS trial_result · 2015-02-09Clinical Trial Update: Treatment of Patients With Major Depressive Disorder With MK0869 (0869-060)(COMPLETED) [Phase 3]
A Phase 3 trial evaluating MK0869 for Major Depressive Disorder has completed.
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CLINICAL_TRIALS trial_result · 2015-02-09Clinical Trial Update: Vitamin D Improves Depression in Liver Patients [NA]
A completed clinical trial indicates that vitamin D3 may improve depressive symptoms in patients with chronic liver disease.
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CLINICAL_TRIALS trial_result · 2015-02-05Clinical Trial Update: Efficacy of Lu AA21004 on Cognitive Dysfunction in Major Depressive Disorder [Phase 2]
Phase 2 trial results evaluate the efficacy of Lu AA21004 (vortioxetine) on cognitive dysfunction in patients with major depressive disorder…
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CLINICAL_TRIALS trial_result · 2015-02-04Clinical Trial Update: Efficacy Study of CLR3001 in Depression
An efficacy study of CLR3001 in depression has completed (NCT01158547), sponsored by Clera Inc.