Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-12-16Clinical Trial Update: Does Sleep Quality Change After Switch From Wellbutrin SR to Wellbutrin XL in Patients With Major Depressive Disorder? [Phase 1]
A Phase 1 trial examined whether switching from Wellbutrin SR to Wellbutrin XL affects sleep quality in adults with major depressive disorde…
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CLINICAL_TRIALS trial_result · 2015-12-16Clinical Trial Update: Pharmacokinetics - Pharmacodynamic Study of HT-2157 in Healthy Subjects and in Patients With Major Depressive Disorder [Phase 1, Phase 2]
The study assessed the pharmacokinetics and pharmacodynamics of HT-2157 in healthy volunteers (Phase 1) and in patients with major depressiv…
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CLINICAL_TRIALS trial_result · 2015-12-16Clinical Trial Update: Effect of Quetiapine on Sleep Architecture in Bipolar Depression and Major Depressive Disorder
Clinical trial update examining the effect of quetiapine on sleep architecture in bipolar depression and major depressive disorder. The stud…
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CLINICAL_TRIALS trial_result · 2015-12-16Clinical Trial Update: Effect of Electroconvulsive Therapy (ECT) and Transcranial Magnetic Stimulation(TMS) on Brain Derived Neurotrophic Factor (BDNF) in Depressed Patients.
This document reports the completion of a clinical trial evaluating how electroconvulsive therapy and transcranial magnetic stimulation affe…
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CLINICAL_TRIALS trial_result · 2015-12-15Clinical Trial Update: Mindfulness-Based Yoga Intervention for Women With Depression [NA]
This trial entry indicates that a Mindfulness-Based Yoga Intervention trial for women with Depression has completed.
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CLINICAL_TRIALS withdrawal · 2015-12-15Clinical Trial Update: Mobile Apps for the Treatment of Depression [NA]
The clinical trial evaluating mobile apps for treating major depressive disorder has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-12-15Clinical Trial Update: Motivational Interviewing and Cognitive Behavioral Therapy-based Intervention for Cardiovascular Disease Prevention Amongst American Indians With Diabetic and Depressive Symptoms [NA]
The study NCT01892124 completed, evaluating a motivational interviewing and cognitive-behavioral therapy–based intervention for cardiovascul…
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FDA approval · 2015-12-15FDA Approved: CITALOPRAM HYDROBROMIDE — Original Application (Camber Pharmaceuticals, Inc.)
FDA approved Camber Pharmaceuticals' generic citalopram hydrobromide tablets under an Original Application (ANDA) for major depressive disor…
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CLINICAL_TRIALS research · 2015-12-11Clinical Trial Update: Creatine for Depressed Male and Female Methamphetamine Users [Phase 3]
Phase 3 clinical trial is evaluating creatine for depression and methamphetamine use disorder, with recruitment ongoing.
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CLINICAL_TRIALS research · 2015-12-11Clinical Trial Update: Integral Assessment in Unipolar Depression [Phase 4]
Phase 4 clinical trial update on integral assessment in Major Depressive Disorder sponsored by the University of Sao Paulo.
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CLINICAL_TRIALS trial_result · 2015-12-10Clinical Trial Update: Comprehensive Program for Youth Mental Health [NA]
A completed clinical trial update from the University of Alberta describing a comprehensive youth mental health program for depression and a…
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CLINICAL_TRIALS trial_result · 2015-12-10Clinical Trial Update: Regulation of Arginine-vasopressin (AVP) [NA]
Completed Yale-sponsored clinical trial studying the regulation of arginine-vasopressin (AVP) in schizophrenia and depression.
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CLINICAL_TRIALS trial_result · 2015-12-09Clinical Trial Update: Randomized Control Trial of an Animal-Assisted Intervention With Adjudicated Youth [Phase 3]
Phase 3 randomized controlled trial evaluating an animal-assisted intervention for adjudicated youth, addressing conduct disorder, depressio…
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CLINICAL_TRIALS research · 2015-12-09Clinical Trial Update: Trial of the Clinical and Cost Effectiveness of a Specialist Expert Mood Disorder Team for Refractory Unipolar Depressive Disorder [NA]
This document is a clinical trial update on evaluating the clinical and cost effectiveness of a Specialist Expert Mood Disorder Team for ref…
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CLINICAL_TRIALS trial_result · 2015-12-08Clinical Trial Update: Multicomponent Yoga Intervention for Major Depressive Disorder [Phase 2]
Phase 2 clinical trial evaluating a multicomponent yoga intervention for Major Depressive Disorder has completed.
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CLINICAL_TRIALS trial_result · 2015-12-07Clinical Trial Update: A Positron Emission Topographic (PET) Study on Depression Patient With Electroacupuncture [NA]
This entry reports the completion of a PET imaging study evaluating electroacupuncture for depression in patients with major depressive diso…
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CLINICAL_TRIALS trial_result · 2015-12-07Clinical Trial Update: Study of Depression-Ketamine-Brain Function [Phase 2]
A Phase 2 study evaluating ketamine's effects on brain function in major depressive disorder was terminated.
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CLINICAL_TRIALS trial_result · 2015-12-07Clinical Trial Update: Cortisol Evaluation in Abuse Survivors
A University of Bristol trial evaluating cortisol levels in survivors of abuse with depression and related anxiety disorders has completed.
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CLINICAL_TRIALS research · 2015-12-07Clinical Trial Update: The Effect of Escitalopram on Mood, Quality of Life and Cognitive Functioning in Glioblastoma Patients [Phase 2, Phase 3]
This document discusses a clinical trial evaluating escitalopram for mood, quality of life, and cognitive function in glioblastoma patients.…
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CLINICAL_TRIALS trial_result · 2015-12-04Clinical Trial Update: A Paroxetine- and Placebo-Controlled Study of 50 mg/Day and 100 mg/Day of EB-1010 Among Outpatients With Major Depressive Disorder Who Have Responded Inadequately to Prior Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin Norepinephrine Reuptake Inhibitors (SNRIs) [Phase 2, Phase 3]
A completed Phase 2/3 trial evaluated EB-1010 at 50 mg/day and 100 mg/day against paroxetine and placebo in outpatients with major depressiv…
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CLINICAL_TRIALS trial_result · 2015-12-04Clinical Trial Update: Mindfulness-Based Cognitive Therapy + Safety Planning For Suicidal Behavior [Phase 1]
Phase 1 clinical trial of Mindfulness-Based Cognitive Therapy plus Safety Planning for suicidal behavior has completed. It targeted individu…
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FDA approval · 2015-12-03FDA Approved: MIRTAZAPINE — Supplemental Application (Apotex Corp.)
The FDA approved a supplemental application for Apotex Corp. to market a generic formulation of mirtazapine.
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Study of the Safety and Efficacy of OPC-34712 as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder [Phase 2]
Phase 2 study evaluating the safety and efficacy of OPC-34712 as adjunctive therapy for adults with Major depressive disorder; results have …
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Anti-INFLammatory to Address Mood and Endothelial Dysfunction (INFLAMED) [Phase 2]
Phase 2 trial update of an anti-inflammatory therapy (INFLAMED) for mood symptoms in major depressive disorder; results were posted after co…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Pharmacogenetic-Directed Treatment for Major Depression [NA]
A completed clinical trial from Assurex Health evaluates pharmacogenetic-directed treatment for major depression, exploring whether tailorin…