Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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FDA approval · 2016-02-09FDA Approved: BUPROPION HYDROCHLORIDE (SR) — Original Application (Cipla USA Inc.,)
The FDA approves Cipla USA Inc.'s original application for a generic sustained-release formulation of bupropion hydrochloride (SR).
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CLINICAL_TRIALS trial_result · 2016-02-05Clinical Trial Update: Naltrexone & SSRI in Alcoholics With Depression/PTSD [Phase 3]
Phase 3 trial evaluating the combination of naltrexone and an SSRI in individuals with alcohol use disorder and comorbid depression and PTSD…
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CLINICAL_TRIALS trial_result · 2016-02-05Clinical Trial Update: Coronary Heart Disease Incidence: Depression & Inflammation Risk
A completed clinical trial update assessing whether depression and inflammation influence the incidence of coronary heart disease.
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CLINICAL_TRIALS trial_result · 2016-02-05Clinical Trial Update: Effect of African Drumming in Mood Disorders
This clinical trial update reports that a study evaluating African drumming as an intervention for mood disorders has completed. The sponsor…
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CLINICAL_TRIALS trial_result · 2016-02-05Clinical Trial Update: Physician Led Counseling in Management of Depression in Type 2 Diabetes Mellitus [NA]
A completed clinical trial assessing physician-led counseling for depression management in individuals with type 2 diabetes mellitus.
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CLINICAL_TRIALS trial_result · 2016-02-04Clinical Trial Update: Progressive Muscle Relaxation Effect on Sleep Quality, Depression and Stress in People With Multiple Sclerosis [Phase 2]
A Phase 2 clinical trial assessing whether progressive muscle relaxation improves sleep quality, depression, and stress in people with Multi…
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CLINICAL_TRIALS trial_result · 2016-02-04Clinical Trial Update: Phase 1 Study to Assess the Safety/Tolerability of Brexpiprazole as Adjunctive Therapy in Elderly Subjects With Major Depressive Disorder [Phase 1]
Phase 1 study evaluating the safety and tolerability of brexpiprazole as adjunctive therapy in elderly patients with major depressive disord…
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CLINICAL_TRIALS trial_result · 2016-02-04Clinical Trial Update: A Study to Investigate the Effect of JNJ-42847922 on Polysomnography Measures in Patients With Major Depressive Disorder With Insomnia Who Are Stably Treated With Antidepressants [Phase 1]
A Phase 1 clinical trial update evaluating how JNJ-42847922 affects polysomnography measures in adults with major depressive disorder and in…
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CLINICAL_TRIALS trial_result · 2016-02-03Clinical Trial Update: MR Imaging Biomarkers of Disease Response to ECT (Electroconvulsive Therapy) in Depression
This completed trial report discusses magnetic resonance imaging biomarkers that track or predict response to electroconvulsive therapy in p…
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CLINICAL_TRIALS trial_result · 2016-02-03Clinical Trial Update: New Technologies for Cognitive Behavior Therapy (CBT) Treatment of Adolescent Depression [NA]
A clinical trial update noting the completion of a study evaluating new technologies to deliver cognitive behavioral therapy for adolescent …
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FDA approval · 2016-02-02FDA Approved: IMIPRAMINE HYDROCHLORIDE — Supplemental Application (Lupin Pharmaceuticals, Inc.)
FDA approved Lupin Pharmaceuticals' supplemental application for imipramine hydrochloride (ANDA 090441), a generic antidepressant.
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FDA approval · 2016-02-02FDA Approved: IMIPRAMINE PAMOATE — Supplemental Application (Hikma Pharmaceuticals USA Inc)
The FDA approved a supplemental application for Imipramine Pamoate by Hikma Pharmaceuticals USA Inc, indicating an approved change to an exi…
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FDA approval · 2016-02-02FDA Approved: ESCITALOPRAM OXALATE — Supplemental Application (Camber Pharmaceuticals, Inc.)
The FDA approved a supplemental application for Camber Pharmaceuticals to offer escitalopram oxalate as a generic antidepressant, expanding …
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CLINICAL_TRIALS trial_result · 2016-01-29Clinical Trial Update: Paliperidone and Lithium in the Treatment of Suicidality - Treatment Indication and Epigenetic Regulation [Phase 4]
Phase 4 clinical trial evaluating the combination of paliperidone and lithium for suicidality in adults with major depressive disorder. The …
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CLINICAL_TRIALS trial_result · 2016-01-29Clinical Trial Update: Development of an Insomnia Treatment for Depressed Adolescents [NA]
A clinical trial conducted by the University of Michigan to develop an insomnia treatment for adolescents with depression has completed.
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FDA approval · 2016-01-28FDA Approved: LEXAPRO — Supplemental Application (Allergan, Inc.)
FDA approved a supplemental application for Lexapro (escitalopram) by Allergan, Inc. The action updates the product labeling per the approve…
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Serotonin Transporter Density in Late-life Depression With and Without Dementia [Phase 2]
This Phase 2 clinical trial update examines serotonin transporter density in older adults with depression, comparing those with and without …
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Neurorestorative Effects of Electroconvulsive Therapy (ECT) in Patients With Severe Late Life Depression [NA]
This completed clinical trial from KU Leuven evaluated the neurorestorative effects of electroconvulsive therapy in patients with severe lat…
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Antidepressants to Promote Recovery of Cardiac Patients Suffering From Depression [Phase 4]
Phase 4 trial evaluating antidepressants to promote recovery in patients with acute coronary syndrome and depression has been terminated.
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CLINICAL_TRIALS research · 2016-01-28Clinical Trial Update: Open-Label Placebo for the Treatment of Depression [NA]
An open-label placebo trial for Major Depressive Disorder is being conducted by Shalvata Mental Health Center. The current status is listed …
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CLINICAL_TRIALS research · 2016-01-27Clinical Trial Update: Behavioral Therapy Development for Methamphetamine Abuse [Phase 1]
A Phase 1 clinical trial update for a behavioral therapy targeting methamphetamine use disorder, which has been terminated; the trial lists …
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FDA approval · 2016-01-26FDA Approved: VENLAFAXINE HYDROCHLORIDE — Supplemental Application (Aurobindo Pharma Limited)
FDA approves a supplemental application for venlafaxine hydrochloride from Aurobindo Pharma Limited.
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FDA approval · 2016-01-22FDA Approved: ESCITALOPRAM — Supplemental Application (Rising Pharma Holdings, Inc.)
FDA approved a supplemental application for escitalopram from Rising Pharma Holdings, Inc.
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CLINICAL_TRIALS trial_result · 2016-01-22Clinical Trial Update: Life Goals Collaborative Care to Improve Health Outcomes in Mental Disorders [NA]
The Life Goals Collaborative Care trial evaluating health outcomes in mental disorders has completed, with results posted on Jan 22, 2016.
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CLINICAL_TRIALS trial_result · 2016-01-22Clinical Trial Update: Neuropsychobiological Correlates of Sex-steroid Hormone Manipulation in Healthy Women: a Risk Model for Depression [NA]
This entry notes the completion of a clinical trial investigating the neuropsychobiological correlates of sex-steroid hormone manipulation i…